BLASTP 2.9.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro
A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and
David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new
generation of protein database search programs", Nucleic
Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Stephen
F. Altschul, John C. Wootton, E. Michael Gertz, Richa
Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and
Yi-Kuo Yu (2005) "Protein database searches using
compositionally adjusted substitution matrices", FEBS J.
272:5101-5109.


RID: BEHT7T1Y014


Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
           198,058,131 sequences; 72,054,367,693 total letters
Query= P43423.1 RecName: Full=Modification methylase BseCI; Short=M.BseCI;
AltName: Full=Adenine-specific methyltransferase BseCI

Length=579


                                                                   Score        E      Max
Sequences producing significant alignments:                       (Bits)     Value   ident

P43423.1 RecName: Full=Modification methylase BseCI; Short=M.B...  1182       0.0     100%        
AAF04626.1 DNA methyltransferase [Geobacillus stearothermophilus]  1165       0.0     99%         
TCL51087.1 TaqI restriction endonuclease [Thermolongibacillus ...  1102       0.0     93%         
WP_132947968.1 methyltransferase domain-containing protein [Th...  1099       0.0     93%         
ACJ34595.1 Adenine-specific DNA methyltransferase BseCI [Anoxy...  1097       0.0     93%         
WP_041639364.1 methyltransferase domain-containing protein [An...  1095       0.0     93%         
WP_003331201.1 methyltransferase domain-containing protein [Ba...  668        0.0     58%         
WP_021624002.1 methyltransferase domain-containing protein [An...  657        0.0     56%         
WP_005831616.1 MULTISPECIES: methyltransferase domain-containi...  657        0.0     57%         
WP_111948994.1 methyltransferase domain-containing protein [Do...  651        0.0     55%         
P22772.1 RecName: Full=Modification methylase BanIII; Short=M....  648        0.0     56%         
WP_110899598.1 methyltransferase domain-containing protein [Pa...  622        0.0     54%         
WP_017474986.1 MULTISPECIES: methyltransferase [Bacteria]          567        0.0     51%         
CAA58443.1 methyltransferase [Aneurinibacillus aneurinilyticus]    549        0.0     54%         
WP_134157076.1 methyltransferase domain-containing protein [Ba...  546        0.0     50%         
TDY53733.1 TaqI restriction endonuclease [Bacillus subtilis]       545        0.0     50%         
PYV21223.1 modification methylase [Acidobacteria bacterium]        544        0.0     46%         
PSQ89734.1 modification methylase [Bacteroidetes bacterium QS_...  536        0.0     46%         
WP_098331187.1 methyltransferase domain-containing protein [Ba...  525        4e-178  48%         
WP_133391247.1 modification methylase [Algoriphagus sp. F21]       515        2e-174  46%         
WP_130059682.1 methyltransferase domain-containing protein [Ba...  509        6e-172  47%         
RIK81909.1 modification methylase [Planctomycetes bacterium]       504        6e-170  45%         
ADX97298.1 M.ClaI [Caryophanon latum]                              504        8e-170  46%         
WP_026473107.1 hypothetical protein [Alkaliflexus imshenetskii]    501        7e-169  46%         
WP_091102821.1 hypothetical protein [Flavobacterium marinum]       492        4e-165  47%         
WP_069512061.1 modification methylase [Lysinibacillus sphaericus]  488        1e-163  45%         
WP_093363758.1 hypothetical protein [Sphingobacterium wenxiniae]   488        2e-163  47%         
WP_094415660.1 methyltransferase domain-containing protein [Fl...  482        1e-161  45%         
WP_034298709.1 methyltransferase domain-containing protein [Al...  479        2e-160  46%         
WP_103913699.1 methyltransferase domain-containing protein [Ch...  478        5e-160  45%         
WP_127822314.1 methyltransferase domain-containing protein [Fl...  478        8e-160  45%         
WP_108778098.1 methyltransferase domain-containing protein [Fl...  477        2e-159  45%         
OXA83254.1 hypothetical protein B0A56_02000 [Flavobacterium co...  475        1e-158  45%         
WP_123910345.1 methyltransferase domain-containing protein [Fl...  474        2e-158  45%         
OWP85851.1 hypothetical protein BWK60_11905 [Flavobacterium co...  473        4e-158  45%         
WP_114900907.1 modification methylase [Kordia sp. SMS9]            465        6e-155  44%         
WP_035188037.1 methyltransferase domain-containing protein [La...  464        2e-154  43%         
CDD19860.1 dNA methyltransferase [Prevotella sp. CAG:732]          463        2e-154  45%         
WP_025017878.1 hypothetical protein [Bacteroides sartorii]         451        3e-149  42%         
WP_121123835.1 modification methylase [Sphingobacterium sp. M0...  451        9e-149  43%         
WP_036861574.1 hypothetical protein [Prevotella melaninogenica]    449        2e-148  42%         
WP_108633097.1 modification methylase [Sphingobacterium sp. M46]   448        4e-148  43%         
RYD86055.1 type II restriction endonuclease subunit M [Verruco...  448        6e-148  41%         
RAS63630.1 TaqI restriction endonuclease [Lechevalieria atacam...  447        7e-148  40%         
WP_112228736.1 methyltransferase domain-containing protein [Le...  447        9e-148  40%         
WP_104380928.1 modification methylase [Sphingobacterium sp. HM...  445        6e-147  43%         
PWK91816.1 TaqI restriction endonuclease [Lechevalieria deserti]   445        6e-147  40%         
CDA48400.1 type I restriction-modification system methyltransf...  444        7e-147  41%         
WP_109632688.1 methyltransferase domain-containing protein [Le...  445        7e-147  40%         
WP_006347600.1 DNA methyltransferase [Streptomyces tsukubensis]    442        6e-146  40%         
WP_050696484.1 hypothetical protein [Prevotella fusca]             441        1e-145  41%         
RJX29416.1 methyltransferase domain-containing protein [Desulf...  431        3e-141  41%         
OIO98490.1 type II restriction endonuclease subunit M [Anaerol...  430        6e-141  37%         
WP_099443011.1 methyltransferase domain-containing protein [Ca...  429        1e-140  37%         
RME48647.1 type II restriction endonuclease subunit M [Deltapr...  429        2e-140  39%         
RCK79459.1 type II DNA modification methyltransferase [Candida...  428        3e-140  39%         
WP_086867621.1 hypothetical protein [Streptomyces viridochromo...  427        4e-140  41%         
SBT08119.1 Type II DNA modification methyltransferase [Candida...  426        2e-139  38%         
OGI46383.1 type II restriction endonuclease subunit M [Candida...  426        3e-139  39%         
WP_064017490.1 methyltransferase domain-containing protein [Br...  425        5e-139  39%         
WP_025078928.1 hypothetical protein [Prevotella fusca]             423        6e-139  42%         
WP_124330052.1 type II restriction endonuclease subunit M [Des...  424        9e-139  38%         
WP_051340091.1 hypothetical protein [Planktothrix agardhii]        421        2e-137  40%         
RMG80293.1 type II restriction endonuclease subunit M [Chlorof...  418        2e-136  39%         
RJP32541.1 type II restriction endonuclease subunit M [Phycisp...  418        3e-136  41%         
TAM48199.1 type II restriction endonuclease subunit M [Gammapr...  417        4e-136  39%         
WP_081054411.1 type II restriction endonuclease subunit M [Bur...  417        1e-135  38%         
WP_128588433.1 type II restriction endonuclease subunit M [Pse...  416        2e-135  38%         
PZR07375.1 type II restriction endonuclease subunit M [Azospir...  414        6e-135  37%         
OQX00972.1 type II restriction endonuclease subunit M [Thiothr...  414        7e-135  39%         
WP_085378765.1 hypothetical protein [Paracoccus contaminans]       413        1e-134  39%         
WP_118089112.1 type II restriction endonuclease subunit M [Vib...  411        5e-134  40%         
OJW39010.1 type II restriction endonuclease subunit M [Rhodano...  412        6e-134  37%         
WP_029151739.1 type II restriction endonuclease subunit M [Met...  412        7e-134  40%         
RGP84823.1 type II restriction endonuclease subunit M [Vibrio ...  411        7e-134  40%         
OYU47886.1 type II restriction endonuclease subunit M [Rhizobi...  410        3e-133  38%         
WP_104318211.1 methyltransferase domain-containing protein [Ra...  409        5e-133  37%         
OUL86845.1 type II restriction endonuclease subunit M [Parabur...  409        7e-133  38%         
WP_122720126.1 type II restriction endonuclease subunit M [Pse...  409        8e-133  38%         
WP_086909745.1 type II restriction endonuclease subunit M [Par...  409        1e-132  38%         
ANO50441.1 hypothetical protein BA177_03760 [Woeseia oceani]       408        1e-132  39%         
WP_082990274.1 hypothetical protein [Woeseia oceani]               407        2e-132  39%         
WP_104316347.1 methyltransferase domain-containing protein [Ra...  407        2e-132  37%         
WP_093068541.1 type II restriction endonuclease subunit M [Thi...  405        2e-131  39%         
WP_100876757.1 methyltransferase domain-containing protein [Ja...  405        3e-131  38%         
PKB22639.1 TaqI restriction endonuclease [Janthinobacterium sp...  405        1e-130  38%         
WP_107673145.1 type II restriction endonuclease subunit M [Rho...  405        2e-130  38%         
OAE13151.1 type II restriction endonuclease subunit M [Pseudom...  401        3e-130  40%         
KVF76647.1 type II restriction endonuclease subunit M [Burkhol...  401        3e-130  39%         
WP_082428003.1 type II restriction endonuclease subunit M [Pse...  402        9e-130  39%         
WP_084055495.1 type II restriction endonuclease subunit M [Car...  401        2e-129  40%         
WP_107722796.1 type II restriction endonuclease subunit M [Cel...  398        3e-129  40%         
WP_133366234.1 type II restriction endonuclease subunit M [Qip...  400        3e-129  37%         
WP_023173732.1 N5-glutamine S-adenosyl-L-methionine-dependent ...  399        3e-129  35%         
WP_126298546.1 methyltransferase domain-containing protein [Co...  399        5e-129  37%         
WP_034672720.1 hypothetical protein [Acinetobacter sp. 272263]     398        9e-129  35%         
WP_128614130.1 type II restriction endonuclease subunit M [Pse...  399        1e-128  37%         
WP_005523499.1 methyltransferase domain-containing protein [Co...  398        1e-128  38%         
WP_077555043.1 type II restriction endonuclease subunit M [Rho...  398        2e-128  35%         
WP_125825032.1 type II restriction endonuclease subunit M [Aci...  398        2e-128  35%         

ALIGNMENTS
>P43423.1 RecName: Full=Modification methylase BseCI; Short=M.BseCI; AltName: 
Full=Adenine-specific methyltransferase BseCI
 CAA56041.1 methyltransferase, partial [Geobacillus stearothermophilus]
Length=579

 Score = 1182 bits (3058),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 579/579 (100%), Positives = 579/579 (100%), Gaps = 0/579 (0%)

Query  1    MMSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA  60
            MMSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA
Sbjct  1    MMSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA  60

Query  61   INKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN  120
            INKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN
Sbjct  61   INKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN  120

Query  121  IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGII  180
            IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGII
Sbjct  121  IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGII  180

Query  181  GVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKE  240
            GVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKE
Sbjct  181  GVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKE  240

Query  241  NSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPEN  300
            NSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPEN
Sbjct  241  NSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPEN  300

Query  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360
            YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE
Sbjct  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360

Query  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420
            DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL
Sbjct  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420

Query  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480
            ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK
Sbjct  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480

Query  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540
            KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI
Sbjct  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540

Query  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESLKY  579
            ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESLKY
Sbjct  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESLKY  579


>AAF04626.1 DNA methyltransferase [Geobacillus stearothermophilus]
Length=579

 Score = 1165 bits (3013),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 571/579 (99%), Positives = 573/579 (99%), Gaps = 0/579 (0%)

Query  1    MMSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA  60
            MMSVQKA  VSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA
Sbjct  1    MMSVQKAKHVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA  60

Query  61   INKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN  120
            INKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN
Sbjct  61   INKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN  120

Query  121  IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGII  180
            IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGII
Sbjct  121  IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGII  180

Query  181  GVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKE  240
            GVITSNRYLTTKGG STRKFLVSNFNILEIMDLGD+KFFEAAVLPAIFFGEKKNKEYQKE
Sbjct  181  GVITSNRYLTTKGGESTRKFLVSNFNILEIMDLGDTKFFEAAVLPAIFFGEKKNKEYQKE  240

Query  241  NSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPEN  300
            NSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSV DKTYSISLGK+ISPEN
Sbjct  241  NSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVGDKTYSISLGKLISPEN  300

Query  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360
            YKEPWILATEDEYEWF KVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE
Sbjct  301  YKEPWILATEDEYEWFTKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360

Query  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420
            DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL
Sbjct  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420

Query  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480
            ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPD SPEPKFFYEDKGSVVDGNCYWIIPK
Sbjct  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDISPEPKFFYEDKGSVVDGNCYWIIPK  480

Query  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540
            KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI
Sbjct  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540

Query  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESLKY  579
            ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESLKY
Sbjct  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESLKY  579


>TCL51087.1 TaqI restriction endonuclease [Thermolongibacillus altinsuensis]
Length=577

 Score = 1102 bits (2849),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 536/577 (93%), Positives = 557/577 (97%), Gaps = 0/577 (0%)

Query  1    MMSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA  60
            MMSVQK   VS+QKATGAHFTPDKLAEVIAKRIL+YFKGE+ RVIRVLDPACGDGELLLA
Sbjct  1    MMSVQKVKQVSKQKATGAHFTPDKLAEVIAKRILNYFKGEEKRVIRVLDPACGDGELLLA  60

Query  61   INKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN  120
            INKVAQSMNIQLELIGVD DIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN
Sbjct  61   INKVAQSMNIQLELIGVDSDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN  120

Query  121  IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGII  180
             EELEP DIIIANPPYVRTQILGAEKAQ+LR+KFNLKGRVDLYQAFLVAMTQQLKSNGI+
Sbjct  121  TEELEPADIIIANPPYVRTQILGAEKAQQLRKKFNLKGRVDLYQAFLVAMTQQLKSNGIM  180

Query  181  GVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKE  240
            GVITSNRYLTTKGG S RKFLV NFNILEIMDLGD+KFF+AAVLPAIFFGEKK+KE QKE
Sbjct  181  GVITSNRYLTTKGGESIRKFLVLNFNILEIMDLGDTKFFDAAVLPAIFFGEKKSKENQKE  240

Query  241  NSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPEN  300
            NSNVPKFFKIYEQ+DIEAS++VNSEFNSLIELLEVNKSGLYSV DKTYSISLGK+ISPEN
Sbjct  241  NSNVPKFFKIYEQNDIEASTNVNSEFNSLIELLEVNKSGLYSVRDKTYSISLGKLISPEN  300

Query  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360
            YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDW ELPE+QIPE
Sbjct  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWEELPEQQIPE  360

Query  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420
            DKLLRPIISADQANKWSVSL+ +NKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL
Sbjct  361  DKLLRPIISADQANKWSVSLIESNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420

Query  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480
            A R YVLKANRNWYEIWVPHDPSLWDKPKIIFPD S EPKFFYEDKGS+VDGNCYWIIPK
Sbjct  421  AGRTYVLKANRNWYEIWVPHDPSLWDKPKIIFPDISSEPKFFYEDKGSIVDGNCYWIIPK  480

Query  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540
            KEN NDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIP+PESIYSKEI
Sbjct  481  KENDNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPNPESIYSKEI  540

Query  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            ISLV+ELVNNKKE Q+INEIENRIE+LILRAFDIESL
Sbjct  541  ISLVKELVNNKKEAQEINEIENRIEELILRAFDIESL  577


>WP_132947968.1 methyltransferase domain-containing protein [Thermolongibacillus 
altinsuensis]
Length=576

 Score = 1099 bits (2843),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 535/576 (93%), Positives = 556/576 (97%), Gaps = 0/576 (0%)

Query  2    MSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAI  61
            MSVQK   VS+QKATGAHFTPDKLAEVIAKRIL+YFKGE+ RVIRVLDPACGDGELLLAI
Sbjct  1    MSVQKVKQVSKQKATGAHFTPDKLAEVIAKRILNYFKGEEKRVIRVLDPACGDGELLLAI  60

Query  62   NKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNI  121
            NKVAQSMNIQLELIGVD DIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN 
Sbjct  61   NKVAQSMNIQLELIGVDSDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNT  120

Query  122  EELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIG  181
            EELEP DIIIANPPYVRTQILGAEKAQ+LR+KFNLKGRVDLYQAFLVAMTQQLKSNGI+G
Sbjct  121  EELEPADIIIANPPYVRTQILGAEKAQQLRKKFNLKGRVDLYQAFLVAMTQQLKSNGIMG  180

Query  182  VITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKEN  241
            VITSNRYLTTKGG S RKFLV NFNILEIMDLGD+KFF+AAVLPAIFFGEKK+KE QKEN
Sbjct  181  VITSNRYLTTKGGESIRKFLVLNFNILEIMDLGDTKFFDAAVLPAIFFGEKKSKENQKEN  240

Query  242  SNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENY  301
            SNVPKFFKIYEQ+DIEAS++VNSEFNSLIELLEVNKSGLYSV DKTYSISLGK+ISPENY
Sbjct  241  SNVPKFFKIYEQNDIEASTNVNSEFNSLIELLEVNKSGLYSVRDKTYSISLGKLISPENY  300

Query  302  KEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPED  361
            KEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDW ELPE+QIPED
Sbjct  301  KEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWEELPEQQIPED  360

Query  362  KLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLA  421
            KLLRPIISADQANKWSVSL+ +NKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLA
Sbjct  361  KLLRPIISADQANKWSVSLIESNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLA  420

Query  422  SRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKK  481
             R YVLKANRNWYEIWVPHDPSLWDKPKIIFPD S EPKFFYEDKGS+VDGNCYWIIPKK
Sbjct  421  GRTYVLKANRNWYEIWVPHDPSLWDKPKIIFPDISSEPKFFYEDKGSIVDGNCYWIIPKK  480

Query  482  ENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEII  541
            EN NDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIP+PESIYSKEII
Sbjct  481  ENDNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPNPESIYSKEII  540

Query  542  SLVRELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            SLV+ELVNNKKE Q+INEIENRIE+LILRAFDIESL
Sbjct  541  SLVKELVNNKKEAQEINEIENRIEELILRAFDIESL  576


>ACJ34595.1 Adenine-specific DNA methyltransferase BseCI [Anoxybacillus flavithermus 
WK1]
Length=577

 Score = 1097 bits (2837),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 534/577 (93%), Positives = 556/577 (96%), Gaps = 0/577 (0%)

Query  1    MMSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA  60
            MMSVQK   VS+QKATGAHFTPDKLAEVIAKRIL+YFKGE+ RVIRVLDPACGDGELLLA
Sbjct  1    MMSVQKVKQVSKQKATGAHFTPDKLAEVIAKRILNYFKGEEKRVIRVLDPACGDGELLLA  60

Query  61   INKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN  120
            INKVAQSMNIQLELIGVD DIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN
Sbjct  61   INKVAQSMNIQLELIGVDSDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN  120

Query  121  IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGII  180
             EELEP DIIIANPPYVRTQILGAEKAQ+LR+KFNLKGRVDLYQAFLVAMTQQLKSNGI+
Sbjct  121  TEELEPADIIIANPPYVRTQILGAEKAQQLRKKFNLKGRVDLYQAFLVAMTQQLKSNGIM  180

Query  181  GVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKE  240
            GVITSNRYLTTKGG S RKFLV NFNILEIMDLGD+KFF+AAVLPAIFFGEKK+KE QKE
Sbjct  181  GVITSNRYLTTKGGESIRKFLVLNFNILEIMDLGDTKFFDAAVLPAIFFGEKKSKENQKE  240

Query  241  NSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPEN  300
            NSNVPKFFKIYEQ+DIEAS++VNSEFNSLIELLEVNKSGLYSV DKTYSISLGK+ISPEN
Sbjct  241  NSNVPKFFKIYEQNDIEASTNVNSEFNSLIELLEVNKSGLYSVRDKTYSISLGKLISPEN  300

Query  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360
            YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDW ELPE+QIPE
Sbjct  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWEELPEQQIPE  360

Query  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420
            DKLLRPIISADQANKWSVSL+ +NKKVLYTHEIRD QIKAINLEEFPRAKNYLESHKERL
Sbjct  361  DKLLRPIISADQANKWSVSLIESNKKVLYTHEIRDDQIKAINLEEFPRAKNYLESHKERL  420

Query  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480
            A R YVLKANRNWYEIWVPHDPSLWDKPKIIFPD S EPKFFYEDKGS+VDGNCYWIIPK
Sbjct  421  AGRTYVLKANRNWYEIWVPHDPSLWDKPKIIFPDISSEPKFFYEDKGSIVDGNCYWIIPK  480

Query  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540
            K+N NDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIP+PESIYSKEI
Sbjct  481  KKNDNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPNPESIYSKEI  540

Query  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            ISLV+ELVNNKKE Q+INEIENRIE+LILRAFDIESL
Sbjct  541  ISLVKELVNNKKEAQEINEIENRIEELILRAFDIESL  577


>WP_041639364.1 methyltransferase domain-containing protein [Anoxybacillus flavithermus]
Length=576

 Score = 1095 bits (2831),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 533/576 (93%), Positives = 555/576 (96%), Gaps = 0/576 (0%)

Query  2    MSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAI  61
            MSVQK   VS+QKATGAHFTPDKLAEVIAKRIL+YFKGE+ RVIRVLDPACGDGELLLAI
Sbjct  1    MSVQKVKQVSKQKATGAHFTPDKLAEVIAKRILNYFKGEEKRVIRVLDPACGDGELLLAI  60

Query  62   NKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNI  121
            NKVAQSMNIQLELIGVD DIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN 
Sbjct  61   NKVAQSMNIQLELIGVDSDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNT  120

Query  122  EELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIG  181
            EELEP DIIIANPPYVRTQILGAEKAQ+LR+KFNLKGRVDLYQAFLVAMTQQLKSNGI+G
Sbjct  121  EELEPADIIIANPPYVRTQILGAEKAQQLRKKFNLKGRVDLYQAFLVAMTQQLKSNGIMG  180

Query  182  VITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKEN  241
            VITSNRYLTTKGG S RKFLV NFNILEIMDLGD+KFF+AAVLPAIFFGEKK+KE QKEN
Sbjct  181  VITSNRYLTTKGGESIRKFLVLNFNILEIMDLGDTKFFDAAVLPAIFFGEKKSKENQKEN  240

Query  242  SNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENY  301
            SNVPKFFKIYEQ+DIEAS++VNSEFNSLIELLEVNKSGLYSV DKTYSISLGK+ISPENY
Sbjct  241  SNVPKFFKIYEQNDIEASTNVNSEFNSLIELLEVNKSGLYSVRDKTYSISLGKLISPENY  300

Query  302  KEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPED  361
            KEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDW ELPE+QIPED
Sbjct  301  KEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWEELPEQQIPED  360

Query  362  KLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLA  421
            KLLRPIISADQANKWSVSL+ +NKKVLYTHEIRD QIKAINLEEFPRAKNYLESHKERLA
Sbjct  361  KLLRPIISADQANKWSVSLIESNKKVLYTHEIRDDQIKAINLEEFPRAKNYLESHKERLA  420

Query  422  SRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKK  481
             R YVLKANRNWYEIWVPHDPSLWDKPKIIFPD S EPKFFYEDKGS+VDGNCYWIIPKK
Sbjct  421  GRTYVLKANRNWYEIWVPHDPSLWDKPKIIFPDISSEPKFFYEDKGSIVDGNCYWIIPKK  480

Query  482  ENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEII  541
            +N NDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIP+PESIYSKEII
Sbjct  481  KNDNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPNPESIYSKEII  540

Query  542  SLVRELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            SLV+ELVNNKKE Q+INEIENRIE+LILRAFDIESL
Sbjct  541  SLVKELVNNKKEAQEINEIENRIEELILRAFDIESL  576


>WP_003331201.1 methyltransferase domain-containing protein [Bacillus azotoformans]
 EKN67396.1 adenine-specific DNA methyltransferase [Bacillus azotoformans 
LMG 9581]
Length=580

 Score = 668 bits (1724),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 330/573 (58%), Positives = 432/573 (75%), Gaps = 10/573 (2%)

Query  12   RQKATGAHFTPDKLAEVIAKRILDYFKGEK---NRVIRVLDPACGDGELLLAINKVAQSM  68
            +QK TGAH+TP  L ++IAKR+++  K       + IR LDP+CGDGELLL++N++A+  
Sbjct  11   KQKETGAHYTPTDLGDIIAKRLINELKKSGISGTKKIRGLDPSCGDGELLLSLNRIAKFN  70

Query  69   NI-QLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN--IEELE  125
            NI  +ELIG+D D +AI  A+ RL+  G  + +L   DFLEMV   DN  LF   + ++E
Sbjct  71   NIDNIELIGIDEDKEAIKEADFRLNEMGINDAKLTAGDFLEMVDLEDNLSLFEDELSKIE  130

Query  126  PVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITS  185
            PVD+IIANPPYVRTQ+LGA++AQKL + FNLKGRVDLY AFLVAMT QLK  G+IGVITS
Sbjct  131  PVDLIIANPPYVRTQVLGADRAQKLAKLFNLKGRVDLYHAFLVAMTLQLKPGGLIGVITS  190

