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                                   Heat Shock Protein 20 (HSP20) MoAb--200ug
                                                 G-HSP20-200n


   Description: The HSP20-11 monoclonal antibody to human HSP20 is produced by hybridoma cell line, generated
    after hybridization of Sp 2/0 myeloma cells with spleen cells of Balb/c mice, immunized with recombinant
                                                  human HSP20.
    The HSP20 was demonstrated to constitute up to 1.3% of the total cellular protein in vertebrate tissues,
   especially in muscle and its expression is related to the muscle contraction, specifically in slow-twitch
     muscle. HSP20 may form different hetercomplexes with other HSP's, such as alpha-crystalline and HSP25.
    Phosphorylated form of HSP20 is proposed to interact with monomeric actin whereas dephosphorylated form
    binds polymeric actin filaments. In normal conditions HSP20 is diffusely disturbed in cytosol, but under
                        the heat stress it undergoes translocation to membrane fraction.
    Applications: MoAb HSP-11 can be used for HSP20 detection in ELISA, Western blotting, immunofluorescent
                                             cell culture staining.
                                              Host Species: Mouse
                                           Antigen: Recombinant HSP20
                                                Clones: HSP20-11
                                            Mouse Isotype-Clone IgG
           Form: Purified by protein-A affinity chromatography. Purity is tested by electrophoresis.
                                   Related Disciplines: Serum Protein Reagent
                                  Concentration: in PBS, pH7.4 with 0.1% NaN3.
   Specificity: MoAb HSP20-11 recognizes human recombinant HSP20 protein and HSP20 from human and rat cardiac
                   tissue extracts. For additional information, please see graphs and photos.
                                         Shipping Conditions: Blue Ice
                                            Storage Conditions: +4C
     Material Safety: All products are for research or manufacturing purposes only, and are not for use in
             human therapeutic procedures. Proper laboratory procedures should be used in handling.
                                                  Units: 200ug
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                                          Advanced ImmunoChemical Inc
                                         customerservice@advimmuno.com
                                       Phone: 800.788.0034 / 562.434.4676
                                               Fax: 562.494.3776
                                              105 Claremont Avenue
                                          Long Beach, California 90803

                           Please note: all prices subject to change without notice.