Query  186  NRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVP  245
            N+YL    G S R+FL  N++I+EIMDLGD+K F AAVLPAIFFG KK  +  ++ +   
Sbjct  191  NKYLANSSGESIRQFLAENYDIIEIMDLGDTKLFSAAVLPAIFFGRKKENKGIRQTTPA-  249

Query  246  KFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPW  305
             F+KIYE++D  + +    +F +L ELLE + +G+++V++K YS+S GK+I PE++KEPW
Sbjct  250  NFYKIYEETD-PSKTKGTIKFETLFELLESSNTGVFNVDEKFYSVSCGKLIVPESFKEPW  308

Query  306  ILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLR  365
            ++AT++EY W   +N N++  I+D   VKVGIKTTAD VFI+S W ELP+E  PE+++L+
Sbjct  309  VMATDEEYNWITNINNNSFCTIQDLCDVKVGIKTTADKVFIKSTWEELPDEIKPENEVLK  368

Query  366  PIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKY  425
            P++S D A+KW       N+KVLYTHE  +G+ KAI+  ++PRA  YLE+H+E L  RKY
Sbjct  369  PLLSTDHASKWRPLERMPNQKVLYTHENVNGKKKAIDFSKYPRALAYLETHRETLEGRKY  428

Query  426  VLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSN  485
            V+KA RNWYEIWVP +P  W  PKI+FPD SPEPKFFYED+G  +DGNCYWIIPK+EN+N
Sbjct  429  VIKAKRNWYEIWVPQNPDHWALPKIVFPDISPEPKFFYEDEGCCIDGNCYWIIPKEENNN  488

Query  486  DILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVR  545
            DILFLI+GI N+K+M+ YHDIAF NKLYAGRRRYLTQYVNKYP+P+PES YS+EII LVR
Sbjct  489  DILFLILGISNTKYMTNYHDIAFNNKLYAGRRRYLTQYVNKYPLPNPESNYSQEIIELVR  548

Query  546  ELV-NNKKETQDINEIENRIEKLILRAFDIESL  577
            E+V  N  + + I EIEN+IE L   AF +ESL
Sbjct  549  EIVLQNPNDDRKI-EIENQIENLTALAFGVESL  580


>WP_021624002.1 methyltransferase domain-containing protein [Aneurinibacillus 
aneurinilyticus]
 ERI10932.1 site-specific DNA-methyltransferase [Aneurinibacillus aneurinilyticus 
ATCC 12856]
Length=580

 Score = 657 bits (1696),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 323/572 (56%), Positives = 427/572 (75%), Gaps = 8/572 (1%)

Query  12   RQKATGAHFTPDKLAEVIAKRILDYFKGEK---NRVIRVLDPACGDGELLLAINKVAQSM  68
            +QK TGAH+TP  L ++IAKR+++  K       + IR LDP+CGDGELLL++N++A+  
Sbjct  11   KQKETGAHYTPTDLGDIIAKRLINELKKSGISGTKKIRGLDPSCGDGELLLSLNRIAKFN  70

Query  69   NI-QLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN--IEELE  125
            NI  +ELIG+D D +AI  A+ RL+  G  + +L   DFL+MV    N  LF+  + ++E
Sbjct  71   NIDNIELIGIDEDKEAIKEADFRLNEMGINDAKLTAGDFLDMVDLEGNLSLFDDDLSKIE  130

Query  126  PVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITS  185
            PVD+IIANPPYVRTQ+LGA++AQKL + FNLKGRVDLY AFLVAMT QLK  G+IGVITS
Sbjct  131  PVDLIIANPPYVRTQVLGADRAQKLAKLFNLKGRVDLYHAFLVAMTLQLKPGGLIGVITS  190

Query  186  NRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVP  245
            N+YL    G S R+FL  N++I+EIMDLGD+K F AAVLPAIFFG KK  +  ++ +   
Sbjct  191  NKYLANSSGESIRQFLAENYDIIEIMDLGDTKLFSAAVLPAIFFGRKKVNKGIRQTAPA-  249

Query  246  KFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPW  305
             F+KIYE++D  + + V+ +F +L  LLE + +G+++V++K YS+S GK+I P+++KEPW
Sbjct  250  NFYKIYEETD-PSKTEVSIKFETLFGLLESSNTGVFNVDEKFYSVSCGKLIVPDSFKEPW  308

Query  306  ILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLR  365
            ++AT++EY W   +N N+Y  I+D   VKVGIKTTAD VFI+S W ELP+E  PE ++L+
Sbjct  309  VMATDEEYNWITNINNNSYCTIQDLCDVKVGIKTTADKVFIKSTWEELPDEIKPEVEVLK  368

Query  366  PIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKY  425
            P+IS D A+KW       N+K+LYTHE  +G+ KAI+  ++P A  YLE+H+E L  RKY
Sbjct  369  PLISTDHASKWRPLERIPNQKILYTHENVNGKKKAIDFTQYPHALAYLETHRETLEGRKY  428

Query  426  VLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSN  485
            V+KA RNWYEIWVP +P  W  PKI+FPD SPEPKFFYED+G  +DGNCYWIIPK+EN+N
Sbjct  429  VIKAKRNWYEIWVPQNPDHWALPKIVFPDISPEPKFFYEDEGCCIDGNCYWIIPKEENNN  488

Query  486  DILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVR  545
            DILFLI+GI N+K+M+ YHDIAF NKLYAGRRRYLTQYV+KYP+P+PE+ YS+EII LVR
Sbjct  489  DILFLILGISNTKYMTNYHDIAFNNKLYAGRRRYLTQYVSKYPLPNPEANYSQEIIDLVR  548

Query  546  ELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            ELV      +   EIEN+IE L   AF +E L
Sbjct  549  ELVFQNPNDERKIEIENQIENLTALAFGVERL  580


>WP_005831616.1 MULTISPECIES: methyltransferase domain-containing protein [Brevibacillus]
 EJL45207.1 type I restriction-modification system methyltransferase subunit 
[Brevibacillus sp. CF112]
 ELK41519.1 adenine-specific DNA methyltransferase [Brevibacillus agri BAB-2500]
Length=579

 Score = 657 bits (1695),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 325/572 (57%), Positives = 425/572 (74%), Gaps = 9/572 (2%)

Query  12   RQKATGAHFTPDKLAEVIAKRILDYFKGEK---NRVIRVLDPACGDGELLLAINKVAQSM  68
            +QK TGAH+TP  L ++IAKR+++  K       + IR LDP+CGDGELLL++N++A+  
Sbjct  11   KQKETGAHYTPTDLGDIIAKRLINELKKSGVSGTKKIRGLDPSCGDGELLLSLNRIAKFN  70

Query  69   NI-QLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNIE--ELE  125
            NI  +ELIG+D D +AI  A+ RL+  G  + +L   DFLEMV   D+  LF  E  ++E
Sbjct  71   NIDNIELIGIDEDKEAIKEADFRLNEVGINDAKLTVGDFLEMVDLEDD-SLFEGEFSKIE  129

Query  126  PVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITS  185
            PVD+IIANPPYVRTQ+LGA++AQKL + FNLKGRVDLY AFLVAMT QLK  G+IGVITS
Sbjct  130  PVDLIIANPPYVRTQVLGADRAQKLAKLFNLKGRVDLYHAFLVAMTLQLKPGGLIGVITS  189

Query  186  NRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVP  245
            N+YL    G S R+FL  N+NI+EIMDLGD+K F AAVLPAIFFG KK  +  ++ ++  
Sbjct  190  NKYLANSSGESIRQFLAENYNIIEIMDLGDTKLFSAAVLPAIFFGRKKENKGIRQTTSA-  248

Query  246  KFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPW  305
             F+KIYE++D  + +  + +F +L  LLE + +G+++V++K YS+S GK+I PE++KEPW
Sbjct  249  NFYKIYEETD-SSKTEGSIKFETLFGLLESSNTGIFNVDEKFYSVSCGKLIVPESFKEPW  307

Query  306  ILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLR  365
            ++AT +EY W   +N+N++  I+D   VKVGIKTTAD VFI+S W ELP+E  PE ++L+
Sbjct  308  VMATNEEYNWITNINKNSFCTIQDLCDVKVGIKTTADKVFIKSTWEELPDEIKPEAEVLK  367

Query  366  PIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKY  425
            P++S D A+KW       N+KVLYTH+  +G+ KAI+  ++P A  YLE+H+E L  RKY
Sbjct  368  PLLSTDHASKWRPLERRPNQKVLYTHKNVNGKKKAIDFTQYPHALAYLETHRETLEGRKY  427

Query  426  VLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSN  485
            V+KA RNWYEIWVP +P  W  PK++FPD SPEPKFFYED+G  +DGNCYWIIPK+EN+N
Sbjct  428  VIKAKRNWYEIWVPQNPDQWGLPKVVFPDISPEPKFFYEDEGCCIDGNCYWIIPKEENNN  487

Query  486  DILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVR  545
            DILFLI+GI N+K+M+ YHDIAF NKLYAGRRRYLTQYVNKYP+P+PES YS+EII LVR
Sbjct  488  DILFLILGISNTKYMTNYHDIAFNNKLYAGRRRYLTQYVNKYPLPNPESNYSQEIIDLVR  547

Query  546  ELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            ELV          EIEN IE L   AF +E L
Sbjct  548  ELVFQNPNNARKVEIENHIENLTALAFGVERL  579


>WP_111948994.1 methyltransferase domain-containing protein [Dolosigranulum pigrum]
 RAN55763.1 modification methylase [Dolosigranulum pigrum]
Length=572

 Score = 651 bits (1680),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 309/564 (55%), Positives = 418/564 (74%), Gaps = 6/564 (1%)

Query  14   KATGAHFTPDKLAEVIAKRIL-DYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQL  72
            K TG+HFTP  LA+ IA ++L +Y     N+ IRVLDPACGDGELL++I K+A+ + + L
Sbjct  10   KETGSHFTPASLADFIANKLLNEYQNSNTNKTIRVLDPACGDGELLISICKIARELKLDL  69

Query  73   ELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN--IEELEPVDII  130
            E+IGVD + +AI I   RL   G  N++L+N DFLE+V    + ++FN  + ++ PVDII
Sbjct  70   EVIGVDSNEEAIEITRTRLEDLGFNNYKLMNNDFLEIVDNYLDLNIFNESVNDISPVDII  129

Query  131  IANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRYLT  190
            IANPPYVRTQ+LGA+KAQ+L +KF L+GRVDLYQ FLVAMT+ LK NG IGVITSNRYL 
Sbjct  130  IANPPYVRTQVLGADKAQELGKKFGLRGRVDLYQIFLVAMTELLKINGTIGVITSNRYLN  189

Query  191  TKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFFKI  250
            TKGG S RKFLVSN+++ +I DLGD+KFF AAVLPAIFFG K +          P+F KI
Sbjct  190  TKGGKSIRKFLVSNYDMDKIYDLGDTKFFSAAVLPAIFFGTKVSTPENLLEKQSPEFLKI  249

Query  251  YEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWILATE  310
            YE+   +    V ++    I+LL + + G YS+ D TY +  GKI+SPENY EPW++A++
Sbjct  250  YEE---QTDKEVIADLEEKIDLLHLTQPGFYSIGDITYEVITGKIVSPENYNEPWVMASK  306

Query  311  DEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPIISA  370
            +EY+W  K+N  + G I+D+A V+VG+KTTAD VFI S+W  L  +  PE+ LL P++SA
Sbjct  307  EEYKWISKINNLSAGRIDDYAKVRVGVKTTADKVFISSEWDNLDTKLTPENDLLYPLVSA  366

Query  371  DQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLKAN  430
            + A KW+V L  + KK+LY H + DG+   ++L ++P++K YLESH+ +L  RKYV+KAN
Sbjct  367  ENAEKWTVDLTDHTKKILYPHMVVDGKRSTVDLNKYPKSKQYLESHRVQLEGRKYVIKAN  426

Query  431  RNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDILFL  490
            R W+EIWVPHDP  W KPK++ PD S E KFFY++KG +VDGNCYWI+PKK+N ++ILFL
Sbjct  427  RKWFEIWVPHDPDSWIKPKVVLPDISTEAKFFYDEKGVIVDGNCYWILPKKDNDSEILFL  486

Query  491  IMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRELVNN  550
            IMG+ NSKFM KYHDIA+QNKLY+GRRRYLTQYV  YP+P+P+SIY++ II LV+ +V +
Sbjct  487  IMGMANSKFMRKYHDIAYQNKLYSGRRRYLTQYVKNYPLPNPDSIYAQNIIKLVKNIVFD  546

Query  551  KKETQDINEIENRIEKLILRAFDI  574
              ++ ++ + E +IE  I + FD+
Sbjct  547  SLDSNEVEKYEEKIENEIGKYFDL  570


>P22772.1 RecName: Full=Modification methylase BanIII; Short=M.BanIII; 
AltName: Full=Adenine-specific methyltransferase BanIII
Length=580

 Score = 648 bits (1671),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 320/572 (56%), Positives = 424/572 (74%), Gaps = 8/572 (1%)

Query  12   RQKATGAHFTPDKLAEVIAKRILDYFKGEK---NRVIRVLDPACGDGELLLAINKVAQSM  68
            +QK TGAH+TP  L ++IAKR+++  K       + IR LDP+CGDGELLL++N++A+  
Sbjct  11   KQKETGAHYTPTDLGDIIAKRLINELKKSGISGTKKIRGLDPSCGDGELLLSLNRIAKFN  70

Query  69   NI-QLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN--IEELE  125
            NI  +ELIG+D D +AI  A+ RL+  G  + +L   DFL+MV    N  LF+  + ++E
Sbjct  71   NIDNIELIGIDEDKEAIKEADFRLNEMGINDAKLTAGDFLDMVDLEGNLSLFDDDLSKIE  130

Query  126  PVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITS  185
            PVD+IIANPPYVRTQ+LGA++AQKL + FNLKGRVDLY AFLVAMT QLK  G+IGVITS
Sbjct  131  PVDLIIANPPYVRTQVLGADRAQKLAKLFNLKGRVDLYHAFLVAMTLQLKPGGLIGVITS  190

Query  186  NRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVP  245
            N+YL    G S R+FL  N++I+EIMDLGD+K F AAVL AIFFG KK  +  ++ +   
Sbjct  191  NKYLANSSGESIRQFLAENYDIIEIMDLGDTKLFSAAVLQAIFFGRKKVNKGIRQTAPA-  249

Query  246  KFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPW  305
             F+KIYE++D  + + V+ +F +L  LLE + +G+++V++K YS+S GK+I P+++KEPW
Sbjct  250  NFYKIYEETD-PSKTEVSIKFETLFGLLESSNTGVFNVDEKFYSVSCGKLIVPDSFKEPW  308

Query  306  ILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLR  365
            ++AT++EY W   +N N+Y  I+D   VKVGIKTTAD VFI+S W ELP+E  PE ++L+
Sbjct  309  VMATDEEYNWITNINNNSYCTIQDLCDVKVGIKTTADKVFIKSTWEELPDEIKPEVEVLK  368

Query  366  PIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKY  425
             +IS D A+KW       N+K+LYTHE  +G+ KAI+  ++P A  YLE+H+E L  RKY
Sbjct  369  LLISTDHASKWRPLERIPNQKILYTHENVNGKKKAIDFTQYPHALAYLETHRETLEGRKY  428

Query  426  VLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSN  485
            V+KA RNWYEIWVP +P  W  PKI+FPD SPEPKFFYED+G  +DGNCYWIIPK+EN+N
Sbjct  429  VIKAKRNWYEIWVPQNPDHWALPKIVFPDISPEPKFFYEDEGCCIDGNCYWIIPKEENNN  488

Query  486  DILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVR  545
            DILFLI+GI N+K+M+ YHDIAF NKLY GRRRYLTQYV+KYP+P+PE+ YS+EII LVR
Sbjct  489  DILFLILGISNTKYMTNYHDIAFNNKLYPGRRRYLTQYVSKYPLPNPEANYSQEIIDLVR  548

Query  546  ELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            ELV      +   EIEN+IE L   AF +E L
Sbjct  549  ELVFQNPNDERKIEIENQIENLTALAFGVERL  580


>WP_110899598.1 methyltransferase domain-containing protein [Paenibacillus barcinonensis]
 PYE42684.1 TaqI restriction endonuclease [Paenibacillus barcinonensis]
Length=574

 Score = 622 bits (1603),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 312/575 (54%), Positives = 414/575 (72%), Gaps = 16/575 (3%)

Query  9    TVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSM  68
            T  +QKATG+H+TP  LA V+A+R+L   K E +R + VLDP+CGDGELLLAI    +S 
Sbjct  5    TTDKQKATGSHYTPTGLATVLARRLLSEVK-ENDRALNVLDPSCGDGELLLAI--AEESK  61

Query  69   NIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNIEELEP--  126
            + +L LIGV+ + DAI  + +R + +  K   LI  D+LEMV+  ++ DLFN  E E   
Sbjct  62   DHKLNLIGVEENDDAIQDSMKRFTDTEIKEVTLIKNDYLEMVNLDNHVDLFNFNESESND  121

Query  127  -VDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITS  185
             VDIIIANPPYVRTQILGAEKAQ L EKFNL GRVDLY AFLVAMT QL   G++GVITS
Sbjct  122  LVDIIIANPPYVRTQILGAEKAQMLSEKFNLSGRVDLYHAFLVAMTSQLPIGGLLGVITS  181

Query  186  NRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVP  245
            NRYLTT GG + R+FL  N+ I+EIMDLGD+K F AAVLPAIF G KK+K  + +N++  
Sbjct  182  NRYLTTTGGTAIRQFLDENYEIIEIMDLGDTKLFSAAVLPAIFIGRKKHKNDKTKNNDNA  241

Query  246  KFFKIYE-----QSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPEN  300
            KFF+IYE     + DIE ++      NS+ E+LEV +SG+Y  E K Y +SLG++  P++
Sbjct  242  KFFRIYEAVEEARLDIETNT-----VNSIFEILEVKQSGIYEAEGKKYKVSLGELDIPKS  296

Query  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360
            YKEPW++A+ DE  W  K+ QN+   IED A V+VGIKTTAD VFI++ W +   E  PE
Sbjct  297  YKEPWVMASLDEQIWIDKIKQNSKYLIEDVAKVRVGIKTTADPVFIKNGWEDSSNEIQPE  356

Query  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420
             +LLR ++S+D A+KW         +VLYTH++ +G+   I+  ++P+A +YLE+H+ERL
Sbjct  357  KELLRHLLSSDHASKWRPIEKRPALRVLYTHKVENGRRTVIDFSQYPKALSYLETHRERL  416

Query  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480
              RKYV+KA R W+EIWVPHDP+ W K K++FPD SPEPKFF + +G +VDGN YWI   
Sbjct  417  EGRKYVIKAKRKWFEIWVPHDPNSWGKLKVVFPDISPEPKFFLDTEGCIVDGNSYWITLN  476

Query  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540
            +  S DILFLI+ I N++ M+KYHDI+FQNKLY+GRRRYLTQYV KYPIP+PE+ Y+K++
Sbjct  477  EGFSEDILFLILAISNTRLMTKYHDISFQNKLYSGRRRYLTQYVEKYPIPNPETEYAKKL  536

Query  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDIE  575
            +SL +ELV  +   + + EIEN+IE    +AF++E
Sbjct  537  VSLSKELVYKENNLEKVKEIENKIEYYSAKAFNVE  571


>WP_017474986.1 MULTISPECIES: methyltransferase [Bacteria]
 KUL09346.1 modification methylase [Bacillus licheniformis LMG 17339]
 KYC79824.1 hypothetical protein B4091_0947 [Bacillus licheniformis]
 KYC82503.1 hypothetical protein B4090_1142 [Bacillus licheniformis]
 KYC94031.1 hypothetical protein B4164_1332 [Bacillus licheniformis]
 AMR09494.1 modification methylase [Bacillus licheniformis]
 SEQ58148.1 TaqI-like C-terminal specificity domain-containing protein [Bacillus 
licheniformis]
 OJT55224.1 modification methylase [Bacillus licheniformis]
 OJT68234.1 modification methylase [Bacillus licheniformis]
 PLS10567.1 modification methylase [Bacillus licheniformis]
 AWV39759.1 modification methylase [Bacillus licheniformis]
 RIU96794.1 methyltransferase [Bacillus licheniformis]
 AZN80442.1 modification methylase [Bacillus licheniformis]
Length=577

 Score = 567 bits (1461),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 293/580 (51%), Positives = 399/580 (69%), Gaps = 24/580 (4%)

Query  9    TVSRQKATGAHFTPDKLAEVIAKRILDY--FKGEKNRVIRVLDPACGDGELLLAINKVAQ  66
            +++ +K TG+H+T   L++ +AK++L Y  F G   R   +LDP+CGDGELL AI     
Sbjct  4    SLAERKETGSHYTSSYLSKYMAKKLLKYAEFDGSGERQ-SILDPSCGDGELLKAICNEIG  62

Query  67   SMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLF-------  119
            + N  LE+IG+D D +A++ A+  LS S + N  L N D+LE+      YDLF       
Sbjct  63   TEN--LEVIGMDTDKEAVHNASNSLSASNNSNIHLFNNDYLELFEGDTEYDLFSEIKKRE  120

Query  120  ------NIEE-LEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQ  172
                  N E+ L+ VD+IIANPPYVRTQ+LGA+KAQ L  KFNLKGRVDLY  FLVAMT+
Sbjct  121  DFWCSKNEEDGLKKVDMIIANPPYVRTQVLGADKAQDLGSKFNLKGRVDLYHVFLVAMTK  180

Query  173  QLKSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEK  232
             LK NG++ VITSNRYLTT GG   RKFL  N+ ILE++DLGD+K FEAAVLPAIF G K
Sbjct  181  HLKENGLLCVITSNRYLTTAGGKDIRKFLDENYEILEVIDLGDTKLFEAAVLPAIFIGRK  240

Query  233  KNKEYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISL  292
            K+K+  K N  V KFF+IYE   IE +     E +SL E+L    SG +  + K Y +++
Sbjct  241  KSKDETKNNDKV-KFFRIYENPTIETAE----ECSSLFEILSKEGSGFFEADKKKYEVTV  295

Query  293  GKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGE  352
            G +  PEN KE W++A++++ EW  KV   A  F +D  HV+VGIKTTAD VFI+++W  
Sbjct  296  GFLKVPENPKELWVMASKEDNEWSDKVKSRAEYFFKDVFHVRVGIKTTADKVFIKNNWDT  355

Query  353  LPEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNY  412
            L +  IPE+++L+P+IS+D  +KW++     N K+LYTHE+++G+ +AI+LE++P+AK Y
Sbjct  356  LEDFMIPENEVLKPLISSDYTSKWNLPNEVENLKILYTHEVKNGKRQAIDLEKYPKAKAY  415

Query  413  LESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDG  472
            LESHKE LA RKYV+KA RNWYEIWVP +P  W  PK++FPD S EPKF  +  G +VDG
Sbjct  416  LESHKEVLAGRKYVIKAKRNWYEIWVPQNPDAWSLPKVVFPDISSEPKFAIDTNGYLVDG  475

Query  473  NCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDP  532
            NCYW+  K + + D+L+L + + NSKFM+K+H+I FQNKLYAGR+RYLTQYV  YP+PDP
Sbjct  476  NCYWLSLKNDENTDLLYLAVAVANSKFMTKFHEIEFQNKLYAGRKRYLTQYVENYPLPDP  535

Query  533  ESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAF  572
             S++S+ ++ L + L  N    ++I   E  IE  + +AF
Sbjct  536  NSVHSQRLVELAKILTTNGLSEEEIKTYETEIETEVQQAF  575


>CAA58443.1 methyltransferase [Aneurinibacillus aneurinilyticus]
Length=505

 Score = 549 bits (1415),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 267/496 (54%), Positives = 366/496 (74%), Gaps = 8/496 (2%)

Query  12   RQKATGAHFTPDKLAEVIAKRILDYFKGEK---NRVIRVLDPACGDGELLLAINKVAQSM  68
            +QK TGAH+TP  L ++IAKR+++  K       + IR LDP+CGDGELLL++N++ +  
Sbjct  11   KQKETGAHYTPTDLGDIIAKRLINELKKSGISGTKKIRGLDPSCGDGELLLSLNRMGKFN  70

Query  69   NI-QLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN--IEELE  125
            NI  +ELIG+D D +AI  A+ RL+  G  + +L   DFL+MV    N  LF+  + ++E
Sbjct  71   NIDNIELIGIDEDKEAIKEADFRLNEMGINDAKLSGGDFLDMVDLEGNLSLFDDDLSKIE  130

Query  126  PVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITS  185
            PVD+IIANPPYVRTQ+LGA++AQKL + FNLKGRVDLY AFLVAMT QLK  G+IGVITS
Sbjct  131  PVDLIIANPPYVRTQVLGADRAQKLAKLFNLKGRVDLYHAFLVAMTLQLKPGGLIGVITS  190

Query  186  NRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVP  245
            N+YL    G S R+FL  N++I+EIMDLGD+K F  AVL AIFFG KK  +  ++ +   
Sbjct  191  NKYLANTTGESIRQFLAENYDIIEIMDLGDTKLFSGAVLQAIFFGTKKLNKGIRQTAPA-  249

Query  246  KFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPW  305
             F+KIYE++D  + + V+ +F +L  LLE + +G+++V++K YS+S GK+I P+++KEPW
Sbjct  250  NFYKIYEETD-PSKTEVSIKFETLFGLLESSNTGVFNVDEKFYSVSCGKLIVPDSFKEPW  308

Query  306  ILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLR  365
            ++AT++EY W   +N N+Y  I+D   +KVGIKTTAD VFI+S W ELP+E  PE ++L+
Sbjct  309  VMATDEEYNWITNINNNSYCTIQDLCDLKVGIKTTADKVFIKSTWEELPDEIKPEVEVLK  368

Query  366  PIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKY  425
             +IS D A+KW       N+K+LYTHE  +G+ KAI+  ++P A  YLE+H+E L  RKY
Sbjct  369  LLISTDHASKWRPLERIGNQKILYTHENLNGKKKAIHFTQYPHALAYLETHRETLEGRKY  428

Query  426  VLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSN  485
            V+KA RNWY+IW+P +P  W  PKI+FPD SPEPKFFYED+G  +DGNCYWIIPK+EN+N
Sbjct  429  VIKAKRNWYQIWLPQNPDHWALPKILFPDISPEPKFFYEDEGCCIDGNCYWIIPKEENNN  488

Query  486  DILFLIMGICNSKFMS  501
            DILFLI+GI N+K+M+
Sbjct  489  DILFLILGISNTKYMT  504


>WP_134157076.1 methyltransferase domain-containing protein [Bacillus subtilis]
Length=576

 Score = 546 bits (1407),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 287/575 (50%), Positives = 384/575 (67%), Gaps = 25/575 (4%)

Query  14   KATGAHFTPDKLAEVIAKRILDY--FKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQ  71
            K TG+H+T  +L++ +A+++L+             VLDP+CGDGELL A     +S N  
Sbjct  9    KETGSHYTSGELSKFMARKLLEQVELNNSTEDYQTVLDPSCGDGELLKAF--FQESNNQN  66

Query  72   LELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLF------------  119
            LE+IG+D + +AIN A + L+   ++N  L N D+LE+ +E  N DLF            
Sbjct  67   LEVIGMDTNREAINSARQHLNADDNENIHLFNGDYLELFTES-NPDLFSEVLVREDYWSS  125

Query  120  NIEE--LEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSN  177
            N EE  L+ VD+IIANPPYVRTQ+LG EK+Q L +KFNLKGRVDLY  FLVAMTQ LK N
Sbjct  126  NTEEDGLKKVDMIIANPPYVRTQVLGGEKSQDLGKKFNLKGRVDLYHVFLVAMTQHLKEN  185

Query  178  GIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEY  237
            G+I VITSNRYLTT GG   RKFL  N+ I+E++DLGD+K F+AAVLPAIF G +K    
Sbjct  186  GLICVITSNRYLTTAGGKDIRKFLDENYEIIEVIDLGDTKLFDAAVLPAIFIG-RKKANK  244

Query  238  QKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIIS  297
             K+ ++  KF++IYE S +E +   +S F    E+L    SG Y    K Y +++G +  
Sbjct  245  DKKKNDKVKFYRIYENSSLEDTEKCDSIF----EILLKKDSGSYETNGKKYEVTVGYLKI  300

Query  298  PENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQ  357
            PE+ KE W++A++++  W   V   A    ED  +V+VGIKTTADSVFIR DW +L +  
Sbjct  301  PEDSKELWVMASKEDNLWSEIVKSQAKYKFEDVFNVRVGIKTTADSVFIRDDWDKLDDSM  360

Query  358  IPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHK  417
            IPE +LL+P+ S+D ANKW +  + +N K+LYTHE+ DG+ KAI+LE++P+AK YLESH+
Sbjct  361  IPESELLKPLASSDTANKWVLPQL-DNTKILYTHEVVDGKRKAIDLEQYPKAKAYLESHR  419

Query  418  ERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWI  477
            ERL  R YV+KA RNWYEIWVP DPS W  PK+IFPD S EPKF  +    +VDGNCYW+
Sbjct  420  ERLEGRSYVIKAKRNWYEIWVPQDPSKWTLPKVIFPDISSEPKFAVDTNDYLVDGNCYWL  479

Query  478  IPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYS  537
              K E + D+L+L + + NS  MSK+H I FQN LYAGR+RYLTQYV  YP+PDP S +S
Sbjct  480  SLKDEENTDLLYLAVAVANSCLMSKFHGIEFQNMLYAGRKRYLTQYVKNYPLPDPNSTHS  539

Query  538  KEIISLVRELVNNKKETQDINEIENRIEKLILRAF  572
            + +I + +EL +N     +I   E  IE  + +AF
Sbjct  540  QRLIEIAKELTHNDLSEDEIKRYEAEIETEVNQAF  574


>TDY53733.1 TaqI restriction endonuclease [Bacillus subtilis]
Length=585

 Score = 545 bits (1405),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 287/575 (50%), Positives = 384/575 (67%), Gaps = 25/575 (4%)

Query  14   KATGAHFTPDKLAEVIAKRILDY--FKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQ  71
            K TG+H+T  +L++ +A+++L+             VLDP+CGDGELL A     +S N  
Sbjct  18   KETGSHYTSGELSKFMARKLLEQVELNNSTEDYQTVLDPSCGDGELLKAF--FQESNNQN  75

Query  72   LELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLF------------  119
            LE+IG+D + +AIN A + L+   ++N  L N D+LE+ +E  N DLF            
Sbjct  76   LEVIGMDTNREAINSARQHLNADDNENIHLFNGDYLELFTES-NPDLFSEVLVREDYWSS  134

Query  120  NIEE--LEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSN  177
            N EE  L+ VD+IIANPPYVRTQ+LG EK+Q L +KFNLKGRVDLY  FLVAMTQ LK N
Sbjct  135  NTEEDGLKKVDMIIANPPYVRTQVLGGEKSQDLGKKFNLKGRVDLYHVFLVAMTQHLKEN  194

Query  178  GIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEY  237
            G+I VITSNRYLTT GG   RKFL  N+ I+E++DLGD+K F+AAVLPAIF G +K    
Sbjct  195  GLICVITSNRYLTTAGGKDIRKFLDENYEIIEVIDLGDTKLFDAAVLPAIFIG-RKKANK  253

Query  238  QKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIIS  297
             K+ ++  KF++IYE S +E +   +S F    E+L    SG Y    K Y +++G +  
Sbjct  254  DKKKNDKVKFYRIYENSSLEDTEKCDSIF----EILLKKDSGSYETNGKKYEVTVGYLKI  309

Query  298  PENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQ  357
            PE+ KE W++A++++  W   V   A    ED  +V+VGIKTTADSVFIR DW +L +  
Sbjct  310  PEDSKELWVMASKEDNLWSEIVKSQAKYKFEDVFNVRVGIKTTADSVFIRDDWDKLDDSM  369

Query  358  IPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHK  417
            IPE +LL+P+ S+D ANKW +  + +N K+LYTHE+ DG+ KAI+LE++P+AK YLESH+
Sbjct  370  IPESELLKPLASSDTANKWVLPQL-DNTKILYTHEVVDGKRKAIDLEQYPKAKAYLESHR  428

Query  418  ERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWI  477
            ERL  R YV+KA RNWYEIWVP DPS W  PK+IFPD S EPKF  +    +VDGNCYW+
Sbjct  429  ERLEGRSYVIKAKRNWYEIWVPQDPSKWTLPKVIFPDISSEPKFAVDTNDYLVDGNCYWL  488

Query  478  IPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYS  537
              K E + D+L+L + + NS  MSK+H I FQN LYAGR+RYLTQYV  YP+PDP S +S
Sbjct  489  SLKDEENTDLLYLAVAVANSCLMSKFHGIEFQNMLYAGRKRYLTQYVKNYPLPDPNSTHS  548

Query  538  KEIISLVRELVNNKKETQDINEIENRIEKLILRAF  572
            + +I + +EL +N     +I   E  IE  + +AF
Sbjct  549  QRLIEIAKELTHNDLSEDEIKRYEAEIETEVNQAF  583


>PYV21223.1 modification methylase [Acidobacteria bacterium]
Length=589

 Score = 544 bits (1401),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 272/587 (46%), Positives = 387/587 (66%), Gaps = 14/587 (2%)

Query  1    MMSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA  60
            MM       V+++KATGAHFTP  LA ++ +R+L     E+N  +RVLDP+CGDG+LL A
Sbjct  1    MMQALAKCAVAQRKATGAHFTPPDLAALLGRRLLAQDLAEENGEVRVLDPSCGDGQLLKA  60

Query  61   I-NKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMV-SEGDNYDL  118
            + +    S+  +++LIGV+ D  ++  A + LS +      L+  DFL +  S      L
Sbjct  61   LYDASPSSLRAKIQLIGVESDALSLERARDVLSVARDDRLVLVQGDFLSLAASPQGELPL  120

Query  119  FNIEE-----LEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQ  173
            F          +P  +IIANPPYVRTQILG++++Q+L   F L GR+DLY AFLVAMT+Q
Sbjct  121  FAPSSGTCGLRDPAHVIIANPPYVRTQILGSDQSQRLAATFGLAGRIDLYHAFLVAMTRQ  180

Query  174  LKSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKK  233
            L   G++GVITSNR+LTT+GG S R FL   F I+EI+DLGD+K FEAAVLPA+F G ++
Sbjct  181  LVPGGLLGVITSNRFLTTRGGQSVRDFLRREFEIIEILDLGDTKLFEAAVLPAVFIGRRR  240

Query  234  NKEYQKENSNVP--KFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSIS  291
               ++   +  P  KF +IYEQ +   S S+  +  S+ ELL+V K+G Y+V  + ++  
Sbjct  241  KGPHRHSVATPPVAKFVRIYEQCEQSDSLSIK-QARSVCELLDVPKAGPYTVGSRRFT--  297

Query  292  LGKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWG  351
             G++  P    EPW + TE E +W  ++  N+   +  FA V+VG+K+TAD VFIR+DW 
Sbjct  298  -GELCLPSRASEPWSMLTEGEQKWMTRLTSNSQHRVSQFAKVRVGVKSTADEVFIRADWH  356

Query  352  ELPEEQIPEDKLLRPIISADQANKWSVSLVGNN-KKVLYTHEIRDGQIKAINLEEFPRAK  410
             LPE+  PE ++L PI+S  +A  W   L   + +++LYTHE++ G+ + I++  FPRA 
Sbjct  357  MLPEDIRPESEILFPILSHREAAPWRPLLPDKHARRILYTHEVKHGKRRCIDISRFPRAA  416

Query  411  NYLESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVV  470
             YLESHK RLA R+YV +ANR WYEIWVP DP  W+ PKI+FPD S EP+FF++ +G +V
Sbjct  417  AYLESHKNRLARRQYVAEANRLWYEIWVPQDPRAWNLPKIVFPDISAEPRFFFDGEGRLV  476

Query  471  DGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIP  530
            DG+CYWI  ++    D+LFLIM + NS  M++YHD+AFQNKLY+GRRRY TQ+V KYP+P
Sbjct  477  DGDCYWITLREGVHEDVLFLIMALANSHLMARYHDLAFQNKLYSGRRRYFTQFVEKYPLP  536

Query  531  DPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            DP S  ++ ++   +EL  N   T+  N+I + IE+L L AF +E +
Sbjct  537  DPASNEARRLVLSAKELAFNVLPTEQGNKILSEIEQLALAAFRVEPV  583


>PSQ89734.1 modification methylase [Bacteroidetes bacterium QS_8_64_10]
Length=584

 Score = 536 bits (1382),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 262/568 (46%), Positives = 370/568 (65%), Gaps = 10/568 (2%)

Query  13   QKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKV-AQSMNIQ  71
            +K TGAHFTP  L+  +A++ILD    +    I VLDPACG G+LL A  +V  + +  +
Sbjct  10   KKETGAHFTPRPLSLFLARKILDAACLKDEGEISVLDPACGKGQLLSAFVRVIPERLRER  69

Query  72   LELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDN-YDLFNIEELEP-VDI  129
             +LIG++ + D++  A +RL+    K   L   DFLE+ ++ +N  DLF+     P V +
Sbjct  70   TKLIGIETNADSLARAEQRLAGLATKEVDLQQADFLELCAQDENNSDLFSGAPAVPSVHV  129

Query  130  IIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRYL  189
            +IANPPYVRTQ+LGAE+++KL   F LKG++DLYQAFLV MTQ+L   G+IGVITSNR+L
Sbjct  130  VIANPPYVRTQVLGAERSRKLASSFGLKGKLDLYQAFLVGMTQRLAPGGVIGVITSNRFL  189

Query  190  TTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFFK  249
            +TK G +TR+ L   ++I  + DLGD+K F+AAVLP++F G +K   + +     P+F K
Sbjct  190  STKSGATTRRLLAQEYDIEAVYDLGDTKLFDAAVLPSVFVGTRKPSPHDERE---PQFLK  246

Query  250  IYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWILAT  309
            IY  SD   S   +   +S+ +LL+  ++G +SV  +T+S+S G +  P +  EPW L T
Sbjct  247  IY-GSDNSHSEEESERVDSVYDLLDEERNGCFSVGSRTFSVSSGTLALPPDPSEPWSLIT  305

Query  310  EDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPIIS  369
            +DE  W   +         D   V+VGIKT AD VF+  DW  L  E  PEDKLLR +++
Sbjct  306  DDEAAWLQSIEDQTTCRFGDLVDVRVGIKTNADEVFVGQDWSTL--EAKPEDKLLRCLLT  363

Query  370  ADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLKA  429
            +D A++W V       +VLYTHE+R+G  KAINL++ PRA  YLE H++RL  R Y+L+A
Sbjct  364  SDCADRW-VPRQTQKPRVLYTHEVRNGDRKAINLDDHPRAAAYLEHHRKRLEKRTYLLEA  422

Query  430  NRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDILF  489
            NRNW+EIWVP DPS W +PKI+FPD S EPKFFY+D+  +V GNCYW         D+LF
Sbjct  423  NRNWFEIWVPQDPSAWSRPKIVFPDISAEPKFFYDDQQCIVKGNCYWFTLAPNRDKDLLF  482

Query  490  LIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRELVN  549
            L+ GI NS+  ++YHD+ F NKLYAGRRRYLTQYV  YP+P  +S  +K+II++ +EL  
Sbjct  483  LLQGIANSQLATRYHDLRFNNKLYAGRRRYLTQYVKTYPVPRLDSTGAKQIIAMAKELTF  542

Query  550  NKKETQDINEIENRIEKLILRAFDIESL  577
               + +    +E  +E+ + RAF ++ L
Sbjct  543  RATDGEKRRSLEQELEEAVARAFGVQPL  570


>WP_098331187.1 methyltransferase domain-containing protein [Bacillus cereus]
 PFC99698.1 modification methylase [Bacillus cereus]
Length=579

 Score = 525 bits (1352),  Expect = 4e-178, Method: Compositional matrix adjust.
 Identities = 276/578 (48%), Positives = 385/578 (67%), Gaps = 28/578 (5%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFK---GEKNRVIRVLDPACGDGELLLAI-NKVAQSMN  69
            K TG+H+T ++L+  +AK++L Y +     +  ++ VLDP+CG GELL AI N+V  +  
Sbjct  9    KETGSHYTSNELSRYMAKKLLKYAEIDNHSEQEMLSVLDPSCGSGELLKAICNEVDTT--  66

Query  70   IQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNI--------  121
             +LE+IG+D D  AI  A + L  + + N  L N D+LE+    D  DLF+         
Sbjct  67   -KLEIIGMDTDESAILQATDYLDANNNSNINLFNGDYLELFDNNDG-DLFSDVTVRDDFW  124

Query  122  ------EELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLK  175
                  + L+ VD+IIANPPYVRTQ+LGAEKAQ L EKF LKGRVDLY  FLVAMT+QLK
Sbjct  125  CSDTEGDGLKKVDMIIANPPYVRTQVLGAEKAQDLGEKFGLKGRVDLYHVFLVAMTRQLK  184

Query  176  SNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNK  235
             +G+I VITSNRYLTT GG   RKFL  ++ +LE++DLGD+K F+AAVLPAIF G KK+ 
Sbjct  185  EDGLICVITSNRYLTTAGGKDIRKFLDDHYEVLEVIDLGDTKLFDAAVLPAIFIGRKKSN  244

Query  236  EYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKI  295
            +  K N+NV KF +IYE S    S++   +  S+ E+L   +SG +    K Y +++G +
Sbjct  245  KDIKANNNV-KFLRIYENS----SANNTEKCGSIYEMLWKTESGFFETNVKKYEVTVGYL  299

Query  296  ISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPE  355
              P++ KE W++A++++  W  +V   A     D  +V+VGIKTTADSVFIR DW  L +
Sbjct  300  KIPQDSKELWVMASKEDVLWSTRVKSQAKYIFNDVFNVRVGIKTTADSVFIREDWDALDD  359

Query  356  EQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLES  415
               PE++LL+P++S+    KW+ S      K+LYTHE+++G+ +AI+LE++P+AK YLE+
Sbjct  360  SLKPEEELLKPLVSSSTVGKWAFSNQVERLKILYTHEVKNGKRQAIDLEQYPKAKAYLET  419

Query  416  HKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCY  475
            H+ERL  RKYV+ A RNWYEIWVP DP     PK++FPD SP PKF  +  G  VDGNCY
Sbjct  420  HRERLEGRKYVIAAKRNWYEIWVPQDPKALSAPKVVFPDISPAPKFSVDTNGYFVDGNCY  479

Query  476  WIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESI  535
            WI    + S D+L+L   + NS+FM K+H+I FQN+LYAGR+RYLTQYV  YP+PDP S+
Sbjct  480  WITLGNDQSTDLLYLATVVANSEFMCKFHEIEFQNQLYAGRKRYLTQYVGNYPLPDPNSV  539

Query  536  YSKEIISLVRELVNNKK-ETQDINEIENRIEKLILRAF  572
            +S+++I + + L +N     ++I   E  IE  I +AF
Sbjct  540  HSQKLIEIGKILTHNTTLNEEEIKVYETEIESEIKQAF  577


>WP_133391247.1 modification methylase [Algoriphagus sp. F21]
 TDK43566.1 modification methylase [Algoriphagus sp. F21]
Length=575

 Score = 515 bits (1326),  Expect = 2e-174, Method: Compositional matrix adjust.
 Identities = 262/574 (46%), Positives = 378/574 (66%), Gaps = 20/574 (3%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQLE  73
            K+TGA FTP  LA+ +A  I+ Y   + +  + VLDP+CGDGELLLAIN+V +   +   
Sbjct  8    KSTGATFTPQGLADFLASEIVKYVDTDTD--LTVLDPSCGDGELLLAINRVLEDTRLNYS  65

Query  74   LIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGD---NYDLFNIEELEPV---  127
            L G D +   ++ A  RL        RL   DFLE+V   D   +    + +EL  V   
Sbjct  66   LRGFDTNQTYLDEAYARLELIDPNKVRLEQGDFLELVDLSDEQLSLGFGDSKELSSVNCS  125

Query  128  -DIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSN  186
             DIIIANPPYVRTQILG++K+Q+L +KFNLKGRVDLY  FL++MT+ LK  GI+GVITSN
Sbjct  126  ADIIIANPPYVRTQILGSQKSQELAKKFNLKGRVDLYYPFLISMTESLKEGGILGVITSN  185

Query  187  RYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPK  246
            RYL+TKGG S RK+LV N+ ILE++DLGD+K F+AAVLPAIF G K+    +++     +
Sbjct  186  RYLSTKGGESIRKYLVDNYEILEVIDLGDTKLFDAAVLPAIFIGRKRRVGSKQKVKKEAQ  245

Query  247  FFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWI  306
            F KIYE+  +   +   ++ NS+ E+L+  +SG +++ +K Y  + G +    N    W 
Sbjct  246  FIKIYEE--LNGYNGDLTQVNSVYEILKNPESGYFNIGNKRYKRTNGLLKYEANSGSTWQ  303

Query  307  LATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRP  366
            + ++ E  W   + +N+ GF+ DF  V+VGIKTTAD VFI  DWG+L  +  PE +LL+ 
Sbjct  304  MLSKSELAWASLIQKNSKGFVGDFFKVRVGIKTTADKVFISDDWGKLGSDS-PEKELLKD  362

Query  367  IISADQANKWSVSLVGNNK---KVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASR  423
            +IS +  ++W V    N+K   KVLYTHE+ +G+ + IN++++P AK Y   H E+L  R
Sbjct  363  LISQENIDRWRV----NDKVDLKVLYTHELVEGKKETINIDKYPLAKQYFLKHSEQLKGR  418

Query  424  KYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKEN  483
            KYV+ + R W+EIWVP +P  W  PK++FPD S  P+F+++  G +V+GNCYWI+ +   
Sbjct  419  KYVINSGREWFEIWVPQNPRFWKMPKLVFPDISVNPRFYFDKGGKIVNGNCYWIVAESAE  478

Query  484  SNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISL  543
              ++L LI G+ NS  M+KYHD+ F NKLY+GRRRY TQYV +YPIPDP+S  ++EI++L
Sbjct  479  KEELLLLIQGVANSNLMTKYHDLVFNNKLYSGRRRYFTQYVEQYPIPDPDSSEAREIVTL  538

Query  544  VRELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            V++L N  K+ + I  +E  +EK +  AF +E++
Sbjct  539  VKKL-NQTKDEESIQSLEIELEKQVASAFGVEAV  571


>WP_130059682.1 methyltransferase domain-containing protein [Bacteroides salyersiae]
 RYT44773.1 methyltransferase domain-containing protein [Bacteroides salyersiae]
Length=574

 Score = 509 bits (1310),  Expect = 6e-172, Method: Compositional matrix adjust.
 Identities = 265/567 (47%), Positives = 370/567 (65%), Gaps = 18/567 (3%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQLE  73
            K TGA FTP +LA  +A+RI        N   +VLDPACG+GELLLA+     + NI  +
Sbjct  15   KNTGATFTPKELAVFLAERIASNIS---NTHQKVLDPACGEGELLLAMGHTLLNSNISFD  71

Query  74   LIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDN-YDLFNIEEL---EPVDI  129
            + G D +   ++I   RL  +  K   L  +DFL+ +   +N  DLF ++        DI
Sbjct  72   IAGFDTNDKYLDITKNRLKSAFSKEMCLFCEDFLQAIDIHNNPIDLFQVKSCLLNNCYDI  131

Query  130  IIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRYL  189
            +IANPPYVRTQILG+E+AQ L +KF LKGRVDLY  FL+AMT+ LK  GI+GVITSNRYL
Sbjct  132  VIANPPYVRTQILGSEQAQMLAKKFQLKGRVDLYYPFLIAMTESLKEGGILGVITSNRYL  191

Query  190  TTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFFK  249
            +TK G   R++L +N++ILE++DLGD+K FEAAVLPAIF G+K  +      S    F K
Sbjct  192  STKSGECIRQYLSANYDILELIDLGDTKLFEAAVLPAIFIGKKTTRR----KSTSSTFIK  247

Query  250  IYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWILAT  309
            IYE  D   ++S  +  +S+I +L+  + G Y V DK Y  ++G +I     K  W + +
Sbjct  248  IYE--DFNENNSEATPTDSIINVLKNKEMGCYKVGDKFYKKTIGTLIYEVGSKSSWSMFS  305

Query  310  EDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPIIS  369
             +EY+W  K++  A   IEDF  VKVGIK+TAD VFI  +W +L E + PE++LL+ +IS
Sbjct  306  GEEYKWVSKIDSAAKNHIEDFFKVKVGIKSTADKVFISDNWDDLKEIK-PEEELLKDLIS  364

Query  370  ADQANKWSVSLVGNNK-KVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLK  428
             +  N W  +   N+K KVLY H   +G+   +++ ++P A+ YL  H+E L SRKY++ 
Sbjct  365  QENINAWHAT--NNSKLKVLYPHICVNGKKTTVDIHKYPNAEMYLLQHEEILRSRKYLID  422

Query  429  ANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDIL  488
            A R WYE+WVPH P +WDKPK++FPD S  P+F+++  G +V+GNCYWI  + E   ++L
Sbjct  423  AGRQWYELWVPHRPEVWDKPKLVFPDISSVPRFYFDTDGKIVNGNCYWIAARNEKETELL  482

Query  489  FLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRELV  548
             LI GI NSK M+KYHD+ F NKLY+G+RRY+TQYV KYP+PD  S  S EIIS+V+EL 
Sbjct  483  MLIQGIANSKLMTKYHDLVFNNKLYSGKRRYITQYVEKYPLPDINSPISTEIISIVKEL-  541

Query  549  NNKKETQDINEIENRIEKLILRAFDIE  575
            N      DI+++EN +E  + +AF ++
Sbjct  542  NKSSNVLDISKLENLLEICVAKAFGVD  568


>RIK81909.1 modification methylase [Planctomycetes bacterium]
Length=572

 Score = 504 bits (1297),  Expect = 6e-170, Method: Compositional matrix adjust.
 Identities = 251/564 (45%), Positives = 355/564 (63%), Gaps = 7/564 (1%)

Query  13   QKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQ-  71
            QK TGAHFTP  LA V+A+RI  + +  +    R+LDPACGDG LL+A+     +  ++ 
Sbjct  5    QKQTGAHFTPPDLAAVVAERIAPHVEAMRG-AARILDPACGDGNLLVAMASALSAARLRR  63

Query  72   LELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNIEELEPVDIII  131
              L GV+ D ++  +   R+         L+  DFL++V +   Y   +   L   D II
Sbjct  64   CTLSGVEEDAESFALLRRRIEALPALATDLVCGDFLDIVDDASLYS--SAPRLPLSDAII  121

Query  132  ANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRYLTT  191
            ANPPYVRTQ+LGA +AQ L  +F+L+GRVDLYQAFLVAMT+QL+  G++GVITSNR+LTT
Sbjct  122  ANPPYVRTQVLGAARAQALASRFDLRGRVDLYQAFLVAMTRQLRPGGVLGVITSNRFLTT  181

Query  192  KGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFFKIY  251
            +GG S R FL S + +LEI+DLGD+K FEAAVLPA+ F  K+  E     +    F +IY
Sbjct  182  RGGASIRHFLRSRYELLEIVDLGDTKLFEAAVLPALVFARKRCGERDSLRAERTAFVRIY  241

Query  252  EQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWILATED  311
            E  D    ++   + +S+ +L+   ++G + V D++Y ++ G +    +   PW L T  
Sbjct  242  ESVDGIRDNA--EQVSSVTDLVRRPRTGRFIVRDRSYDVAAGTLEMDSDDARPWTLLTSK  299

Query  312  EYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPIISAD  371
            E  W  +V   A   I D A ++VGIKTTADSVFIR DW ELP+   P    L+P++S D
Sbjct  300  ENSWVEQVRAKATCRIADVARIRVGIKTTADSVFIRDDWEELPQAVRPAAHHLKPVLSHD  359

Query  372  QANKWSVSLVGNNKK-VLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLKAN  430
             A +W   +  +  + VLYTHE+R+G+ +AI  +E      YL +++ERL SR YV+ A 
Sbjct  360  DAARWRRRVTSSAARMVLYTHEVRNGKRRAIRFDERSATWRYLLANRERLESRTYVVDAG  419

Query  431  RNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDILFL  490
            R+WYEIWVP DP  W  PKI+FPD SPEP+FF +  GSVVDGNCYWI  +     ++L L
Sbjct  420  RHWYEIWVPQDPQGWSVPKIVFPDISPEPRFFLDRGGSVVDGNCYWITTRDLADEELLLL  479

Query  491  IMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRELVNN  550
            I+G+ NS  ++++H++AF NKLY+ RRRYLTQYV +YP+P  +S  +K+I+  VR L   
Sbjct  480  ILGVANSSVIARFHELAFPNKLYSQRRRYLTQYVGEYPLPARDSREAKQIVKAVRVLTGA  539

Query  551  KKETQDINEIENRIEKLILRAFDI  574
                 +I  ++  I++L   AF +
Sbjct  540  AVSPAEIASLQLEIDELTAAAFGV  563


>ADX97298.1 M.ClaI [Caryophanon latum]
Length=582

 Score = 504 bits (1297),  Expect = 8e-170, Method: Compositional matrix adjust.
 Identities = 267/580 (46%), Positives = 387/580 (67%), Gaps = 27/580 (5%)

Query  13   QKATGAHFTPDKLAEVIAKRILDY---FKGEKNRVIRVLDPACGDGELLLAINKVAQSMN  69
            +K  G H+T  +L+  +A R+ +    F   KN  +++LDP+CGDGELL A  K+    N
Sbjct  7    KKEDGIHYTAKELSYFMASRLKEASKKFFTAKNSEVQLLDPSCGDGELLKAAAKIFSEDN  66

Query  70   IQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN---------  120
            I+L  IGVD D  AIN A +  ++    N  L   D+L + +  +  DLFN         
Sbjct  67   IKL--IGVDTDEYAINAAQQYFTQED--NVSLFINDYLNLFAREEEQDLFNLLPNEPDSF  122

Query  121  -IEE--LEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSN  177
             IE+  L+PVD+I+ANPPYVRTQ++GA+K+Q L +KFNLKG++DLY  FLVAMT+ LK N
Sbjct  123  FIEDGYLKPVDLILANPPYVRTQVMGADKSQILADKFNLKGKIDLYHVFLVAMTKHLKDN  182

Query  178  GIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEY  237
            GII VITSNRYLTT GG   R FL +N+ ILE++DLGD+K F+AAVLPAIF G KK+   
Sbjct  183  GIICVITSNRYLTTAGGKDIRSFLDANYEILEVIDLGDTKLFDAAVLPAIFIGRKKSPSE  242

Query  238  QKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIIS  297
              +N  V K ++IYE++  + + +V  +  S+ E+L    SG+Y    K Y +  G +  
Sbjct  243  NIKNDKV-KCYRIYEET--KKTETVIEKCESIYEILSKKTSGIYEANKKNYKVMSGILKV  299

Query  298  PENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFI--RSDWGELPE  355
            P++ KE W++A+ +E EW  ++ ++++    D   V+VGIKTTAD+VFI  +S+W +LP 
Sbjct  300  PQDPKELWVMASNEEKEWVEQIKKSSFCLFSDLFKVRVGIKTTADNVFINNQSEWEKLPS  359

Query  356  EQIPEDKLLRPIISADQANKWSVSLVG-NNKKVLYTHEIRDGQIKAINLEEFPRAKNYLE  414
            +  PE+++L  +IS+D   KW+ +    + KK+LYTH+  +G+ +AI+L E+   KNYLE
Sbjct  360  DIKPENEVLHSLISSDNIQKWTCNNSKISQKKILYTHQTINGKRQAIDLNEYEHTKNYLE  419

Query  415  SHKERLASRKYVLKA-NRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGN  473
             HKE+L++R Y+ K+  R+WYEIWVP +P+ + K KI+FPD SPEPKF  +    +VDGN
Sbjct  420  FHKEQLSARTYLTKSKTRHWYEIWVPQEPNDFKKTKIVFPDISPEPKFSIDTNQYLVDGN  479

Query  474  CYWIIPKKEN-SNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDP  532
            CYWI  K+ N S D+L+L   + NS  M+++H I FQN LYAGR+RYLTQYVN+Y  P+P
Sbjct  480  CYWITLKESNQSTDLLYLAAAVANSDLMTRFHSIEFQNVLYAGRKRYLTQYVNEYVFPNP  539

Query  533  ESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAF  572
            +SIY+KEII+L ++LV+ K   ++I  IE ++  L+ + F
Sbjct  540  DSIYAKEIINLSKKLVSEKLLNEEIISIEKKLNILVEKCF  579


>WP_026473107.1 hypothetical protein [Alkaliflexus imshenetskii]
Length=569

 Score = 501 bits (1290),  Expect = 7e-169, Method: Compositional matrix adjust.
 Identities = 262/569 (46%), Positives = 374/569 (66%), Gaps = 17/569 (3%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQLE  73
            K TGA FTP +LA+ +A+++  Y  G+    ++VLDPACGDG LL+A+ +V Q  N   E
Sbjct  9    KQTGATFTPKELAQFLAQKLYYYQSGDN---LKVLDPACGDGALLMAMAEVMQKNNRSFE  65

Query  74   LIGVDFDIDAINIANERLSRSGH-KNFRLINKDFLEMVS-EGDNYDLFNIEEL---EPVD  128
            L G D + + ++I  E L  + H KN  L   +FLE+V  +     LF+ +     E  D
Sbjct  66   LHGYDSNNEYLSIGKENLLINNHIKNANLTLANFLEVVDLKKKQLSLFDNDSSSVNEFAD  125

Query  129  IIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRY  188
            +IIANPPYVRTQILGA+++Q L +KF LKGRVDLY  FL+AMT  LK NG+IGVITSNRY
Sbjct  126  LIIANPPYVRTQILGADQSQLLSKKFGLKGRVDLYYPFLIAMTHALKENGLIGVITSNRY  185

Query  189  LTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFF  248
            L+TK G S RKFL  N+ +LE++DLGD+K F+AAVLPAIF G KK+       +   KF+
Sbjct  186  LSTKSGESVRKFLTDNYEVLEVIDLGDTKLFDAAVLPAIFIGRKKSNV----TNTTSKFY  241

Query  249  KIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWILA  308
            KIYE+ +      +    NS+ ++L     G +SV +K    S G +   +  +  W + 
Sbjct  242  KIYEELNGYEGELIPE--NSVFDVLNSENDGFFSVGEKRLKKSSGILKFSKTKENTWTML  299

Query  309  TEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPII  368
            ++ E  W  ++  N+  FI+D   V+VGIKTTAD VFI   W +L   + PED+LL+ +I
Sbjct  300  SKKEGLWVSEIESNSKTFIKDHFKVRVGIKTTADKVFISDKWADLNGTK-PEDELLKELI  358

Query  369  SADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLK  428
            S +    W  +      KVLY H  +DG+   INLE++P+AK YL SH+E+L SRKY++ 
Sbjct  359  SQENIKPWG-ACDKKKLKVLYPHYSKDGKKYTINLEKYPKAKAYLLSHEEKLKSRKYLID  417

Query  429  ANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDIL  488
            A RNW+EIWVP +PS W+ PKI+FPD S  P+F+Y++ G +V+GNCYWI+ +KE  N+IL
Sbjct  418  AGRNWFEIWVPQNPSFWNLPKIVFPDISTGPRFYYDNTGKIVNGNCYWIVAEKEADNNIL  477

Query  489  FLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRELV  548
             LI GI NSK M+KYHD+ F NKLY+GRRRY +QYV  YP+PD ++I S+E+I+ V++ +
Sbjct  478  LLIQGIANSKLMTKYHDLVFNNKLYSGRRRYFSQYVENYPLPDIDTIESREVINTVKQ-I  536

Query  549  NNKKETQDINEIENRIEKLILRAFDIESL  577
            N   E + I+++   +E  + +A+++ ++
Sbjct  537  NGTNEEKIISKLTKVLENQVAKAYNVSTV  565


>WP_091102821.1 hypothetical protein [Flavobacterium marinum]
 SEI03401.1 TaqI-like C-terminal specificity domain-containing protein [Flavobacterium 
marinum]
Length=590

 Score = 492 bits (1267),  Expect = 4e-165, Method: Compositional matrix adjust.
 Identities = 267/571 (47%), Positives = 377/571 (66%), Gaps = 23/571 (4%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQLE  73
            K TGA FTP +LA  +A+RI  Y K   NRV   LDPACG+GELL+A+ +V     I   
Sbjct  28   KNTGATFTPKELAVFLAERIALYAKSTSNRV---LDPACGEGELLVAMGEVLNEKAIDFS  84

Query  74   LIGVDFDIDAINIANERLSRSGHKNFRLINKDFL---EMVSEGDNYDLFNIEELEPV---  127
            L G D +   ++ + +RL   G K   LI++DFL   ++ S  +   LF+ E    V   
Sbjct  85   LTGYDANEQYLSFSKDRLLCFGKKKSDLIHEDFLLSVDLSSTRNTPSLFD-ECTSSVNNS  143

Query  128  -DIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSN  186
             DI+IANPPYVRTQILG E+AQ L  KFNLKGRVDLY  FL+AMT+ LK NGI+GVITSN
Sbjct  144  FDIVIANPPYVRTQILGTEQAQNLARKFNLKGRVDLYYPFLMAMTESLKENGILGVITSN  203

Query  187  RYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPK  246
            RYL+TK G S RKFL  N+ ILE++DLGD+K F+AAVLPAIF G KK    ++++ +   
Sbjct  204  RYLSTKSGESIRKFLSENYEILELIDLGDTKLFDAAVLPAIFIGRKK----KQKSPSSAS  259

Query  247  FFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPENYKEPW  305
            F KIYE+ +      ++ E  ++ ++L+ N+SG +  E+ K Y  S G +         W
Sbjct  260  FIKIYEELNGYKGDLISVE--TVFDILKNNQSGYFVTENGKRYKKSSGALKYKVGSTSCW  317

Query  306  ILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLR  365
             + + DE +W  K+++ +   +EDF  VKVGIK+TAD VFI   W EL   + PE++LL+
Sbjct  318  EMLSGDESDWVSKIDKASKNRVEDFFKVKVGIKSTADKVFISDKWEELNGTK-PENELLK  376

Query  366  PIISADQANKWSVSLVGNNK-KVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRK  424
             +IS +    W+     N K KVLY H   +G+ + +++E++P+AK Y   H++RL SRK
Sbjct  377  DLISQENIEPWNAK--ENFKLKVLYPHISVNGEKQTVDIEKYPKAKKYFTQHEDRLKSRK  434

Query  425  YVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENS  484
            Y++ A R W+E+WVPH P  W  PK++FPD S +P+F++++ G +V+GNCYWI+  K+  
Sbjct  435  YLIDAGRQWFELWVPHRPDQWRFPKLVFPDISLKPRFYFDNGGKIVNGNCYWIVATKDED  494

Query  485  NDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLV  544
             + L LI GI NSK M+KYHD+ F NKLY+GRRRY TQYV KYP+PD +S  SKEII++V
Sbjct  495  VEKLMLIQGIANSKLMTKYHDLVFNNKLYSGRRRYFTQYVEKYPLPDFKSEKSKEIITIV  554

Query  545  RELVNNKKETQDINEIENRIEKLILRAFDIE  575
            ++L + K ET+ I+++EN++E L+  +F +E
Sbjct  555  KKLNHTKDETK-ISKLENQLEILVAESFGVE  584


>WP_069512061.1 modification methylase [Lysinibacillus sphaericus]
 OEC02065.1 modification methylase [Lysinibacillus sphaericus]
Length=578

 Score = 488 bits (1256),  Expect = 1e-163, Method: Compositional matrix adjust.
 Identities = 263/587 (45%), Positives = 382/587 (65%), Gaps = 32/587 (5%)

Query  9    TVSRQKATGAHFTPDKLAEVIAKRILDYF-KGEKNRV--IRVLDPACGDGELLLAINKVA  65
            ++S  K TG+H+T + L+  +A R+   F K   N +  + ++DP+CGDGELL A   + 
Sbjct  3    SLSEAKETGSHYTSNDLSHFMADRLKQAFLKYNFNEIENLTLIDPSCGDGELLKAAATLF  62

Query  66   QSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNY--DLFNIE-  122
            +  +++L  +GVD D +AI  A+         +  +   D+LE+    DNY  DLF++  
Sbjct  63   EDNSVKL--LGVDTDANAIQSASNYFGEDS--SVSVFQSDYLELF---DNYKTDLFSLNG  115

Query  123  ----------ELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQ  172
                       L  VD+I+ANPPYVRTQ++GA++AQKL E F LKGRVDLYQAFLVAMTQ
Sbjct  116  DKSNDLISEGTLNLVDLILANPPYVRTQVMGADRAQKLGEMFGLKGRVDLYQAFLVAMTQ  175

Query  173  QLKSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEK  232
             LK+NG+I VITSNRYLTT GG   R +L  N+ ILE++DLGD+K F AAVLPAIF G K
Sbjct  176  HLKANGLICVITSNRYLTTAGGKDIRAYLDKNYEILEVIDLGDTKLFNAAVLPAIFIGRK  235

Query  233  KNKEYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISL  292
            K +    +N NV K ++IYE +   +   V+    S+ E+L  N+SG+Y+V +K YS+  
Sbjct  236  KAENENIKNENV-KCYRIYEDT---SDGEVDEVCTSIYEILYKNESGIYAVGNKKYSVMS  291

Query  293  GKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIR--SDW  350
            G +  PE+ KE W++A++++ EW  ++  N++    D   V+VGIKTTAD+VFI   ++W
Sbjct  292  GYLKVPEDSKELWVMASKEDKEWVNQIKNNSFCKFSDMFKVRVGIKTTADNVFIHNNNEW  351

Query  351  GELPEEQIPEDKLLRPIISADQANKW-SVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRA  409
              L E   PE +LL P+IS+D   KW S   +   KK+LYTH+  +G+ KAI+L+++  A
Sbjct  352  EALAENIKPEAELLNPLISSDNIQKWKSDGQLVEQKKILYTHQFVEGKRKAIDLDDYVNA  411

Query  410  KNYLESHKERLASRKYVLKA-NRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGS  468
            K YL  H E+LA R Y+ K+  R+WYEIWVP +P  +   KI+FPD S EPKF  +    
Sbjct  412  KAYLLHHHEQLAGRTYLAKSKTRHWYEIWVPQEPMAFKDLKIVFPDISLEPKFSIDTNEY  471

Query  469  VVDGNCYWIIPKKENSN-DILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKY  527
            +VDGNCYWI  K+++++ D+L+L   I NS+ M+++H I FQN LY+GR+RYLTQYV+ Y
Sbjct  472  LVDGNCYWITLKEQDADRDLLYLAAAIANSQLMNRFHGIEFQNVLYSGRKRYLTQYVDNY  531

Query  528  PIPDPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
             +PDP SIYS++I+ + + +V    E ++I ++E  IE+ +  AF +
Sbjct  532  VLPDPSSIYSRKIVEVTKNIVTQNLEIEEIKQLELEIEEQVRLAFSV  578


>WP_093363758.1 hypothetical protein [Sphingobacterium wenxiniae]
 SFS49035.1 TaqI-like C-terminal specificity domain-containing protein [Sphingobacterium 
wenxiniae]
Length=590

 Score = 488 bits (1256),  Expect = 2e-163, Method: Compositional matrix adjust.
 Identities = 267/571 (47%), Positives = 379/571 (66%), Gaps = 23/571 (4%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQLE  73
            K TGA FTP +LA  +A+RI  Y K   NRV   LDPACG+GELL+A+ +V     I   
Sbjct  28   KNTGATFTPKELAVFLAERIALYAKSTSNRV---LDPACGEGELLVAMGEVLNEKAIDFS  84

Query  74   LIGVDFDIDAINIANERLSRSGHKNFRLINKDFL---EMVSEGDNYDLFNIEELEPV---  127
            L G D +   ++ + +RL   G K   LI++DFL   ++ S  +   LF+ E    V   
Sbjct  85   LTGYDANEQYLSFSKDRLLCFGKKKSDLIHEDFLLSVDLSSTRNTPSLFD-ECTSSVNNS  143

Query  128  -DIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSN  186
             DI+IANPPYVRTQILG E+AQ L  KFNLKGRVDLY  FL+AMT+ LK NGI+GVITSN
Sbjct  144  FDIVIANPPYVRTQILGTEQAQNLARKFNLKGRVDLYYPFLMAMTESLKENGILGVITSN  203

Query  187  RYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPK  246
            RYL+TK G S RKFL  N+ ILE++DLGD+K F+AAVLPAIF G    ++ ++++S+   
Sbjct  204  RYLSTKSGESIRKFLSENYEILELIDLGDTKLFDAAVLPAIFVG----RKKKQKSSSSAS  259

Query  247  FFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPENYKEPW  305
            F KIYE+ +      ++ E  ++ ++L+ N+SG +  E+ K Y  S G +         W
Sbjct  260  FIKIYEELNGYKGDLISVE--TVFDILKNNQSGYFVTENGKRYKKSSGALKYKVGSTSCW  317

Query  306  ILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLR  365
             + + DE +W  K+++ +   +EDF  VKVGIK+TAD VFI   W EL   + PED+LL+
Sbjct  318  EMLSGDESDWVSKIDKASKNRVEDFFKVKVGIKSTADKVFISDKWEELNGTK-PEDELLK  376

Query  366  PIISADQANKWSVSLVGNNK-KVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRK  424
             +IS +    W+ +   N K KVLY H   +G+ + +++E++P+AK Y   H++RL SRK
Sbjct  377  DLISQENIEPWNAT--ENFKLKVLYPHISVNGEKQTVDIEKYPKAKKYFTQHEDRLKSRK  434

Query  425  YVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENS  484
            Y++ A R W+E+WVPH P  W  PK++FPD S +P+F++++ G +V+GNCYWI+  K+  
Sbjct  435  YLIDAGRQWFELWVPHRPDQWRFPKLVFPDISLKPRFYFDNGGKIVNGNCYWIVATKDED  494

Query  485  NDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLV  544
             + L LI GI NSK M+KYHD+ F NKLY+GRRRY TQYV KYP+PD +S  SKEII++V
Sbjct  495  VEKLMLIQGIANSKLMTKYHDLVFNNKLYSGRRRYFTQYVEKYPLPDFKSEKSKEIITIV  554

Query  545  RELVNNKKETQDINEIENRIEKLILRAFDIE  575
            ++L + K ET+ I+++EN++E L+  +F +E
Sbjct  555  KKLNHTKDETK-ISKLENQLEILVAESFGVE  584


>WP_094415660.1 methyltransferase domain-containing protein [Flavobacterium cyanobacteriorum]
 OYQ34751.1 hypothetical protein CHU92_11380 [Flavobacterium cyanobacteriorum]
Length=570

 Score = 482 bits (1241),  Expect = 1e-161, Method: Compositional matrix adjust.
 Identities = 261/577 (45%), Positives = 366/577 (63%), Gaps = 21/577 (4%)

Query  9    TVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSM  68
            T  + K TGA FTP +L+  +A+RI  Y K    +V   LDPACG+GELL+A+  +    
Sbjct  3    TKEQIKNTGATFTPKELSVFLAERITSYVKPNYQKV---LDPACGEGELLIAMGNILSDS  59

Query  69   NIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMV---SEGDNYDLFNIEELE  125
             I   L G D +   ++ A ER  R G +N +LI++DFL+ +   S   N  LF      
Sbjct  60   AIDFSLTGYDANEQYLSFAQERTLRFGAENIKLIHEDFLQAIDVSSNQSNLGLFQEYNKS  119

Query  126  PV----DIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIG  181
             V    DI+IANPPYVRTQILG E+AQ+L +KFNLKGRVDLY  FL+AMT+ LK  GI+G
Sbjct  120  FVNNSFDIVIANPPYVRTQILGTEQAQELAQKFNLKGRVDLYYPFLIAMTESLKEGGILG  179

Query  182  VITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKEN  241
            VITSNRYL+TKGG S RKFL  N+ ILE++DLGD+K F+AAVLPAIF G KK    + ++
Sbjct  180  VITSNRYLSTKGGESIRKFLSENYEILELIDLGDTKLFDAAVLPAIFIGRKK----KLKS  235

Query  242  SNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENY  301
             +   F KIYE+ +      +  E  S+ E+L   +SG +    K Y  S G +      
Sbjct  236  PSSANFIKIYEELNGYKGDLIPVE--SVYEVLNNEQSGYFVANGKRYKKSSGVLKYKIAS  293

Query  302  KEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPED  361
               W + + +E +W  K+++ +   + D   VKVGIK+TAD VFI   W  L   + PED
Sbjct  294  GACWEMLSNNESDWVSKIDKASKNRVGDLFKVKVGIKSTADKVFISDKWENLNGTK-PED  352

Query  362  KLLRPIISADQANKWSVSLVGNNK-KVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420
            +LL+ +IS +    W+ +   N K KVLY H    G+ + +++E++P+AK Y   H+E+L
Sbjct  353  ELLKELISQENIEPWNAT--DNFKLKVLYPHISVGGEKQTVDIEKYPKAKKYFLQHEEKL  410

Query  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480
             SRKY+++A R W+E+WVPH P  W  PK++FPD S +P+F+++  G +V+GNCYWI+  
Sbjct  411  KSRKYLIEAGRQWFELWVPHRPDQWKYPKLVFPDISFKPRFYFDKGGKIVNGNCYWIVAA  470

Query  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540
            KE   + L LI GI NSK M+KYHD+ F NKLY+GRRRY TQYV +YP+PD  S  +KEI
Sbjct  471  KEEDVEKLLLIQGIANSKLMTKYHDLVFNNKLYSGRRRYFTQYVERYPLPDFNSSKAKEI  530

Query  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            IS+V++L N   +  +I+E+EN +E  +  +F +E +
Sbjct  531  ISIVKKL-NQSNDKTEISELENLLEIKVAESFGVEPI  566


>WP_034298709.1 methyltransferase domain-containing protein [Alkalibacterium 
sp. AK22]
 EXJ24411.1 DNA modification methyltransferase [Alkalibacterium sp. AK22]
Length=564

 Score = 479 bits (1233),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 265/577 (46%), Positives = 372/577 (64%), Gaps = 36/577 (6%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEK-----NRVIRVLDPACGDGELLLAINKVAQSM  68
            K TG+H+T ++L+  +AK +  ++  +      + ++ +LDP+CG+G LL A+ K  +  
Sbjct  7    KQTGSHYTSNELSIFMAKLLKKHYTKDNTYTNNSDMLNLLDPSCGEGHLLKAVEK--EFS  64

Query  69   NIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNIEE-----  123
             I  +LIGVD + +A  +A   L++   +N  +   D+LE + E +  DLFN  E     
Sbjct  65   EIPHKLIGVDINEEAAEVARNNLNK---ENTTITTCDYLEQIPEKE-IDLFNSYENNHKV  120

Query  124  -LEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGV  182
              + VD+IIANPPYVRTQ+L    ++ L + + LKG+VDLYQ F+ AMT  LK NGII V
Sbjct  121  IPDKVDLIIANPPYVRTQLLNKSTSETLVKNYGLKGKVDLYQIFIAAMTNNLKENGIICV  180

Query  183  ITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENS  242
            ITSNRYLTT+ G +TRK L  N+ ILE++DLGD+K FEAAVLPAIF G+KK++    +N 
Sbjct  181  ITSNRYLTTESGKTTRKMLSENYEILEVLDLGDTKLFEAAVLPAIFIGKKKSQ--PNKNI  238

Query  243  NVPKFFKIYEQSD----IEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISP  298
            N   F KIYE +D    I+ S+S+   FN L      ++SG Y V  K Y +  G +  P
Sbjct  239  NAIPFTKIYETTDKHDEIKESASI---FNLL-----QSESGKYFVGAKKYELLKGYLKIP  290

Query  299  ENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQI  358
            E+  + WI+A+ +  EW   +  N+     D   V+VGIKTTAD VFIR++W +LP    
Sbjct  291  EDPSDLWIMASPENIEWAKTLRSNSNKKFSDIFKVRVGIKTTADKVFIRNNWSDLPSNIT  350

Query  359  PEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKE  418
            PE ++L  +IS+    KWS+   G   K+LYTHE+ +G+ K I+ E++PRAK YL+ +KE
Sbjct  351  PEPEVLHNLISSRNIGKWSLDH-GYTSKILYTHEVVEGKRKVIDFEKYPRAKKYLDENKE  409

Query  419  RLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWII  478
             L+SRKYV+KANR WYEIWVP DP    + K++FPD S  PKF  ++ GS+VDGNCYW+ 
Sbjct  410  ILSSRKYVIKANRKWYEIWVPQDPEAMKRKKVVFPDISQSPKFMVDEDGSMVDGNCYWLT  469

Query  479  PKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSK  538
             K  NS D L+L   + NS+ MSKYH I FQN LY+GR+RY+TQYVNKY +PD E+  +K
Sbjct  470  LKDGNSEDYLYLAAAVANSRIMSKYHSIEFQNVLYSGRKRYITQYVNKYLLPDIETEEAK  529

Query  539  EIISLVRELVN-NKKETQDINEIENRIEKLILRAFDI  574
            E+ISL ++L+  N  ET+    IE +IE+L+   F I
Sbjct  530  EVISLAKQLITENDTETE---VIEEKIEQLLNICFKI  563


>WP_103913699.1 methyltransferase domain-containing protein [Chryseobacterium 
humi]
 SEG21038.1 TaqI-like C-terminal specificity domain-containing protein [Chryseobacterium 
humi]
Length=579

 Score = 478 bits (1231),  Expect = 5e-160, Method: Compositional matrix adjust.
 Identities = 256/570 (45%), Positives = 363/570 (64%), Gaps = 20/570 (4%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQLE  73
            K TGA FTP +L+  +A+RI  Y     +RV   LDPACG+ ELL+A+ +V         
Sbjct  16   KNTGATFTPRELSVFLAERIGYYVNSNHSRV---LDPACGEAELLVAMGEVLSERGCDFS  72

Query  74   LIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMV--SEGDN----YDLFNIEELE-P  126
            L G D + + +N A  RLS   +K   LI  DFL  V  S  +N    +D  +  E+   
Sbjct  73   LTGFDSNKEYLNFAKTRLSSLSNKKTDLILGDFLMSVDVSNSNNPPSLFDALSTSEVNNS  132

Query  127  VDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSN  186
             D++IANPPYVRTQILG E+AQ L  KFNLKGRVDLY  FL++MT+ LK  GI+GVITSN
Sbjct  133  FDVVIANPPYVRTQILGTEQAQNLARKFNLKGRVDLYYPFLISMTESLKEGGILGVITSN  192

Query  187  RYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPK  246
            RYL+TKGG S RK+L  N+ ILE++DLGD+K F+AAVLPAIF G KK    +++  +   
Sbjct  193  RYLSTKGGESIRKYLSENYEILELIDLGDTKLFDAAVLPAIFIGRKK----KQKKPSAAN  248

Query  247  FFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPENYKEPW  305
            F K+YE+  +   +   +   S+ ++L+   SG +  E+ K Y  S G +         W
Sbjct  249  FIKVYEE--LNGYNGELTPIESVYDVLKSKHSGYFVTENGKRYKKSSGNLKYKIGSGSCW  306

Query  306  ILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLR  365
             + +  E EW  K+++ A   +EDF  VKVGIK+TAD VFI   W +L   + PED LL+
Sbjct  307  EMLSSGESEWVYKIDKAAKNRVEDFFKVKVGIKSTADKVFISDKWEDLNGTK-PEDDLLK  365

Query  366  PIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKY  425
             +IS +    W+ +      KVLY H   +G+ + I++E++P+AK Y   H+E+L +RKY
Sbjct  366  ELISQENIEPWTAT-DNFELKVLYPHISVNGEKQTIDIEKYPKAKKYFVQHEEKLRARKY  424

Query  426  VLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSN  485
            ++ A R W+E+WVPH P  W  PK++FPD S +P+F+ +  G +V+GNCYWI+  KE   
Sbjct  425  LIDAGRQWFELWVPHRPDQWKYPKLVFPDISLKPRFYLDTNGRIVNGNCYWIVANKEEDV  484

Query  486  DILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVR  545
            D L LI GI NSK M+KYHD+ F NKLY+GRRRY +QYV KYP+PD +S+ +KEII++V+
Sbjct  485  DKLLLIQGIANSKLMTKYHDLVFNNKLYSGRRRYFSQYVEKYPLPDFDSLKAKEIIAIVK  544

Query  546  ELVNNKKETQDINEIENRIEKLILRAFDIE  575
            +L N   +T +I+++EN++E  +  +F +E
Sbjct  545  DL-NQSNDTLEISKLENQLEIKVAESFRVE  573


>WP_127822314.1 methyltransferase domain-containing protein [Flavobacterium columnare]
 RVU87071.1 methyltransferase domain-containing protein [Flavobacterium columnare]
Length=570

 Score = 478 bits (1230),  Expect = 8e-160, Method: Compositional matrix adjust.
 Identities = 261/577 (45%), Positives = 369/577 (64%), Gaps = 21/577 (4%)

Query  9    TVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSM  68
            T  + K TGA FTP +LA  +A+RI  Y + + NRV   LDPACG+GELL+A+ +V    
Sbjct  3    TKEQIKNTGATFTPKELAVFLAERIASYAQPKNNRV---LDPACGEGELLIAMGEVLNEK  59

Query  69   NIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFL---EMVSEGDNYDLFNIEELE  125
                 L G D +   ++ A +RL   G     L+++DFL   +M S  +   LF+ E   
Sbjct  60   AFDFSLTGYDANEQYLSFAKDRLFSFGKDKSDLVHEDFLLSVDMSSAQNTPSLFD-ECTS  118

Query  126  PV----DIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIG  181
             V    DI+IANPPYVRTQILG EKAQ L  KFNLKGRVDLY  FL+AMT+ LK  G++G
Sbjct  119  SVNNSFDIVIANPPYVRTQILGTEKAQNLARKFNLKGRVDLYYPFLIAMTESLKEGGLLG  178

Query  182  VITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKEN  241
            VITSNRYL+TK G S RK+L  N+ ILE++DLGD+K FEAAVLPAIF G+KK ++     
Sbjct  179  VITSNRYLSTKSGESVRKYLSENYEILELIDLGDTKLFEAAVLPAIFIGKKKKQKSASSA  238

Query  242  SNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLY-SVEDKTYSISLGKIISPEN  300
            +    F KIYE+ +      ++ E  S+ ++L+ N SG + +   K Y  S G +     
Sbjct  239  N----FIKIYEELNGYKGDLISVE--SVYDVLKNNHSGYFVTTNGKRYKKSSGALKYKIG  292

Query  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360
                W + + +E  W  K+++     +EDF  VKVGIK+TAD VFI   W EL   + PE
Sbjct  293  STTCWEMLSNNESGWIAKIDKATKNRVEDFFKVKVGIKSTADKVFISDKWEELNGTK-PE  351

Query  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420
            D+LL+ +IS +    W+ +      KVLY H   +G+ + +N+E++P+AK Y   H+E+L
Sbjct  352  DELLKELISQENIEPWNAT-DNFELKVLYPHISVNGEKQTVNIEKYPKAKKYFTQHEEKL  410

Query  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480
              RKY++ A R W+E+WVPH P  W  PK++FPD S +P+F++++ G +V+GNCYWI+  
Sbjct  411  KGRKYLIDAGRQWFELWVPHRPDQWKYPKLVFPDISLKPRFYFDNGGKIVNGNCYWIVAT  470

Query  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540
            KE+  + LFLI G+ NSK M+KYHD+ F NKLY+GRRRY TQYV KYP+PD  S  +KEI
Sbjct  471  KESDVEKLFLIQGVANSKLMTKYHDLVFNNKLYSGRRRYFTQYVEKYPLPDFNSEIAKEI  530

Query  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            I +V+EL N+  +   I+++EN++E  + ++F +E +
Sbjct  531  IVIVKEL-NHSNDKTVISDLENQLEIAVAKSFGVEPV  566


>WP_108778098.1 methyltransferase domain-containing protein [Flavobacterium album]
 AWH85396.1 modification methylase [Flavobacterium album]
Length=571

 Score = 477 bits (1227),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 255/569 (45%), Positives = 370/569 (65%), Gaps = 21/569 (4%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQLE  73
            K TGA FTP +L+  +A+RI  Y     +   +VLDPACG+GELL+++  +  +  I   
Sbjct  9    KNTGATFTPKELSAFLAERIFYYIN---HSYQKVLDPACGEGELLISMGDLLSNSAIDFS  65

Query  74   LIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVS---EGDNYDLFNIEELEPV---  127
            L G D +   +  A ER+ R G +    +++DFL+ V      +N DLF       +   
Sbjct  66   LTGYDANQQYLRFAQERMLRFGSEKINFVHEDFLQAVDVSFRQNNLDLFEEYNKSSINNS  125

Query  128  -DIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSN  186
             DI+IANPPYVRTQILGAE+AQK+ + FNLKGR+DLY  FL++MT+ LK  GIIGVITSN
Sbjct  126  FDIVIANPPYVRTQILGAEQAQKIAKNFNLKGRIDLYYPFLISMTESLKEGGIIGVITSN  185

Query  187  RYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPK  246
            RYL+TKGG S RKFL  N+ ILE++DLGD+K F AAVLPAIF G+K+    +++ S+V  
Sbjct  186  RYLSTKGGESIRKFLSENYEILEVIDLGDTKLFNAAVLPAIFIGKKQ----KQKKSSVAN  241

Query  247  FFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWI  306
            F KIYE+ +      +  E  S+ E+L   +SG ++   K Y  S G +       E W 
Sbjct  242  FIKIYEELNGYKGDLIPLE--SVYEILSNKQSGYFTANGKRYKKSSGILKYEIASGECWE  299

Query  307  LATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRP  366
            L +  E +W  K+++ A   +E++  VKVGIK+TAD VFI   W EL + + PED+LL+ 
Sbjct  300  LLSGKESDWVSKIDKAAKNRVENYFKVKVGIKSTADKVFISDKWEELNDHK-PEDELLKD  358

Query  367  IISADQANKWSVSLVGNNK-KVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKY  425
            +IS +    W+   + N K KVLY H   +GQ + I++E++P+AK +   H+E+L +RKY
Sbjct  359  LISQENIEPWNA--IDNFKLKVLYPHISINGQKQTIDIEKYPKAKKFFLQHEEKLKARKY  416

Query  426  VLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSN  485
            ++++ R W+E+WV H P  W  PK++FPD S +P+F+++++G +V+GNCYWI+ +KE   
Sbjct  417  LIESGRQWFELWVSHRPDQWKYPKLVFPDISLKPRFYFDEEGKIVNGNCYWIVAEKEEDV  476

Query  486  DILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVR  545
            + L LI GI NSK M+KYHD+ F NKLY+GRRRY TQYV KYP+PD  S   KEIIS+V+
Sbjct  477  EKLLLIQGIANSKLMTKYHDLVFNNKLYSGRRRYFTQYVEKYPLPDISSYEGKEIISIVK  536

Query  546  ELVNNKKETQDINEIENRIEKLILRAFDI  574
             L+N   +  +++ +EN +E  + ++F +
Sbjct  537  -LLNQSNDEVEVSRLENELEIKVAKSFGV  564


>OXA83254.1 hypothetical protein B0A56_02000 [Flavobacterium columnare NBRC 
100251 = ATCC 23463]
Length=570

 Score = 475 bits (1222),  Expect = 1e-158, Method: Compositional matrix adjust.
 Identities = 260/577 (45%), Positives = 369/577 (64%), Gaps = 21/577 (4%)

Query  9    TVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSM  68
            T  + K TGA FTP +LA  +A+RI  Y + + NRV   LDPACG+GELL+A+ +V    
Sbjct  3    TKEQIKNTGATFTPKELAVFLAERIASYAQPKNNRV---LDPACGEGELLIAMGEVLNEK  59

Query  69   NIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFL---EMVSEGDNYDLFNIEELE  125
                 L G D +   ++ A +RL   G     L+++DFL   ++ S  +   LF+ E   
Sbjct  60   AFDFSLTGYDANEQYLSFAKDRLFCFGKDKSDLVHEDFLLSVDVSSAQNTPSLFD-ECTS  118

Query  126  PV----DIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIG  181
             V    DI+IANPPYVRTQILG EKAQ L  KFNLKGRVDLY  FL+AMT+ LK  G++G
Sbjct  119  SVNNSFDIVIANPPYVRTQILGTEKAQNLARKFNLKGRVDLYYPFLIAMTESLKEGGLLG  178

Query  182  VITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKEN  241
            VITSNRYL+TK G S RK+L  N+ ILE++DLGD+K FEAAVLPAIF G+KK ++     
Sbjct  179  VITSNRYLSTKSGESVRKYLSENYEILELIDLGDTKLFEAAVLPAIFIGKKKKQKSASSA  238

Query  242  SNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLY-SVEDKTYSISLGKIISPEN  300
            +    F KIYE+ +      ++ E  S+ ++L+ N SG + +   K Y  S G +     
Sbjct  239  N----FIKIYEELNGYKGDLISVE--SVYDVLKNNHSGYFVTANGKRYKKSSGALKYKIG  292

Query  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360
                W + + +E  W  K+++     +EDF  VKVGIK+TAD VFI   W EL   + PE
Sbjct  293  STTCWEMLSNNESGWIAKIDKATKNRVEDFFKVKVGIKSTADKVFISDKWEELNGTK-PE  351

Query  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420
            D+LL+ +IS +    W+ +      KVLY H   +G+ + +N+E++P+AK Y   H+E+L
Sbjct  352  DELLKELISQENIEPWNAT-DNFELKVLYPHISVNGEKQTVNIEKYPKAKKYFTQHEEKL  410

Query  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480
              RKY++ A R W+E+WVPH P  W  PK++FPD S +P+F++++ G +V+GNCYWI+  
Sbjct  411  KGRKYLIDAGRQWFELWVPHRPDQWKYPKLVFPDISLKPRFYFDNGGKIVNGNCYWIVAT  470

Query  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540
            KE+  + LFLI G+ NSK M+KYHD+ F NKLY+GRRRY TQYV KYP+PD  S  +KEI
Sbjct  471  KESDVEKLFLIQGVANSKLMTKYHDLVFNNKLYSGRRRYFTQYVEKYPLPDFNSEIAKEI  530

Query  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            I +V+EL N+  +   I+++EN++E  + ++F +E +
Sbjct  531  IVIVKEL-NHSNDKTVISDLENQLEIAVAKSFGVEPV  566


>WP_123910345.1 methyltransferase domain-containing protein [Flavobacterium columnare]
Length=573

 Score = 474 bits (1220),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 259/580 (45%), Positives = 370/580 (64%), Gaps = 21/580 (4%)

Query  4    VQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINK  63
            + K  T  + K TGA FTP +LA  +A+RI  Y + + NR+   LDPACG+GELL+A+ +
Sbjct  1    MSKMITKEQIKNTGATFTPKELAVFLAERIASYAQPKNNRI---LDPACGEGELLIAMGE  57

Query  64   VAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFL---EMVSEGDNYDLFN  120
            V         L G D +   ++ A +RL   G     L+++DFL   ++ S  +   LF+
Sbjct  58   VLNEKAFDFSLTGYDANEQYLSFAKDRLFSFGKDKSDLVHEDFLLSVDVSSAQNTPSLFD  117

Query  121  IEELEPV----DIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKS  176
             E    V    DI+IANPPYVRTQILG EKAQ L  KFNLKGRVDLY  FL+AMT+ LK 
Sbjct  118  -ECTSSVNNSFDIVIANPPYVRTQILGTEKAQNLARKFNLKGRVDLYYPFLIAMTESLKE  176

Query  177  NGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKE  236
             G++GVITSNRYL+TK G S RK+L  N+ ILE++DLGD+K FEAAVLPAIF G+KK ++
Sbjct  177  GGLLGVITSNRYLSTKSGESVRKYLSENYEILELIDLGDTKLFEAAVLPAIFIGKKKKQK  236

Query  237  YQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLY-SVEDKTYSISLGKI  295
                 +    F KIYE+ +      ++ E  S+ ++L+ N SG + +   K Y  S G +
Sbjct  237  SASSAN----FIKIYEELNGYKGDLISVE--SVYDVLKNNHSGYFVTTNGKRYKKSSGAL  290

Query  296  ISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPE  355
                     W + + +E  W  K+++     +EDF  VKVGIK+TAD VFI   W EL  
Sbjct  291  KYKIGSTTCWEMLSNNESGWIAKIDKATKNRVEDFFKVKVGIKSTADKVFISDKWEELNG  350

Query  356  EQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLES  415
             + PED+LL+ +IS +    W+ +      KVLY H   +G+ + +N+E++P+AK Y   
Sbjct  351  TK-PEDELLKELISQENIEPWNAT-DNFELKVLYPHISVNGEKQTVNIEKYPKAKKYFTQ  408

Query  416  HKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCY  475
            H+E+L  RKY++ A R W+E+WVPH P  W  PK++FPD S +P+F++++ G +V+GNCY
Sbjct  409  HEEKLKGRKYLIDAGRQWFELWVPHRPDQWKYPKLVFPDISLKPRFYFDNGGKIVNGNCY  468

Query  476  WIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESI  535
            WI+  KE+  + LFLI G+ NSK M+KYHD+ F NKLY+GRRRY TQYV KYP+PD  S 
Sbjct  469  WIVATKESDVEKLFLIQGVANSKLMTKYHDLVFNNKLYSGRRRYFTQYVEKYPLPDFNSE  528

Query  536  YSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIE  575
             +KEII +V+EL N+  +   I++++N++E  + ++F +E
Sbjct  529  IAKEIIVIVKEL-NHSNDKTVISDLKNQLEIAVAKSFGVE  567


>OWP85851.1 hypothetical protein BWK60_11905 [Flavobacterium columnare]
Length=570

 Score = 473 bits (1218),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 258/577 (45%), Positives = 369/577 (64%), Gaps = 21/577 (4%)

Query  9    TVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSM  68
            T  + K TGA FTP +LA  +A+RI  Y + + NR+   LDPACG+GELL+A+ +V    
Sbjct  3    TKEQIKNTGATFTPKELAVFLAERIASYAQPKNNRI---LDPACGEGELLIAMGEVLNEK  59

Query  69   NIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFL---EMVSEGDNYDLFNIEELE  125
                 L G D +   ++ A +RL   G     L+++DFL   ++ S  +   LF+ E   
Sbjct  60   AFDFSLTGYDANEQYLSFAKDRLFSFGKDKSDLVHEDFLLSVDVSSAQNTPSLFD-ECTS  118

Query  126  PV----DIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIG  181
             V    DI+IANPPYVRTQILG EKAQ L  KFNLKGRVDLY  FL+AMT+ LK  G++G
Sbjct  119  SVNNSFDIVIANPPYVRTQILGTEKAQNLARKFNLKGRVDLYYPFLIAMTESLKEGGLLG  178

Query  182  VITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKEN  241
            VITSNRYL+TK G S RK+L  N+ ILE++DLGD+K FEAAVLPAIF G+KK ++     
Sbjct  179  VITSNRYLSTKSGESVRKYLSENYEILELIDLGDTKLFEAAVLPAIFIGKKKKQKSASSA  238

Query  242  SNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLY-SVEDKTYSISLGKIISPEN  300
            +    F KIYE+ +      ++ E  S+ ++L+ N SG + +   K Y  S G +     
Sbjct  239  N----FIKIYEELNGYKGDLISVE--SVYDVLKNNHSGYFVTTNGKRYKKSSGALKYKIG  292

Query  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360
                W + + +E  W  K+++     +EDF  VKVGIK+TAD VFI   W EL   + PE
Sbjct  293  STTCWEMLSNNESGWIAKIDKATKNRVEDFFKVKVGIKSTADKVFISDKWEELNGTK-PE  351

Query  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420
            D+LL+ +IS +    W+ +      KVLY H   +G+ + +N+E++P+AK Y   H+E+L
Sbjct  352  DELLKELISQENIEPWNAT-DNFELKVLYPHISVNGEKQTVNIEKYPKAKKYFTQHEEKL  410

Query  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480
              RKY++ A R W+E+WVPH P  W  PK++FPD S +P+F++++ G +V+GNCYWI+  
Sbjct  411  KGRKYLIDAGRQWFELWVPHRPDQWKYPKLVFPDISLKPRFYFDNGGKIVNGNCYWIVAT  470

Query  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540
            KE+  + LFLI G+ NSK M+KYHD+ F NKLY+GRRRY TQYV KYP+PD  S  +KEI
Sbjct  471  KESDVEKLFLIQGVANSKLMTKYHDLVFNNKLYSGRRRYFTQYVEKYPLPDFNSEIAKEI  530

Query  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESL  577
            I +V+EL N+  +   I++++N++E  + ++F +E +
Sbjct  531  IVIVKEL-NHSNDKTVISDLKNQLEIAVAKSFGVEPV  566


>WP_114900907.1 modification methylase [Kordia sp. SMS9]
 AXG67844.1 modification methylase PaeR7I [Kordia sp. SMS9]
Length=568

 Score = 465 bits (1197),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 248/567 (44%), Positives = 349/567 (62%), Gaps = 17/567 (3%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQLE  73
            K TGA FTP KLA  +AKRIL Y + ++  ++   DPACGDG LL +I     S   +  
Sbjct  8    KETGATFTPKKLANFLAKRILSYIEIDQPLIV---DPACGDGALLTSIGNQLDSQKRKYS  64

Query  74   LIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNIEELEPV-----D  128
            ++G D + D +  A + L+ +    F L N+DFLE           N EE +       D
Sbjct  65   ILGYDTNFDYLITARKNLTENISSKFHLENEDFLEKTDIDLAQQALNFEENKGAKNNFAD  124

Query  129  IIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRY  188
            IIIANPPYVRTQILGAEKAQ L +K+NLKGRVDLY  FL+AMT  LK  G++GVITSN++
Sbjct  125  IIIANPPYVRTQILGAEKAQFLAKKYNLKGRVDLYYPFLIAMTSALKEGGLVGVITSNKF  184

Query  189  LTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFF  248
            L TK G S RKFL  NF+ILE++DLGD+K F+AAVLPAIF G KK    +  ++   KF 
Sbjct  185  LVTKSGNSIRKFLFENFDILEVIDLGDTKLFDAAVLPAIFIGRKK----KNASNRTAKFL  240

Query  249  KIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWILA  308
            KIYE+++    + +NS    + ++L     G +S   K Y  S G I   +  +  W + 
Sbjct  241  KIYEENNEYTGNFINSV--DVFDILNSKAQGYFSDGLKRYKKSSGIIKFTQTKENNWAML  298

Query  309  TEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPII  368
            ++ E  W  ++  N++  I D   V+VGIKTTAD VFIR  W EL   + PED+ L+ ++
Sbjct  299  SKSEANWVAQIENNSFETIGDSFKVRVGIKTTADKVFIRDSWDELNGNK-PEDENLKELL  357

Query  369  SADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLK  428
            S +    W         KVLY +   +   K ++++++P+ K YLE+H E L  RKYV  
Sbjct  358  SQENIKPWGFC-KKKQLKVLYPYISENSLKKLVDVDQYPKTKKYLEAHSEILKGRKYVTN  416

Query  429  ANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDIL  488
            + R W+EIWVP +P LW  PK++FPD S  P+F++++ G +V+GNCYWI+  ++   D L
Sbjct  417  SGRKWFEIWVPQNPFLWKFPKLVFPDISAVPRFYFDNSGKIVNGNCYWIVATEQKDKDKL  476

Query  489  FLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRELV  548
             LI GI NSK M+KYHD+ F NKLY+GRRRY +QYV  YP+P+  S  S ++I LV+++ 
Sbjct  477  LLIQGISNSKLMTKYHDLVFSNKLYSGRRRYFSQYVQNYPLPNINSPESLDVIRLVKKIN  536

Query  549  NNKKETQDINEIENRIEKLILRAFDIE  575
            N   ET+   ++ + +E L+ + F +E
Sbjct  537  NTSDETK-TKKLVHTLEVLVAKTFGVE  562


>WP_035188037.1 methyltransferase domain-containing protein [Lactobacillus equi]
 KRL78235.1 hypothetical protein FC36_GL001121 [Lactobacillus equi DSM 15833 
= JCM 10991]
Length=560

 Score = 464 bits (1193),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 247/576 (43%), Positives = 361/576 (63%), Gaps = 28/576 (5%)

Query  10   VSRQKATGAHFTPDKLAEVIAKRILDYFKGE-----KNRVIRVLDPACGDGELLLAINKV  64
            ++++K  G  +TPD L+  IA+++  YF  E      N+ +++LDPACGDG LLLA+  V
Sbjct  3    LTQEKKNGIQYTPDDLSLFIAQQLKYYFLRENSDSVSNQKLKLLDPACGDGNLLLAVQNV  62

Query  65   AQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNI---  121
             + ++ Q    G+D D  AI+IA  +L+   H NF+L + D+L ++   +N +LFN    
Sbjct  63   FKDIDYQG--YGIDIDQKAIHIAEGKLN---HNNFKLFSADYLSLIENVENVNLFNQPNS  117

Query  122  --EELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGI  179
               E+  +D+IIANPPY+RT ILGAE++Q L + FNL G+VD+Y  FL AMT  LK NGI
Sbjct  118  LNNEINNIDLIIANPPYIRTSILGAERSQHLAKLFNLSGKVDMYHVFLKAMTNTLKDNGI  177

Query  180  IGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQK  239
            + VITSN+YLT K G + R FL  NF IL I+DLGD+K F AAVLPAIF G+KK      
Sbjct  178  LCVITSNKYLTNKSGKNIRDFLSDNFKILNIIDLGDTKPFSAAVLPAIFIGKKKK---HS  234

Query  240  ENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPE  299
            +NS+VP F ++YE +    S+    + ++L++     K+G++S +  ++ ++ G ++   
Sbjct  235  DNSSVP-FTRVYESASSAKSTDSIDKLSTLLK----EKNGIHSYKGHSFKVTSG-LLDAS  288

Query  300  NYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIP  359
                PW +AT  E EW  K+ +NA+    D   V VGIKTTAD+VFI+ +W +L     P
Sbjct  289  VSDTPWNMATFAEKEWVTKLEKNAHKKFGDVFDVHVGIKTTADNVFIKKNWKDLDTNIRP  348

Query  360  EDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKER  419
            E ++L P++S+    +W      N   +LYTH I++G+   I+  ++P A NYL  HK++
Sbjct  349  EKEVLHPLVSSKTIERWQTH-PDNLNTILYTHTIKNGKRIPIDFYKYPHAYNYLLEHKQQ  407

Query  420  LASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIP  479
            LA R Y+ KA R WYEIWVP  P      K+IFPD S + KF Y+DKG  VDGNCYW+  
Sbjct  408  LAGRSYIKKAKRKWYEIWVPQQPEQLANNKVIFPDISQQAKFVYDDKGYYVDGNCYWLTT  467

Query  480  KKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKE  539
            K + SN+ L L  G+ NS  M KY++I FQN LY+GR+RYLTQYV  Y +PD  + +S++
Sbjct  468  KNDVSNNYLLLATGVANSSIMEKYYNIKFQNVLYSGRKRYLTQYVKNYLLPDINNKHSQK  527

Query  540  IISLVRELVNNKKETQDINEIENRIEKLILRAFDIE  575
            II LV+ +  N  +T+   ++E  I   +  AF+++
Sbjct  528  IIKLVKMICKNPNDTK---KLEKSINSEVQLAFNMQ  560


>CDD19860.1 dNA methyltransferase [Prevotella sp. CAG:732]
Length=558

 Score = 463 bits (1192),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 253/565 (45%), Positives = 351/565 (62%), Gaps = 15/565 (3%)

Query  9    TVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSM  68
            T S  K TGA FTP+ LA  +A++++     E    + VLDPACGDG LL AINKV +  
Sbjct  4    TPSTIKKTGATFTPEGLANFLAEKLITLANSEGMTHLSVLDPACGDGSLLHAINKVGEG-  62

Query  69   NIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNI-EELEPV  127
            N+  +LIG D +   I      L     K+  L  +DFL +    +  DLF++    E  
Sbjct  63   NVD-KLIGYDTNASYIEETKSLLVDKA-KSLELECQDFLTVSP--NRVDLFSVGNRAEFA  118

Query  128  DIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNR  187
            D++IANPPYVRTQ+LGA+K Q+L   FNL G++DLY  FL+AMT  LK  G++GVITSNR
Sbjct  119  DLVIANPPYVRTQVLGAQKTQQLAHDFNLTGKIDLYYPFLMAMTNALKKGGLLGVITSNR  178

Query  188  YLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKF  247
            Y++TK G   RKFLV N+ ILE++DLGD+K F AAVLPAIF G+KK    +   +   K+
Sbjct  179  YISTKSGSDIRKFLVENYEILEVIDLGDTKLFNAAVLPAIFIGKKKKSNKENSQTG--KY  236

Query  248  FKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWIL  307
              IYE  D+ A S      +S+ E+L    +G Y V    YS   GK+  P +    W +
Sbjct  237  ASIYEAEDVNAKSK---SLSSIYEILNEEVTGHYVVGGIEYSYKNGKLKCPMDKTGIWQM  293

Query  308  ATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPI  367
              E+E  W   VN+NA   I+D   V+VGIK+ AD+VFI  +W ++      E +LLRP+
Sbjct  294  TNEEENAWIENVNENAAFRIKDHFKVRVGIKSCADNVFICQEWEKMGLHL--EKELLRPM  351

Query  368  ISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVL  427
            IS +    W ++   + K++LY H   +GQ K  ++ ++P A+ YL+  KE+L +RKYV+
Sbjct  352  ISQENIEAWHINKC-SIKEILYPHYSENGQRKVFDISKYPVAEKYLDKCKEQLEARKYVV  410

Query  428  KANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDI  487
             A R WYE WVP +P LW  PK++FPD S +P+F Y+  G+VV+GNCYWI  + E    +
Sbjct  411  NAGRKWYEYWVPQNPQLWKMPKVVFPDISVKPRFCYDGNGAVVNGNCYWICAQTEEERQL  470

Query  488  LFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVREL  547
            L LI G+ NS+ M KYHD+ F NKLY+GRRRYLTQY+ +YP+PDP + ++++II LV E+
Sbjct  471  LLLIEGVANSELMMKYHDLCFNNKLYSGRRRYLTQYIEQYPMPDPHNKHAQDIIRLVNEI  530

Query  548  VNNKKETQDINEIENRIEKLILRAF  572
             +   E+Q  N IE  I K +  AF
Sbjct  531  NSTDDESQR-NVIEREINKNVNLAF  554


>WP_025017878.1 hypothetical protein [Bacteroides sartorii]
Length=567

 Score = 451 bits (1159),  Expect = 3e-149, Method: Compositional matrix adjust.
 Identities = 241/570 (42%), Positives = 353/570 (62%), Gaps = 16/570 (3%)

Query  8    NTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQS  67
            N +S  K  GA FTP++LA+ ++K+IL       +    VLDPACGDG LL AI K+  +
Sbjct  3    NILSESKKNGATFTPNRLADYLSKKILSTIDPSLSS-FTVLDPACGDGSLLSAICKLGGA  61

Query  68   MNIQLELIGVDFD---IDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNIEEL  124
                  LIG D +   +    ++ +++      NF  I KDFL +     N  + NI+  
Sbjct  62   K--ITSLIGYDTNEEYLKDARLSMQKIDSENKSNF--ICKDFLTICPNVANLYMDNIKN-  116

Query  125  EPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVIT  184
            E  DI+IANPPYVRTQ+LG  KA++L   FNL GRVDLY  F +AMT  LK  GI+GVIT
Sbjct  117  EFADIVIANPPYVRTQVLGTTKAKQLARDFNLTGRVDLYYPFFMAMTNALKKGGILGVIT  176

Query  185  SNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNV  244
            SNRY++TK G   RK+L+ N+ I+EI+DLGD+K F+AAVLPAIF G+KK  E +     V
Sbjct  177  SNRYISTKSGSDIRKYLLDNYEIIEIIDLGDTKLFDAAVLPAIFIGKKK--ETRTLTPKV  234

Query  245  PKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEP  304
             K+  IYE +D +  S + S  N +  +LE +K G Y V ++ Y++ +G +  P + K  
Sbjct  235  GKYMSIYE-TDKDDKSKIESSLNDIYNVLESDKPGNYLVNEQKYTLKIGLLKHPADKKGI  293

Query  305  WILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLL  364
            W ++ + E +W   ++ +    I+D   V+VGIK+ AD+VFI   W +  E    E++LL
Sbjct  294  WQMSDDKENKWIKAIDAHTAFRIKDKFKVRVGIKSCADNVFISQLWDK--EGCKIEEELL  351

Query  365  RPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRK  424
             P+IS +    W++    +   VLY H  ++G+ +  ++E+FP A +YL+ H+E+L SR 
Sbjct  352  CPMISQENIEAWTID-KDSMLHVLYPHYSKNGKRQVFDIEKFPLAFHYLQKHREQLESRN  410

Query  425  YVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENS  484
            Y++KA R WYE WVP +P  W  PK++FPD S  P+F +++ G++V+GNCYWI  + E  
Sbjct  411  YLMKAGRKWYEYWVPQNPDYWKMPKVVFPDISVRPRFCFDESGAIVNGNCYWICAQNEEE  470

Query  485  NDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLV  544
              +L LI G+ NS  M KYHD+ F NKLY+GRRRYL QY+ +YPIP PE   SK+I++LV
Sbjct  471  RSLLLLIEGVSNSSVMIKYHDLCFNNKLYSGRRRYLAQYIEQYPIPSPELESSKQIMALV  530

Query  545  RELVNNKKETQDINEIENRIEKLILRAFDI  574
             +L NN  +  +   + + I+ L+  +F +
Sbjct  531  EKL-NNSSDACEKESLASEIDNLVKISFGV  559


>WP_121123835.1 modification methylase [Sphingobacterium sp. M05W1-28]
 RKO71766.1 modification methylase [Sphingobacterium sp. M05W1-28]
Length=596

 Score = 451 bits (1159),  Expect = 9e-149, Method: Compositional matrix adjust.
 Identities = 244/566 (43%), Positives = 346/566 (61%), Gaps = 19/566 (3%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQLE  73
            K  GA FTP  LA+ +A++IL Y   +    +RVLDP+CGDG LLL+I K   S  I  E
Sbjct  40   KKNGATFTPVLLADFLAEKILKYNTKDS---VRVLDPSCGDGALLLSIGKELVSKKITFE  96

Query  74   LIGVDFDIDAINIANERL-SRSGHKNFRLINKDFLEMVSEGDNY----DLFNIEELEPVD  128
            L GVD + + +  A  RL S  G   + +   DFLE +S  D      +  +++  +  D
Sbjct  97   LRGVDINYNYLRKAETRLESHFGESRYLVQYADFLESISFDDTRFGTSNGISMDMNQCAD  156

Query  129  IIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRY  188
            IIIANPPYVRTQ+LGA  AQ++ +K+ LKG+VDLY  F+ AMT  LK  GI+GVITSN+Y
Sbjct  157  IIIANPPYVRTQLLGAAYAQRISKKYGLKGKVDLYFPFVKAMTFALKEGGILGVITSNKY  216

Query  189  LTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFF  248
            L TK G S R+FL  N+ ILEI+DLGD+K F+AAVLPAIF G K     + +++   +FF
Sbjct  217  LNTKSGESIREFLRENYEILEIIDLGDTKLFDAAVLPAIFIGRKT----RTDSTESCQFF  272

Query  249  KIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWILA  308
            KIY+  D    + +  +  S+ E L+ N  G +   + +Y  + G +    + K  WIL 
Sbjct  273  KIYQ--DFNKKTRLEGKKMSIYEALKNNYVGNFKHNENSYVCTSGAVKFDSSNKSNWILL  330

Query  309  TEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPII  368
               E E+  K+    +  + D   VK+G+KTTAD VFIR DWG     + PE +L+  +I
Sbjct  331  DLREEEFVRKIEAACFSRVRDHFKVKIGVKTTADKVFIRKDWGAYDIIE-PEAELMYDLI  389

Query  369  SADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLK  428
            S +    W       + ++LY H    G+   INLE++PR K YL S+ E L +R YVLK
Sbjct  390  SQENIKAWGTP--ETDLRILYPHFDNKGKCNRINLEDYPRTKEYLLSNFEVLNNRHYVLK  447

Query  429  ANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDIL  488
            + R WYEIWVP +P+LW  PK++FPD S EP+F ++  G +V+GNCYW+    E   DIL
Sbjct  448  SGRGWYEIWVPQNPALWKLPKVVFPDISIEPRFCFDSSGKLVNGNCYWMAATNEKDLDIL  507

Query  489  FLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRELV  548
              I G+CNS+ M+ YH + + NKLYAGR+RY +QY+  YP+P   S   + +++LV++L 
Sbjct  508  LFIQGVCNSRLMNYYHSLMYNNKLYAGRKRYFSQYIENYPLPRFSSANFQAVVALVKQL-  566

Query  549  NNKKETQDINEIENRIEKLILRAFDI  574
             N  ET D +++EN++ KLI  A+ +
Sbjct  567  -NNTETLDKSDLENKLNKLINEAYGL  591


>WP_036861574.1 hypothetical protein [Prevotella melaninogenica]
 KGF56594.1 hypothetical protein HMPREF0661_00880 [Prevotella melaninogenica 
DNF00666]
Length=568

 Score = 449 bits (1154),  Expect = 2e-148, Method: Compositional matrix adjust.
 Identities = 237/570 (42%), Positives = 355/570 (62%), Gaps = 13/570 (2%)

Query  8    NTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQS  67
            NT +  K +GA FTP  LA+ ++++IL   +   + +I VLDPACGDG LL A++++   
Sbjct  3    NTYTEIKKSGATFTPVGLADFLSEKILSQIESSSDELI-VLDPACGDGSLLSAMSRMGGK  61

Query  68   MNIQLELIGVDFDIDAINIANERLSR-SGHKNFRLINKDFLEMVSEGDNYDLFNIEELEP  126
                + LIG D +   +  A   +++ SG K  + I +DFL +     N    N+ + E 
Sbjct  62   R--IMSLIGYDTNSKYLEQAEALMNKMSGEKKHKFICEDFLTVCPSVTNLFTENLCQ-EF  118

Query  127  VDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSN  186
             DI+IANPPYVRTQ+LGA +AQ+L   FNL GR+DLY  FL+AMT  LK  GI+GVITSN
Sbjct  119  ADIVIANPPYVRTQVLGAARAQQLAHDFNLTGRIDLYYPFLMAMTNALKKGGILGVITSN  178

Query  187  RYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPK  246
            RY++TK GG  RKFL+ N++I+EI+DLGD+K F AAVLPAIF G+KK   ++  +S V K
Sbjct  179  RYISTKSGGDIRKFLLDNYDIIEIIDLGDTKLFNAAVLPAIFIGKKK--LHKNFSSKVGK  236

Query  247  FFKIYEQSDIEASSSVNS--EFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEP  304
            +  IYE  +   +   N+     ++ ++L   KSG Y+V ++ Y    G +    +    
Sbjct  237  YTSIYEAEETHKNEEGNTMCSHKNIFDILRSEKSGCYAVGEQQYMFKRGLLKHSTDKTSI  296

Query  305  WILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLL  364
            W ++   E +W   +N +A   I+D   V+VGIK+ AD++FI   W +  E    E+ LL
Sbjct  297  WQMSDAHENKWIDTINAHAAFRIKDKFKVRVGIKSCADNIFISQLWDK--EGLEIEETLL  354

Query  365  RPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRK  424
              +IS +    W++    +   VLY H  +DG+ +  ++E+FP A +YL+ H+E+L  RK
Sbjct  355  CSMISQENIEPWAID-KDSMLHVLYPHYSKDGKRQVFDIEKFPLASHYLQRHREQLEERK  413

Query  425  YVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENS  484
            Y++KA R WYE WVP +P+ W  PK++FPD S  P+F +++ G++V+GNCYW+  + E  
Sbjct  414  YLIKAGRKWYEYWVPQNPAFWKMPKVVFPDISVRPRFCFDESGAIVNGNCYWMCAQNEEE  473

Query  485  NDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLV  544
              +L LI G+ NS  M +YHD+ F NKLY+GRRRYL QYV +YP+P P+   SK+I+SLV
Sbjct  474  RSLLLLIEGVSNSSVMVRYHDLCFNNKLYSGRRRYLAQYVEQYPMPSPKLESSKQIVSLV  533

Query  545  RELVNNKKETQDINEIENRIEKLILRAFDI  574
             +L NN  + ++   + + I+ L+  +F I
Sbjct  534  EKL-NNTLDAREKEILASEIDNLVKISFGI  562


>WP_108633097.1 modification methylase [Sphingobacterium sp. M46]
 PUV24762.1 modification methylase [Sphingobacterium sp. M46]
Length=581

 Score = 448 bits (1153),  Expect = 4e-148, Method: Compositional matrix adjust.
 Identities = 244/566 (43%), Positives = 345/566 (61%), Gaps = 19/566 (3%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQLE  73
            K  GA FTP  LAE +A++IL Y   +    + VLDP+CGDG LLL+I K   S  I  E
Sbjct  25   KKNGATFTPVLLAEFLAEKILKYNNKDS---VSVLDPSCGDGALLLSIGKELVSKKITFE  81

Query  74   LIGVDFDIDAINIANERL-SRSGHKNFRLINKDFLEMVSEGDNY----DLFNIEELEPVD  128
            L GVD + + +  A +RL S  G   +++   DFLE +S  D      +  +++  +  D
Sbjct  82   LRGVDINYNYLGKAEKRLESHFGESRYQVQYADFLESISFDDTRFGTSNGISMDMNQCAD  141

Query  129  IIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRY  188
            IIIANPPYVRTQ+LGA+ AQ++ +K+ LKG+VDLY  F+ AMT  LK  GI+GVITSN+Y
Sbjct  142  IIIANPPYVRTQLLGADYAQQISKKYGLKGKVDLYFPFIKAMTFALKEGGILGVITSNKY  201

Query  189  LTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFF  248
            L TK G S R+FL  N+ ILEI+DLGD+K F+AAVLPAIF G K     + +N+   +FF
Sbjct  202  LNTKSGESIREFLRENYEILEIIDLGDTKLFDAAVLPAIFIGRKT----RTDNTESCQFF  257

Query  249  KIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWILA  308
            KIY+  D    +    +  S+ E L+ N  G +   + +Y  + G +    + K  WIL 
Sbjct  258  KIYQ--DFNRKTKPGGKKMSIYEALKNNYVGNFKHNENSYLCTSGTVKFDSSNKSNWILL  315

Query  309  TEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPII  368
               E E+  K+    +  + D   VK+G+KTTAD VFIR DWG     + PE +L+  +I
Sbjct  316  DLREEEFVRKIEAACFSRVRDHFKVKIGVKTTADKVFIRKDWGAYDIIE-PEAELMYDLI  374

Query  369  SADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLK  428
            S +    W       + ++LY H    G+   INLE++PR K YL S+ E L +R YVLK
Sbjct  375  SQENIKAWGAP--KTDLRILYPHFDNKGKRNRINLEDYPRTKEYLLSNFEVLNNRHYVLK  432

Query  429  ANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDIL  488
            + R WYEIWVP +P+LW  PK++FPD S EP+F ++  G +V+GNCYW+    E   DIL
Sbjct  433  SGRGWYEIWVPQNPALWKLPKVVFPDISIEPRFCFDSSGKLVNGNCYWMAATNEKDLDIL  492

Query  489  FLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRELV  548
              I G+CNS+ M+ YH + + NKLYAGR+RY +QY+  YP+P   S   + +++LV++L 
Sbjct  493  LFIQGVCNSRLMNYYHSLMYNNKLYAGRKRYFSQYIENYPLPRFSSANFQAVVALVKQL-  551

Query  549  NNKKETQDINEIENRIEKLILRAFDI  574
             N  ET D  ++EN++ K I  A+ +
Sbjct  552  -NNSETLDKCDLENKLNKFINEAYGL  576


>RYD86055.1 type II restriction endonuclease subunit M [Verrucomicrobiaceae 
bacterium]
Length=580

 Score = 448 bits (1152),  Expect = 6e-148, Method: Compositional matrix adjust.
 Identities = 236/580 (41%), Positives = 354/580 (61%), Gaps = 23/580 (4%)

Query  3    SVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAI-  61
            + ++  TV ++K++GA +TP  LA  +A+R+L+  K     V+R+LDPA GDGEL+L++ 
Sbjct  9    AAKRYETVEQKKSSGATYTPGALATFVARRMLENTKLPSTGVLRILDPAVGDGELVLSLL  68

Query  62   NKVAQSMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMV-SEGDN---Y  116
             ++     +Q+E+ G D D  AI  +  R+S+S  +    L  +DFLE V S+G +    
Sbjct  69   AELKVHSTVQMEVFGFDTDPGAIAESQRRISQSYPNVTLHLSKRDFLEFVLSQGSDRATQ  128

Query  117  DLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKS  176
            +LF+  E E  D+IIANPPYVRTQI+GA++AQ+L   F L GRVDLYQAFL+ M + L+ 
Sbjct  129  NLFSTNEPERFDLIIANPPYVRTQIMGADQAQQLAASFGLGGRVDLYQAFLLGMARVLEP  188

Query  177  NGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKE  236
             G  G+I SNR++TTKGGG  R  L   F + EI DLGD+K F+AAVLPAI     ++K 
Sbjct  189  AGTAGMIVSNRFMTTKGGGLLRSALRQQFALREIWDLGDTKLFDAAVLPAIVIASGQSKR  248

Query  237  YQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKI  295
             ++      KF   YE +D    S+V       +E L     G+  V D +++ I  G +
Sbjct  249  TEEPI----KFSSAYETTDPAVVSAVGP-----VEAL--GHEGVVQVADGRSFDIKHGTL  297

Query  296  ISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPE  355
             S    +E W ++T     W   VNQN +        ++VG+KT AD VFIR DWG    
Sbjct  298  DSIGGDEEIWRISTGVGDAWMATVNQNTWALFGALGKIRVGVKTCADKVFIRHDWGSAFG  357

Query  356  EQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLES  415
            +  PE  LLRP+ +   A ++  ++    ++++Y HE+  GQ +AI+L++ P+ + YLES
Sbjct  358  DDKPE--LLRPLTTHHGAGRFRATVPKKARQIVYPHEVVQGQRRAISLDDNPKTQAYLES  415

Query  416  HKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCY  475
            H+E L +R YVL+  R WYEIWVP DPS W  PK++F D S  P F+ +  GSVV+G+CY
Sbjct  416  HRETLEARTYVLEGGRRWYEIWVPQDPSAWALPKLVFRDISERPTFWIDLDGSVVNGDCY  475

Query  476  WIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESI  535
            W++  ++++ D+L+L   + NS F   ++D  F NKLYAGRRRY+TQYV ++P+P+PE  
Sbjct  476  WLVLNRQDNPDLLWLAAAVANSTFAEAFYDHRFNNKLYAGRRRYITQYVEQFPLPNPELA  535

Query  536  YSKEIISLVRELVN-NKKETQDINEIENRIEKLILRAFDI  574
             SKEI+   + + N N     ++ E+  ++  L+ +AF +
Sbjct  536  TSKEIVERAKAIYNENHSSGSELMEL--KLNDLVWKAFGL  573


>RAS63630.1 TaqI restriction endonuclease [Lechevalieria atacamensis]
Length=569

 Score = 447 bits (1150),  Expect = 7e-148, Method: Compositional matrix adjust.
 Identities = 234/581 (40%), Positives = 345/581 (59%), Gaps = 24/581 (4%)

Query  4    VQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINK  63
            V  A  V R+K  G H+TP +LA  +A+++L Y    K R ++VLDPACGDGELLLAI +
Sbjct  2    VATARQVGREKLEGVHYTPAELAGYVARKLLSYGSFPKGRAVKVLDPACGDGELLLAIAR  61

Query  64   VAQSMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMVSEGDN------Y  116
                  +  EL+G D D +AI +A ERL+ +    +FR    DFL  +++ D       +
Sbjct  62   ELAERGVAAELVGTDTDANAIEVATERLANTIPGVSFRGDVADFLLGLAKIDREQPASLF  121

Query  117  DLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKS  176
            DL +++E E  D+IIANPPYVRTQ LG+E+AQ+L  +F L GRVDLYQAF+ A    L  
Sbjct  122  DLGSVDEEEKFDLIIANPPYVRTQHLGSERAQELGRRFGLTGRVDLYQAFIAAFQSVLDD  181

Query  177  NGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKE  236
            NG  G+I  NR+L TKGG S R+ L S + + EI+DLGD+K F AAVLPAI F      +
Sbjct  182  NGSFGIIVPNRFLVTKGGESIRRLLASRYQVNEIIDLGDTKQFAAAVLPAIVFASNIKVD  241

Query  237  YQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGK-I  295
             QK    +P    IY    +E  +   S   S+ + L+   +G   V   T+++  G+ +
Sbjct  242  SQK----IP-VSSIYS---VETGTQATSTAASIYDALDGTPNGAVQVGTSTWTVERGEVV  293

Query  296  ISPE-NYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELP  354
            + P+  +  PW+  + D   +   V++ +Y    D   ++VG+K+TAD VFIR  W EL 
Sbjct  294  VQPKARFDAPWVSRSSD-LNFLAAVDEASYARFSDLGKIRVGVKSTADKVFIRRSWDELE  352

Query  355  EEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLE  414
                PE +LL P++S+D A +W+     +   +LY +++ + +   +++  FPRA  YLE
Sbjct  353  ARVRPERELLHPLVSSDTAERWNCR--HSALSILYPYDMTNRKRVPLDISRFPRAAAYLE  410

Query  415  SHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNC  474
             H+E+L+ RKYV+ A R+W+EIWVP  P+ W  PKI+FPD S   KF  +  G++V+GNC
Sbjct  411  LHREQLSGRKYVIDAGRHWWEIWVPQKPADWAAPKIVFPDISTNGKFAIDRTGALVNGNC  470

Query  475  YWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPES  534
            YWI    E   D+ +L + + NS    +Y+D  F NKLYAGRRR+++QYV+ +P+PDP +
Sbjct  471  YWISLSPEQ-EDLGYLAVAVANSSLAMRYYDARFGNKLYAGRRRFISQYVDHFPLPDPGN  529

Query  535  IYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIE  575
              +K    L REL   +  T+    +E  +E  +  AF +E
Sbjct  530  PAAKRAAELAREL---EGTTESAPSLEREVEAAVWSAFGLE  567


>WP_112228736.1 methyltransferase domain-containing protein [Lechevalieria atacamensis]
Length=573

 Score = 447 bits (1150),  Expect = 9e-148, Method: Compositional matrix adjust.
 Identities = 234/583 (40%), Positives = 346/583 (59%), Gaps = 24/583 (4%)

Query  2    MSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAI  61
            + V  A  V R+K  G H+TP +LA  +A+++L Y    K R ++VLDPACGDGELLLAI
Sbjct  4    LVVATARQVGREKLEGVHYTPAELAGYVARKLLSYGSFPKGRAVKVLDPACGDGELLLAI  63

Query  62   NKVAQSMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMVSEGDN-----  115
             +      +  EL+G D D +AI +A ERL+ +    +FR    DFL  +++ D      
Sbjct  64   ARELAERGVAAELVGTDTDANAIEVATERLANTIPGVSFRGDVADFLLGLAKIDREQPAS  123

Query  116  -YDLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQL  174
             +DL +++E E  D+IIANPPYVRTQ LG+E+AQ+L  +F L GRVDLYQAF+ A    L
Sbjct  124  LFDLGSVDEEEKFDLIIANPPYVRTQHLGSERAQELGRRFGLTGRVDLYQAFIAAFQSVL  183

Query  175  KSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKN  234
              NG  G+I  NR+L TKGG S R+ L S + + EI+DLGD+K F AAVLPAI F     
Sbjct  184  DDNGSFGIIVPNRFLVTKGGESIRRLLASRYQVNEIIDLGDTKQFAAAVLPAIVFASNIK  243

Query  235  KEYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGK  294
             + QK    +P    IY    +E  +   S   S+ + L+   +G   V   T+++  G+
Sbjct  244  VDSQK----IP-VSSIYS---VETGTQATSTAASIYDALDGTPNGAVQVGTSTWTVERGE  295

Query  295  -IISPE-NYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGE  352
             ++ P+  +  PW+  + D   +   V++ +Y    D   ++VG+K+TAD VFIR  W E
Sbjct  296  VVVQPKARFDAPWVSRSSD-LNFLAAVDEASYARFSDLGKIRVGVKSTADKVFIRRSWDE  354

Query  353  LPEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNY  412
            L     PE +LL P++S+D A +W+     +   +LY +++ + +   +++  FPRA  Y
Sbjct  355  LEARVRPERELLHPLVSSDTAERWNCR--HSALSILYPYDMTNRKRVPLDISRFPRAAAY  412

Query  413  LESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDG  472
            LE H+E+L+ RKYV+ A R+W+EIWVP  P+ W  PKI+FPD S   KF  +  G++V+G
Sbjct  413  LELHREQLSGRKYVIDAGRHWWEIWVPQKPADWAAPKIVFPDISTNGKFAIDRTGALVNG  472

Query  473  NCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDP  532
            NCYWI    E   D+ +L + + NS    +Y+D  F NKLYAGRRR+++QYV+ +P+PDP
Sbjct  473  NCYWISLSPEQ-EDLGYLAVAVANSSLAMRYYDARFGNKLYAGRRRFISQYVDHFPLPDP  531

Query  533  ESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIE  575
             +  +K    L REL   +  T+    +E  +E  +  AF +E
Sbjct  532  GNPAAKRAAELAREL---EGTTESAPSLEREVEAAVWSAFGLE  571


>WP_104380928.1 modification methylase [Sphingobacterium sp. HMA12]
Length=567

 Score = 445 bits (1144),  Expect = 6e-147, Method: Compositional matrix adjust.
 Identities = 243/566 (43%), Positives = 346/566 (61%), Gaps = 19/566 (3%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQLE  73
            K  GA FTP  LA  +A++IL Y   +    +RVLDP+CGDG LLL+I K   S  I  +
Sbjct  11   KKNGATFTPVLLAGFLAEKILKYNTKDS---VRVLDPSCGDGALLLSIGKELISKKIAFQ  67

Query  74   LIGVDFDIDAINIANERL-SRSGHKNFRLINKDFLEMVSEGDN----YDLFNIEELEPVD  128
            L GVD + + ++ A   L S  G    ++   DFLE +S  D         +++  +  D
Sbjct  68   LRGVDINYNYLDKAESMLESYFGGSRCQVQYADFLESISFDDTRFGTTKGISLDMNQCAD  127

Query  129  IIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRY  188
            IIIANPPYVRTQ+LGA  AQ++ +K+ LKG+VDLY  F+ AMT  LK  GI+GVITSN+Y
Sbjct  128  IIIANPPYVRTQLLGANYAQQISKKYGLKGKVDLYFPFIKAMTFALKEGGILGVITSNKY  187

Query  189  LTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFF  248
            L TK G S R+FL  N+ ILEI+DLGD+K F+AAVLPAIF G K     + +N+   +FF
Sbjct  188  LNTKSGESIREFLRENYEILEIIDLGDTKLFDAAVLPAIFIGRKT----RTDNTESCQFF  243

Query  249  KIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWILA  308
            KIY+  D    + +N +  S+ E L+ N  G +   + +Y  + G +    + K  WIL 
Sbjct  244  KIYQ--DFNKKTKLNGKKMSIYEALKNNYIGNFKHNENSYICTSGVVKFDSSNKSNWILL  301

Query  309  TEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPII  368
               E E+  K+    +  ++D   VK+G+KTTAD VFIR DWG     + PE +L+  +I
Sbjct  302  DAGEEEFVRKIEAACFSRVKDHFKVKIGVKTTADKVFIRKDWGAYDTIE-PEAELMYDLI  360

Query  369  SADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLK  428
            S +    W       N ++LY H    G+   INLE++P+ K YL S+ + L +R YVLK
Sbjct  361  SQENIKAWGTP--KTNLRILYPHFDNKGKRHRINLEDYPKTKEYLLSNFDVLNNRDYVLK  418

Query  429  ANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDIL  488
            + R WYEIWVP +P+LW  PK++FPD S EP+F ++  G +V+GNCYW+    E   DIL
Sbjct  419  SGRGWYEIWVPQNPALWKLPKVVFPDISIEPRFCFDPSGKLVNGNCYWMAATNEKDLDIL  478

Query  489  FLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRELV  548
              I G+CNS+ M+ YH + + NKLYAGR+RY +QY+  YP+P   S   + I++LV++L 
Sbjct  479  LFIQGVCNSRLMNYYHSLMYNNKLYAGRKRYFSQYIENYPLPRFSSANFQAIVALVKQL-  537

Query  549  NNKKETQDINEIENRIEKLILRAFDI  574
             N  ET D +++EN++ +LI  A+ +
Sbjct  538  -NNSETLDKSDLENKLNELINEAYGL  562


>PWK91816.1 TaqI restriction endonuclease [Lechevalieria deserti]
Length=569

 Score = 445 bits (1144),  Expect = 6e-147, Method: Compositional matrix adjust.
 Identities = 233/581 (40%), Positives = 346/581 (60%), Gaps = 24/581 (4%)

Query  4    VQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINK  63
            V  A  V R+K  G H+TP +LA  +A+++L Y    K R ++VLDPACGDGELLLAI +
Sbjct  2    VATARQVGREKLEGVHYTPAELAGYVARKLLSYGSFPKGRAVKVLDPACGDGELLLAIAR  61

Query  64   VAQSMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMVSEGDN------Y  116
                  +  EL+G D D +AI +A ERL+ +    +FR    DFL  +++ D+      +
Sbjct  62   ELAERGVAAELVGTDTDANAIEVATERLANTIPGVSFRGDVADFLLGLAKIDSGQPASLF  121

Query  117  DLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKS  176
            DL + +E E  D+IIANPPYVRTQ LG+E+AQ+L  +F L GRVDLYQAF+ A    L+ 
Sbjct  122  DLGSRDEEEKFDLIIANPPYVRTQHLGSERAQELGRRFGLTGRVDLYQAFIAAFQSVLED  181

Query  177  NGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKE  236
            NG  G+I  NR+L TKGG S R+ L S + + EI+DLGD+K F AAVLPAI F      +
Sbjct  182  NGSFGIIVPNRFLVTKGGESIRRLLASRYQVNEIIDLGDTKQFAAAVLPAIVFASNIKVD  241

Query  237  YQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGK-I  295
             QK    +P    IY    +E  +   S   S+ + L+   +G   V   T+++  G+ +
Sbjct  242  SQK----IP-VSSIYS---VETGTQATSTAASIYDALDGTPNGAVQVGPSTWTVERGEVV  293

Query  296  ISPE-NYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELP  354
            + P+  +  PW+  + D   +   V++ +Y    D   ++VG+K+TAD VFIR  W +L 
Sbjct  294  VQPKARFDAPWVSRSSD-LNFLAAVDEASYARFSDLGKIRVGVKSTADKVFIRRSWDDLE  352

Query  355  EEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLE  414
                PE +LL P++S+D A +W+     +   +LY +++ + +   +++  FPRA  YLE
Sbjct  353  ARVRPERELLHPLVSSDTAERWNCR--HSALSILYPYDMTNRKRVPLDISRFPRAAAYLE  410

Query  415  SHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNC  474
             H+E+L+ RKYV+ A R+W+EIWVP  P+ W  PKI+FPD S   KF  +  G++V+GNC
Sbjct  411  LHREQLSGRKYVIDAGRHWWEIWVPQKPADWAAPKIVFPDISTNGKFAIDRTGALVNGNC  470

Query  475  YWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPES  534
            YWI    E   D+ +L + + NS    +Y+D  F NKLYAGRRR+++QYV+ +P+PDP +
Sbjct  471  YWISLSPEQ-EDLGYLAVAVANSSLAMRYYDARFGNKLYAGRRRFISQYVDHFPLPDPGN  529

Query  535  IYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIE  575
              +K    L REL   +  T+    +E  +E  +  AF +E
Sbjct  530  PAAKRAAELAREL---EGTTESAPSLEREVEAAVWSAFGLE  567


>CDA48400.1 type I restriction-modification system methyltransferase subunit 
[Bacteroides stercoris CAG:120]
Length=565

 Score = 444 bits (1143),  Expect = 7e-147, Method: Compositional matrix adjust.
 Identities = 239/576 (41%), Positives = 353/576 (61%), Gaps = 20/576 (3%)

Query  8    NTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQS  67
            + +S  K  GA FTP++LA+ ++K+IL       +    VLDPACGDG LL AI K+  +
Sbjct  3    DILSEIKKNGATFTPNRLADYLSKKILSTIDPSLSS-FTVLDPACGDGSLLSAICKLGGA  61

Query  68   MNIQLELIGVDFDIDAINIANERLSRS-----GHKNFRLINKDFLEMVSEGDNYDLFNIE  122
                L    + +D +   + + RLS          NF  I KDFL +     N+ + NI+
Sbjct  62   KITSL----IGYDTNEEYLKDARLSMQTIDFENKSNF--ICKDFLTVYPNVTNFYMDNIK  115

Query  123  ELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGV  182
              E  DI+IANPPYVRTQ+LG  KA++L   FNL GRVDLY  F +AMT  LK  GI+GV
Sbjct  116  N-EFADIVIANPPYVRTQVLGTTKAKQLARDFNLTGRVDLYYPFFMAMTNALKKGGILGV  174

Query  183  ITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENS  242
            ITSNRY++TK G   RK+L+ N+ I+EI+DLGD+K F+AAVLPAIF G+KK  E +    
Sbjct  175  ITSNRYISTKSGSDIRKYLLDNYEIIEIIDLGDTKLFDAAVLPAIFIGKKK--ETRTLTP  232

Query  243  NVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYK  302
             V K+  IYE +D    S + S  N +  +LE +K G Y V ++ Y++ +G +  P + K
Sbjct  233  KVGKYMSIYE-TDKGDKSKIESSLNDIYNVLESDKPGNYLVNEQKYTLRIGLLKHPADKK  291

Query  303  EPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDK  362
              W ++ + E +W   ++ +    I+D   V+VGIK+ AD+VFI   W +  E    E++
Sbjct  292  GIWQMSDDKENKWIEAIDAHTAFRIKDKFKVRVGIKSCADNVFISQLWDK--EGCKIEEE  349

Query  363  LLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLAS  422
            LL P+IS +   +W++    +   VLY H  ++G+ +  ++E+FP A +YL+ H+E+L  
Sbjct  350  LLCPMISQENIEEWTID-KDSMLHVLYPHYSKNGKRQVFDIEKFPSAFHYLQKHREQLEG  408

Query  423  RKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKE  482
            R Y++KA R WYE WVP +P  W  PK++FPD S  P+F +++ G++V+GNCYW+  + E
Sbjct  409  RNYLMKAGRKWYEYWVPQNPDYWKMPKVVFPDISVRPRFCFDESGAIVNGNCYWMCAQNE  468

Query  483  NSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIIS  542
                +L LI G+ NS  M KYHD+ F NKLY+GRRRYL QY+ +YPIP PE   SK+I++
Sbjct  469  GERSLLLLIEGVSNSSVMIKYHDLCFNNKLYSGRRRYLAQYIEQYPIPSPELESSKQIMA  528

Query  543  LVRELVNNKKETQDINEIENRIEKLILRAFDIESLK  578
            LV +L NN  +  +   + + I+ L+  +F +   +
Sbjct  529  LVEKL-NNSSDACEKESLASEIDNLVKISFGVTDCQ  563


>WP_109632688.1 methyltransferase domain-containing protein [Lechevalieria deserti]
Length=573

 Score = 445 bits (1144),  Expect = 7e-147, Method: Compositional matrix adjust.
 Identities = 233/583 (40%), Positives = 347/583 (60%), Gaps = 24/583 (4%)

Query  2    MSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAI  61
            + V  A  V R+K  G H+TP +LA  +A+++L Y    K R ++VLDPACGDGELLLAI
Sbjct  4    LVVATARQVGREKLEGVHYTPAELAGYVARKLLSYGSFPKGRAVKVLDPACGDGELLLAI  63

Query  62   NKVAQSMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMVSEGDN-----  115
             +      +  EL+G D D +AI +A ERL+ +    +FR    DFL  +++ D+     
Sbjct  64   ARELAERGVAAELVGTDTDANAIEVATERLANTIPGVSFRGDVADFLLGLAKIDSGQPAS  123

Query  116  -YDLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQL  174
             +DL + +E E  D+IIANPPYVRTQ LG+E+AQ+L  +F L GRVDLYQAF+ A    L
Sbjct  124  LFDLGSRDEEEKFDLIIANPPYVRTQHLGSERAQELGRRFGLTGRVDLYQAFIAAFQSVL  183

Query  175  KSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKN  234
            + NG  G+I  NR+L TKGG S R+ L S + + EI+DLGD+K F AAVLPAI F     
Sbjct  184  EDNGSFGIIVPNRFLVTKGGESIRRLLASRYQVNEIIDLGDTKQFAAAVLPAIVFASNIK  243

Query  235  KEYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGK  294
             + QK    +P    IY    +E  +   S   S+ + L+   +G   V   T+++  G+
Sbjct  244  VDSQK----IP-VSSIYS---VETGTQATSTAASIYDALDGTPNGAVQVGPSTWTVERGE  295

Query  295  -IISPE-NYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGE  352
             ++ P+  +  PW+  + D   +   V++ +Y    D   ++VG+K+TAD VFIR  W +
Sbjct  296  VVVQPKARFDAPWVSRSSD-LNFLAAVDEASYARFSDLGKIRVGVKSTADKVFIRRSWDD  354

Query  353  LPEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNY  412
            L     PE +LL P++S+D A +W+     +   +LY +++ + +   +++  FPRA  Y
Sbjct  355  LEARVRPERELLHPLVSSDTAERWNCR--HSALSILYPYDMTNRKRVPLDISRFPRAAAY  412

Query  413  LESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDG  472
            LE H+E+L+ RKYV+ A R+W+EIWVP  P+ W  PKI+FPD S   KF  +  G++V+G
Sbjct  413  LELHREQLSGRKYVIDAGRHWWEIWVPQKPADWAAPKIVFPDISTNGKFAIDRTGALVNG  472

Query  473  NCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDP  532
            NCYWI    E   D+ +L + + NS    +Y+D  F NKLYAGRRR+++QYV+ +P+PDP
Sbjct  473  NCYWISLSPEQ-EDLGYLAVAVANSSLAMRYYDARFGNKLYAGRRRFISQYVDHFPLPDP  531

Query  533  ESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIE  575
             +  +K    L REL   +  T+    +E  +E  +  AF +E
Sbjct  532  GNPAAKRAAELAREL---EGTTESAPSLEREVEAAVWSAFGLE  571


>WP_006347600.1 DNA methyltransferase [Streptomyces tsukubensis]
 EIF91513.1 DNA metyltransferase [Streptomyces tsukubensis NRRL18488]
 TAI43164.1 DNA methyltransferase [Streptomyces tsukubensis]
Length=577

 Score = 442 bits (1138),  Expect = 6e-146, Method: Compositional matrix adjust.
 Identities = 228/565 (40%), Positives = 338/565 (60%), Gaps = 21/565 (4%)

Query  12   RQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQ  71
            R K  G HFTP  LAE +A+R++D     + R +R++DPACGDGELLLA N V  +   +
Sbjct  8    RVKRNGQHFTPQALAEFLAERVVDQLP--RGRSLRIIDPACGDGELLLAANSVLSAEGWE  65

Query  72   L-ELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNIEELEPVDII  130
            + EL+G + D      A  R+S  G    ++   DFLE+  + D Y LF        D++
Sbjct  66   VAELVGCELDPAVAAEAEVRMS--GVIQGKVHVGDFLELAEDADAYGLF--------DLV  115

Query  131  IANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRYLT  190
            I NPPYVRTQ+LGAE +  L  +F LKGRVDL  AF+   T+ L S+G + ++ SNR+LT
Sbjct  116  ITNPPYVRTQVLGAELSNALAARFGLKGRVDLTHAFMNLSTRLLNSSGTLALLCSNRFLT  175

Query  191  TKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFFKI  250
            TK G + R+ L S+F + EI DLGD+K F+AAVLPA+    KK ++   + S   +F ++
Sbjct  176  TKSGENIRRVLDSDFTVREIYDLGDTKLFKAAVLPAVVIAGKKTED--ADASEGARFARV  233

Query  251  YEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWILATE  310
            YE +D+ A      E +S++E +    SG+ SVE K+Y I  G +    +   PW L TE
Sbjct  234  YEATDLAA----EKEVSSVLESITSGASGVVSVEGKSYKIESGSLARGVS-GAPWGLRTE  288

Query  311  DEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPIISA  370
            +  +W   + +  +    + A  +VGIKTTAD+VFI  DW +LP ++ PE ++L P+++ 
Sbjct  289  ESAQWLDGIAEGTWKTFGEIAKTRVGIKTTADAVFIGDDWEDLPSDRRPESEILLPLVTH  348

Query  371  DQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLKAN  430
                 WS+S   +  +VLY +++   + + + +  FP+A  YL  H+ERL  RKYV++  
Sbjct  349  GSVRPWSIS-NESATRVLYPYDLGKVKRELLPMTAFPKAMAYLLGHEERLRGRKYVVEGG  407

Query  431  RNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDILFL  490
            R W+EIWVP  P+LW +PKI+FPD S E +F  +  GSV++G+CYWI      S DI FL
Sbjct  408  RQWFEIWVPQRPALWAQPKIVFPDISEEARFALDTSGSVINGDCYWISFADLPSEDIGFL  467

Query  491  IMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRELVNN  550
            ++ + NSK   +++D    NKLY+G RR++TQYV++ P+PDP +  +   I L REL   
Sbjct  468  MLAVGNSKMGLRFYDTVCGNKLYSGSRRWITQYVDRLPLPDPSNPAAVRAIGLARELSET  527

Query  551  KKETQDINEIENRIEKLILRAFDIE  575
               T+    + +RIE  +  AF  E
Sbjct  528  PWGTEAAETLRSRIESALEEAFSAE  552


>WP_050696484.1 hypothetical protein [Prevotella fusca]
 AKU70529.1 hypothetical protein ADJ77_12365 [Prevotella fusca JCM 17724]
Length=565

 Score = 441 bits (1135),  Expect = 1e-145, Method: Compositional matrix adjust.
 Identities = 237/574 (41%), Positives = 345/574 (60%), Gaps = 16/574 (3%)

Query  8    NTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQS  67
            N +S  K  GA FTP++LA+ ++K+IL       +    VLDPACGDG LL +I K+  +
Sbjct  3    NILSEIKKNGATFTPNRLADYLSKKILSTIDPSLSS-FTVLDPACGDGSLLSSICKLGGA  61

Query  68   MNIQLELIGVDFDIDAINIANERLSRS---GHKNFRLINKDFLEMVSEGDNYDLFNIEEL  124
                     + +D +   + + RLS            I KDFL +     N  + NI+  
Sbjct  62   KITSF----IGYDTNEEYLKDARLSMQTIDSENKCNFICKDFLTVCPNVANLYMDNIKN-  116

Query  125  EPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVIT  184
            E  DI+IANPPYVRTQ+LG  KA++L   FNL GRVDLY  F +AMT  LK  GI+GVIT
Sbjct  117  EFADIVIANPPYVRTQVLGTTKAKQLARDFNLTGRVDLYYPFFMAMTNALKKGGILGVIT  176

Query  185  SNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNV  244
            SNRYL+TK G   RK+L+ N+ I+EI+DLGD+K F+AAVLPAIF G+KK  E       V
Sbjct  177  SNRYLSTKSGSDIRKYLLDNYEIIEIIDLGDTKLFDAAVLPAIFIGKKK--ETHSLTPKV  234

Query  245  PKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEP  304
             K+  IYE +D    S + S  N +  +LE +K G Y V  + Y++ +G +  P + K  
Sbjct  235  GKYMSIYE-TDKGDKSKIESSLNDIYNVLESDKPGNYLVNGQKYTLKIGLLKHPADKKGI  293

Query  305  WILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLL  364
            W ++ + E +W   ++ +    I+D   V+VGIK+ AD+VFI   W +  E    E++LL
Sbjct  294  WQMSDDKENKWIEAIDAHTAFRIKDKFKVRVGIKSCADNVFISQLWDK--EGCKIEEELL  351

Query  365  RPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRK  424
             P+IS +    W++    +  +VLY H  ++G+ +  ++E+ P A +YL+ H+E+L  R 
Sbjct  352  CPMISQENIEAWTID-KDSMLQVLYPHYSKNGKRQVFDIEKLPLAFHYLQKHREQLEGRN  410

Query  425  YVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENS  484
            Y++KA R WYE WVP +P  W  PK++FPD S  P+F +++ G++V+GNCYW+  + E  
Sbjct  411  YLMKAGRKWYEYWVPQNPDFWKMPKVVFPDISVRPRFCFDESGAIVNGNCYWMCAQNEEE  470

Query  485  NDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLV  544
              +L LI G+ NS  M +YHD+ F NKLY+GRRRYL QY+ +YPIP PE   SK+I+SLV
Sbjct  471  RSLLLLIEGVSNSSVMIRYHDLCFNNKLYSGRRRYLAQYIEQYPIPSPELESSKQIMSLV  530

Query  545  RELVNNKKETQDINEIENRIEKLILRAFDIESLK  578
             +L NN  +  +   + + I  L+  +F I   +
Sbjct  531  EKL-NNSSDACEKESLASEINNLVKISFGITDCQ  563


>RJX29416.1 methyltransferase domain-containing protein [Desulfurivibrio 
sp.]
Length=580

 Score = 431 bits (1107),  Expect = 3e-141, Method: Compositional matrix adjust.
 Identities = 239/578 (41%), Positives = 356/578 (62%), Gaps = 23/578 (4%)

Query  10   VSRQKATGAHFTPDKLAEVIAKRILDYFKGE--KNRVIRVLDPACGDGELLLA-INKVAQ  66
            V+R+K+ GA FTP  L++ +AK I+   + E    + +R+LDPA G+GELLL+ I ++ +
Sbjct  14   VTRKKSEGATFTPKDLSDFVAKNIVIAAQNEVMSKKKLRILDPAVGEGELLLSLIGELHK  73

Query  67   SMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMV-SEGDNYDLFNIEE-  123
            S   +LE+ G D D ++++IA  R+ +   + N +L N DFL+ V SE     L+   + 
Sbjct  74   SKKHELEVFGFDQDKESLSIAKSRIEKKFPNINLKLENIDFLDFVISETGQKTLWCASDN  133

Query  124  --LEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIG  181
                  D+IIANPPYVRTQI+GA+KA+KL + FNL GRVDLY AF++ +++ L   G  G
Sbjct  134  STPTSYDLIIANPPYVRTQIMGADKARKLSQNFNLTGRVDLYYAFILGISKVLDPKGTTG  193

Query  182  VITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKEN  241
            +I SNR++TTK GGS RK +++ FN+  I DLGD+K F+ AVLP++            E 
Sbjct  194  IIVSNRFMTTKSGGSVRKAILNQFNLNHIYDLGDTKLFDVAVLPSVLIASGTETPKSLE-  252

Query  242  SNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPEN  300
               PKF  IYE +    + SV  +  S IE   +NK G+ SV D + + +  G +   +N
Sbjct  253  ---PKFTSIYETT----AESVQ-KLESPIE--AINKEGIVSVNDGRVFEVQQGILDVNKN  302

Query  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360
                W + T+    W   V +N+ G   D   ++VG+KT AD VFIRSDW       IPE
Sbjct  303  LSSVWRIHTKSNGTWLSTVRKNSIGSFRDIGKIRVGVKTCADKVFIRSDWNNETSGNIPE  362

Query  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420
              +L P+I+   A ++    + N  ++LY H++ +G+ KAI+LE+ P  K YL  +++ L
Sbjct  363  --VLCPLITHHIARRYKSLSIENQLQILYPHKMLNGKRKAIDLEKVPNTKKYLAKYRQEL  420

Query  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480
             SRKYV++A R WYEIWVP DPS W K K+IF D S EP F+ ++ G VV+G+CYW+   
Sbjct  421  ESRKYVIEAGREWYEIWVPQDPSAWKKTKLIFRDISAEPTFWVDESGGVVNGDCYWLTCN  480

Query  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540
               + D+L+L   I NS F+ +Y+D  F+NKLYAGRRR++TQYV K+P+ DP+S   ++I
Sbjct  481  NGVNLDMLWLAAAIGNSTFIEEYYDHMFKNKLYAGRRRFITQYVEKFPLIDPDSNIGQDI  540

Query  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDIESLK  578
            I LV+E V +  ++Q+   I+  I+ ++ RAF +   K
Sbjct  541  IRLVKE-VYSSIDSQETVGIQEEIDGMVWRAFGLSGKK  577


>OIO98490.1 type II restriction endonuclease subunit M [Anaerolineae bacterium 
CG2_30_64_16]
Length=581

 Score = 430 bits (1105),  Expect = 6e-141, Method: Compositional matrix adjust.
 Identities = 219/585 (37%), Positives = 345/585 (59%), Gaps = 30/585 (5%)

Query  2    MSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYF-KGEKNRVIRVLDPACGDGELLLA  60
            +  ++  TV ++KA GA +TP  LA+ +A++I+++  +   N  +RVLDPA GDGELL++
Sbjct  8    VRARRYTTVPKEKAGGATYTPKILADFVARKIVEFSNQLSLNCPLRVLDPAVGDGELLVS  67

Query  61   I-NKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDF---------LEMV  110
            +  ++A    + +++ G + D  A++IA  RL     + F  +  DF         LE  
Sbjct  68   LLRQLADRPGLSIKVSGFETDQAALSIAAGRLG----QRFPTVEVDFESGSFLEFVLEHF  123

Query  111  SEGDNYDLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAM  170
                N  LF+    E  DI+IANPPYVRTQI+G  +A++L ++F L GRVDLY AF++ +
Sbjct  124  GADGNRSLFSPPVPETYDIVIANPPYVRTQIMGTAQARRLAQQFGLSGRVDLYYAFILGI  183

Query  171  TQQLKSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFG  230
             Q LK  GI G+I SNR++TT+ G S R++L   FNI  + DLGD+K F+AAVLPA+   
Sbjct  184  AQVLKPQGIAGIIVSNRFMTTRSGASVRQYLFKRFNIRHVWDLGDTKLFDAAVLPAVLLV  243

Query  231  EKKNKEYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYS  289
            + KN          P F  IYE S++  +++ +        +  +   G+  V D + + 
Sbjct  244  KGKNGH----KLEAPTFTSIYETSELSNTTATDP-------ITALAGEGVIRVPDGRRFR  292

Query  290  ISLGKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSD  349
            +  GK+ +       W +ATE    W   V  + +G   D   ++VG+KT AD VFIR+D
Sbjct  293  VQHGKLDTSGTSGGVWRIATEAVDTWLATVEAHRWGTFRDIGRIRVGVKTCADKVFIRND  352

Query  350  WGELPEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRA  409
            W  LPE   PE  LL+P+ S   A ++  S+     ++LY HE+  G   A++L ++P +
Sbjct  353  WETLPEAARPE--LLKPLTSHHIARRFKPSISDRPSQILYPHEVVQGHRCAVDLAKYPGS  410

Query  410  KNYLESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSV  469
            + YLE+H+  L +R YV++A R WYEIWVP DP+ W  PK++F D + EP F+ +  GS+
Sbjct  411  RAYLEAHRPALEARSYVIEAGREWYEIWVPQDPNAWALPKLVFRDIAEEPTFWIDLNGSI  470

Query  470  VDGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPI  529
            V+G+CYW+I +K    D+L+L   + NS F+ +++D  F NKLYAGRRR++ QYV K+P+
Sbjct  471  VNGDCYWLICQKPTQTDLLWLAAAVGNSTFVERFYDHRFHNKLYAGRRRFMAQYVEKFPM  530

Query  530  PDPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            PDP+S   + II+  + +      + + N ++N +  ++  AF +
Sbjct  531  PDPQSPLCRAIIAKAKRIYECIP-SPEANRLQNELNTMVWEAFGL  574


>WP_099443011.1 methyltransferase domain-containing protein [Caulobacter sp. 
BP25]
 PHY21121.1 type II restriction endonuclease subunit M [Caulobacter sp. BP25]
Length=577

 Score = 429 bits (1102),  Expect = 1e-140, Method: Compositional matrix adjust.
 Identities = 213/571 (37%), Positives = 332/571 (58%), Gaps = 22/571 (4%)

Query  10   VSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMN  69
            V+  KA GA +TP  LA+ +A++I++      +  +++LDPA GDGEL+LA+ +      
Sbjct  16   VADHKAGGATYTPSALAQFVARKIVENAALVGSPTVQILDPAIGDGELVLALLEQLSGEA  75

Query  70   IQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMV--SEGDNYDLFNIEELEP  126
            +   + G D D +A+ +A +R+  +    + RL    FL+ V         +    E   
Sbjct  76   VTPIVTGFDTDPNAVRLAKQRIKAAFPGVSLRLEQASFLDFVLAQASATLGVSAPREGAE  135

Query  127  VDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSN  186
             D++IANPPYVRTQI+GA+ AQ L + FNL GRVDLY AFL+ + + L+  G  G+I SN
Sbjct  136  FDLVIANPPYVRTQIIGADHAQALGQLFNLSGRVDLYHAFLMGIARVLRPGGAAGIIVSN  195

Query  187  RYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPK  246
            R++TTKGG S R  L ++ ++  I D GD+K F+ AVLPA+              +  P 
Sbjct  196  RFMTTKGGASVRAALRTSMSLRHIWDFGDTKLFDTAVLPAVLLAHGG----PPLETAAPG  251

Query  247  FFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWI  306
            F  IYE      +S+ +      +EL  V  +G     D+ + +  G + +     + W 
Sbjct  252  FTSIYETRRKPTTSAADPV--EAVELSGVVATG----GDRRFEVKHGALDTSGAAHDVWR  305

Query  307  LATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRP  366
            LAT+   +W   + Q+++G   D   V+VG+KT AD +FIR+DW E   E  PE  +L+P
Sbjct  306  LATQSTDDWLRTIAQHSWGVFRDIGKVRVGVKTCADKIFIRTDWSEFEAETRPE--ILKP  363

Query  367  IISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYV  426
            +I+   A ++  +    ++ +LY HE+R G+ +A++L  +P+A+ YLE H+  L +R YV
Sbjct  364  LITHHTAGRFRATPAKKHRSILYPHEVRQGRRRAVDLAHYPKARAYLEQHRAALEARTYV  423

Query  427  LKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSND  486
            ++A RNWYE+WVP DP+ W  PK++F D S  P F+ + +G VV+G+CYW+ PK  NS D
Sbjct  424  MEAGRNWYELWVPQDPAAWPAPKLVFRDISERPTFWVDLEGGVVNGDCYWLAPKAGNSED  483

Query  487  ILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRE  546
            +L+L   + NS F+  ++D  F NKLYAGRRR++TQYV  +P+PDP S   +++I   + 
Sbjct  484  LLWLAAAVANSTFIEVFYDRRFNNKLYAGRRRFITQYVELFPLPDPSSKIGRQLIQHAKA  543

Query  547  LVNNKKETQDIN---EIENRIEKLILRAFDI  574
            +      T D N   E+E  ++ L+ RAF +
Sbjct  544  I----HSTTDPNLALELEGELDGLVWRAFGL  570


>RME48647.1 type II restriction endonuclease subunit M [Deltaproteobacteria 
bacterium]
Length=590

 Score = 429 bits (1103),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 227/577 (39%), Positives = 342/577 (59%), Gaps = 26/577 (5%)

Query  9    TVSRQKATGAHFTPDKLAEVIAKRILDYFKGE--KNRVIRVLDPACGDGELLLAI-NKVA  65
             V+  K+ GA +TP  LA+ +A +I++ F GE   +R +RVLDP  GDGELL+++  ++A
Sbjct  15   AVTEAKSAGATYTPAILADFVASKIVEAF-GEVPTDRPLRVLDPGVGDGELLVSLLRQIA  73

Query  66   QSMNIQLELIGVDFDIDAINIANERLSRSGHKNFR--LINKDFLEMVSE----GDNYDLF  119
            +   + +E+ G + D  A+N+A  RL R    N    L  +DFLE V E      N  L 
Sbjct  74   ERPGLNIEVHGFETDEKALNVATGRL-RQCFPNIEINLKPEDFLEFVLEYFGADGNRSLS  132

Query  120  NIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGI  179
                 +  D+IIANPPYVRTQI+G  +A+ L ++F L GR DL  AF++ M Q ++  G+
Sbjct  133  GPPVPDTYDLIIANPPYVRTQIMGRAQARLLAKQFGLSGRADLCHAFILGMAQVIEPKGV  192

Query  180  IGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQK  239
             G+I SNR++TT+ G   R+ L   FNI  + DLGD+K F+AAVLPA+   E KN+    
Sbjct  193  AGIIVSNRFMTTRAGAPVRRVLCERFNIRHVWDLGDTKLFDAAVLPAVLLVEGKNER---  249

Query  240  ENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISP  298
                 P F  IYE S  E +++V ++      +  +   G+   +D + + +  GK+ + 
Sbjct  250  -KLEAPGFTSIYETS--EPANAVATD-----PIRALAGEGVVVTDDGRHFRVQHGKLDTS  301

Query  299  ENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQI  358
                  W +AT     W   V  + +G   D  +++VG+KT AD VFIRSDW ++PE   
Sbjct  302  GTSDGVWRIATATVDAWLATVEAHTWGTFRDIGNIRVGVKTCADKVFIRSDWQDMPEATR  361

Query  359  PEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKE  418
            PE  LL+P+ +   A ++    +    ++LY HE+  G+ +A+NL  +PR++ YLESH+ 
Sbjct  362  PE--LLKPLTTHHIARRFKPRTLRRPWEILYPHEVVQGRRRAVNLARYPRSRAYLESHRA  419

Query  419  RLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWII  478
             L SRKYV++A R WYEIWVP DPS W  PK+ F D + EP F+ +  GSVV+G+CYWII
Sbjct  420  ALESRKYVIEAGREWYEIWVPQDPSSWRLPKLAFRDIAEEPTFWIDMDGSVVNGDCYWII  479

Query  479  PKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSK  538
             +     D+L+L   + NS FM  ++D  F NKLYAGRRR++TQYV K+P+PDP S   K
Sbjct  480  CRNPGQMDLLWLAAAVGNSTFMESFYDYRFHNKLYAGRRRFITQYVEKFPLPDPHSPLGK  539

Query  539  EIISLVRELVNNKKETQDINEIENRIEKLILRAFDIE  575
             II++ + +     E+   + ++ +++K++  AF  E
Sbjct  540  AIIAMAKRIYKC-IESPGSDRLQKKLDKMVWEAFGFE  575


>RCK79459.1 type II DNA modification methyltransferase [Candidatus Ozemobacter 
sibiricus]
Length=581

 Score = 428 bits (1100),  Expect = 3e-140, Method: Compositional matrix adjust.
 Identities = 226/577 (39%), Positives = 352/577 (61%), Gaps = 30/577 (5%)

Query  10   VSRQKATGAHFTPDKLAEVIAKRILDYFKG-EKNRVIRVLDPACGDGELLLAI-NKVAQS  67
            V  +K+ GA +TP+ LA+ +A+++++ F     +R +RVLDPA GDGELL+++  ++A  
Sbjct  16   VPEEKSGGATYTPNILADFVARKVVEIFDDFPVDRPLRVLDPAIGDGELLVSLLQQIAGR  75

Query  68   MNIQLELIGVDFDIDAINIANERLSRSGHKNFRLIN-----KDFLEMVSE---GD-NYDL  118
              + +++ G + D  A+NIA ERL     K F L+      + FL+ V E   GD N  L
Sbjct  76   PGLDIKVFGFETDPKALNIAAERL----RKLFPLVEVNFQCESFLKFVLEHFGGDGNRSL  131

Query  119  FNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNG  178
            F+    E  D+IIANPPYVRTQI+GA +AQ L ++F L GRVDLY AF++ M + LK  G
Sbjct  132  FSSPVQEAYDLIIANPPYVRTQIMGATQAQLLAQQFGLSGRVDLYYAFVLGMAKVLKPKG  191

Query  179  IIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQ  238
            I G+I SNR+LTTK G S R+ L+  FNI  I DLGD+K F+AAVLPA+   E KN    
Sbjct  192  IAGIIVSNRFLTTKSGASVRQALLERFNIRHIWDLGDTKLFDAAVLPAVLLVEGKNGH--  249

Query  239  KENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIIS  297
                  P F  IY+ S  E +++V ++      +  +   G+ + +D + + +  GK+ +
Sbjct  250  --KLETPTFTSIYQTS--EPANAVATD-----PITALAGEGVIATDDGRQFRVQHGKLDT  300

Query  298  PENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQ  357
                   W +AT+   +W   V+ +++G   D  +++VG+KT AD VFIR+DW ++PE  
Sbjct  301  SGTRDGVWRIATKTVDDWLATVDAHSWGTFGDIGNIRVGVKTCADKVFIRNDWSDMPEAV  360

Query  358  IPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHK  417
             PE  LL+ + +   A ++         ++LY HE+  G+ +A++L ++PR++ YLE+H+
Sbjct  361  RPE--LLKSLTTHHIARRFKPLTSDRPIQILYPHEVVQGRRRAVDLAQYPRSQAYLEAHR  418

Query  418  ERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWI  477
              L  RKYV++A R WYEIWVP  P  W+ PK++F D + EP F+ +  GSVV+G+CYW+
Sbjct  419  PTLQGRKYVIEAGREWYEIWVPQAPDAWNLPKLVFRDIAEEPTFWIDLDGSVVNGDCYWL  478

Query  478  IPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYS  537
            I +     D+L+L  GI NS F+ +++D  F NKLYAGRRR++TQYV K+P+PDP S   
Sbjct  479  ICQNPAQTDLLWLAAGIGNSTFIERFYDHRFHNKLYAGRRRFITQYVEKFPLPDPHSPLG  538

Query  538  KEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            K II+  + +        + ++++  ++ ++   F +
Sbjct  539  KAIIAKAKRIYECTP-APEADQLQKELDAMVWEVFGL  574


>WP_086867621.1 hypothetical protein [Streptomyces viridochromogenes]
Length=578

 Score = 427 bits (1099),  Expect = 4e-140, Method: Compositional matrix adjust.
 Identities = 229/564 (41%), Positives = 333/564 (59%), Gaps = 21/564 (4%)

Query  14   KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQLE  73
            K  G HFTP  LAE +AKR  D+    + R +R++DPACGDGELLLA N V  +   ++E
Sbjct  10   KRNGQHFTPQALAEFLAKRAADHLP--RGRSLRIMDPACGDGELLLAANSVLSAEGWKVE  67

Query  74   -LIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNIEELEPVDIIIA  132
             L+G + D +A   A  R+S    +   +   DFLE+  +   Y LF        D++I 
Sbjct  68   ELVGCELDPEAAAQAEARMSDIAQRQVHV--GDFLELAEDASAYGLF--------DLVIT  117

Query  133  NPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRYLTTK  192
            NPPYVRTQ+LGAE +  L  +F LKGRVDL   F+    + L S+G + ++ SNR+L+TK
Sbjct  118  NPPYVRTQVLGAELSGALAARFGLKGRVDLTHPFVTLSARLLNSSGTLALLCSNRFLSTK  177

Query  193  GGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFFKIYE  252
             G + R+ L S+F + EI DLGD+K F+AAVLPA+    KK ++     S   +F + YE
Sbjct  178  AGDNVRRVLDSDFTVREIYDLGDTKLFKAAVLPAVVVANKKMEDAGTTESV--RFTRAYE  235

Query  253  QSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEPWILATEDE  312
               +    S   E +S++E L  + S + SV  KTY I +G ++   +   PW L TE  
Sbjct  236  SPTL----SAGREKSSVLESLTSSASEVVSVAGKTYEIEVGSLVRGAS-GGPWGLQTEQS  290

Query  313  YEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPIISADQ  372
             +W  +V +  +    + A  +VGIKTTAD+VFIR DWG+LP    PE ++L P+++ + 
Sbjct  291  AQWLNEVEKGTWKTFGEVAKTRVGIKTTADAVFIRDDWGKLPLAMQPEAEILLPLVTHEN  350

Query  373  ANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLKANRN  432
               W VS   +  +VLY + +   + + + ++ FP A  YL  H+ERL  RKYV++  R 
Sbjct  351  VRSWRVS-NESETRVLYPYNLEKEKREVLQMDAFPLAMAYLLEHEERLRGRKYVIEGGRQ  409

Query  433  WYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDILFLIM  492
            W+EIWVP  P+LW +PKI+FPD S E +F  +  GSVV+G+CYWI      S DI FL++
Sbjct  410  WFEIWVPQRPALWKQPKIVFPDISEEARFALDTSGSVVNGDCYWISLSDLPSEDIGFLML  469

Query  493  GICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRELVNNKK  552
             + NSK   +++D    NKLY+GRRR++TQYVN+ P+P+P S  +  +I L REL    +
Sbjct  470  AVGNSKLGLRFYDTVCGNKLYSGRRRWITQYVNRLPLPNPTSPAAVRVIGLARELSETPR  529

Query  553  ETQDINEIENRIEKLILRAFDIES  576
             T+    ++  IE  +  AF  ES
Sbjct  530  GTEAAERLQREIESALEEAFFTES  553


>SBT08119.1 Type II DNA modification methyltransferase [Candidatus Accumulibacter 
aalborgensis]
Length=581

 Score = 426 bits (1096),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 219/581 (38%), Positives = 345/581 (59%), Gaps = 22/581 (4%)

Query  2    MSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGE-KNRVIRVLDPACGDGELLLA  60
            +S  +   V+ +KA GA +TP  LA+ +A++I         NR IRVLDPA GDGELL++
Sbjct  8    LSSSRYKLVTEEKAEGATYTPKNLADFVAEQIRRAAPVTIGNRTIRVLDPATGDGELLIS  67

Query  61   INKVAQSMNI-QLELIGVDFDIDAINIANERLSRSGHK-NFRLINKDFLEMVSE----GD  114
            +      +    +E+ G + DI A+NIA +R+ +   K    L    FL+ V +     D
Sbjct  68   LLAQFDGLGTGAIEVHGFETDIRAVNIARDRIKQRFPKVALHLAYGSFLDFVLDEVRPHD  127

Query  115  NYDLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQL  174
            +  LF  + +   D+IIANPPYVRTQI+GAE+AQ L  +F L GRVDLY AF+V M   L
Sbjct  128  SGGLFAKDVVPSYDLIIANPPYVRTQIMGAEQAQLLATQFGLAGRVDLYYAFIVGMAYVL  187

Query  175  KSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKN  234
            K  G+ G+I SNR++TTK GG+ R+ +   FN+  + DLGD++ F+AAVLPA+    K +
Sbjct  188  KPGGVGGIIVSNRFMTTKSGGAVRQAIREQFNVRHVWDLGDTRLFDAAVLPAVLLVGKHD  247

Query  235  KEYQKENSNVPKFFKIYEQSDIEASSSVNS-EFNSLIELLEVNKSGLYSVEDKTYSISLG  293
               Q+ ++     +   E+   +A+  + +  F+ ++ + +  +   ++V++ T  IS  
Sbjct  248  GR-QRMSAGFTSIYTSTEKPTQQATDVIAALRFDGVVAIDDGRR---FTVKNGTLDISAA  303

Query  294  KIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGEL  353
                       W +AT     W + V  + +G   D   ++VG+KT AD VFIR+DW ++
Sbjct  304  A-------DAVWRVATAAGDSWLVTVEASTWGRFGDIGKIRVGVKTCADKVFIRTDWDDM  356

Query  354  PEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYL  413
            P E  PE  LLRP+ +   A ++   +    + +LY HE  +GQ +A++L   PRA+ YL
Sbjct  357  PAETRPE--LLRPLTTHHVAQRFRAGVAKKTRHILYPHETVNGQRRAVDLATCPRARAYL  414

Query  414  ESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGN  473
            E H+  L  R YV++  R WYEIWVP DPS WD PK++F D S  P F+ + +GS+V+G+
Sbjct  415  EQHRSTLERRTYVIEGGRQWYEIWVPQDPSSWDVPKLVFRDISEAPTFWLDLEGSIVNGD  474

Query  474  CYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPE  533
            CYW++ KK    D+L+L   + NS F+  ++D +F NKLYAGRRR++TQYV  +P+PDP 
Sbjct  475  CYWLVCKKPEDADLLWLAAAVANSSFIEAFYDHSFNNKLYAGRRRFITQYVEHFPLPDPA  534

Query  534  SIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
               S+ I++L +++      ++ +++I  ++++L+  AF +
Sbjct  535  LPRSRNIVALAKKIYETVGISK-VDDIARQLDQLVWEAFGV  574


>OGI46383.1 type II restriction endonuclease subunit M [Candidatus Muproteobacteria 
bacterium RBG_16_65_34]
Length=578

 Score = 426 bits (1094),  Expect = 3e-139, Method: Compositional matrix adjust.
 Identities = 223/567 (39%), Positives = 335/567 (59%), Gaps = 19/567 (3%)

Query  13   QKATGAHFTPDKLAEVIAKRILDYFKGE-KNRVIRVLDPACGDGELLLAI-NKVAQSMNI  70
            +KA G  +TP  LA+ +A++I+     E +  V+RVLDPA GDGELL+++  ++     +
Sbjct  19   KKAGGETYTPKLLADFVARQIIQTACLETREGVLRVLDPAVGDGELLVSLLAQLKHLPRV  78

Query  71   QLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMVSEG-DNYDLFNIEELEPVD  128
            ++E+ G + +  A  IA  RL          L    FLE V E   N DLF     EP D
Sbjct  79   KIEIYGFETNPQAKTIAAARLQCDFPTVPVHLEELSFLEYVLENFGNSDLFRSRTAEPFD  138

Query  129  IIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRY  188
            +IIANPPYVRTQI+GA +AQ+L  +F L GRVDLY AFL+ M Q L+  G+ G+I SNR+
Sbjct  139  LIIANPPYVRTQIMGAAQAQRLANQFGLIGRVDLYYAFLMGMAQVLRPRGVAGIIVSNRF  198

Query  189  LTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFF  248
            +TTK G + R  +   FN+  + DLGD+K FEAAVLPA+   E +N    +     P F 
Sbjct  199  MTTKSGSAVRSAIRERFNLRHVWDLGDTKLFEAAVLPAVLLVEGRNGHADER----PTFT  254

Query  249  KIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPENYKEPWIL  307
             IYE   I       +EF +L  +  +   G+  + D + Y +  GK+         W +
Sbjct  255  SIYEADQI-------TEFRTLNPIDALEHDGVIEIPDGRRYRVRHGKLDVRGGSDAVWRI  307

Query  308  ATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPI  367
            ATE    W   V  +++G   D   ++VG+KT  D VFIRSDW +LP E  PE  LLR +
Sbjct  308  ATEAGDAWLATVEAHSWGTFRDIGKIRVGVKTCVDKVFIRSDWDDLPAEDRPE--LLRQL  365

Query  368  ISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVL  427
             +   A ++        +++LY HE+++G  +A++LE++PRA+ YLE H+  L +RKYV 
Sbjct  366  TTHHIARRFKARENNGIRRILYPHEVKNGNRQAVDLEQYPRARAYLERHRAALENRKYVT  425

Query  428  KANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDI  487
             A R W+EIWVP DP+ W+ PK++F D S  P F+ +  G++V+G+CYW+I +K N+ D+
Sbjct  426  DAGRKWFEIWVPQDPAAWEVPKLVFRDISDVPMFWIDKAGTIVNGDCYWLIAEKANAEDL  485

Query  488  LFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVREL  547
            L+L + + NS F+  ++D  F NKLYAGRRR++TQYV ++P+P+P+S     II + +  
Sbjct  486  LWLAVAVGNSTFIEAFYDHRFHNKLYAGRRRFITQYVERFPLPNPKSPIGLSIIEMAKA-  544

Query  548  VNNKKETQDINEIENRIEKLILRAFDI  574
              +   T +   +   + +L+ +AF +
Sbjct  545  AYDAVGTDEGERLTVELNRLVWKAFGL  571


>WP_064017490.1 methyltransferase domain-containing protein [Brevibacillus sp. 
SKDU10]
 OAJ74710.1 hypothetical protein AYJ08_08100 [Brevibacillus sp. SKDU10]
Length=570

 Score = 425 bits (1092),  Expect = 5e-139, Method: Compositional matrix adjust.
 Identities = 226/575 (39%), Positives = 352/575 (61%), Gaps = 20/575 (3%)

Query  4    VQKANTVSRQKATGAHFTPDKLAEVIAKRILDYF-KGEKNRVIRVLDPACGDGELLLAIN  62
            + + + V  +KA GA +TP  L++ +A++I+  F +   N+ +R+LDPA GDGELL+++ 
Sbjct  5    LSRYSEVVDRKADGATYTPKALSDFVAEQIIKAFERIPNNKTLRILDPAVGDGELLVSLL  64

Query  63   KVAQSMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMVSEG-DNYDLFN  120
                S + ++ + G D + + + IA +RL          L N DFLE V+E     +LFN
Sbjct  65   NKLVSKHPKIHVYGFDTNKNVLEIAGKRLKEEFPDLALELKNGDFLEFVNENFGEGNLFN  124

Query  121  IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGII  180
               +EP D+IIANPPYVRTQ++G+EK+++L  +F L GRVDLY AF++ M + L   G+ 
Sbjct  125  DSVVEPFDLIIANPPYVRTQVMGSEKSRELAVQFGLSGRVDLYFAFILGMGKALNPTGVA  184

Query  181  GVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKE  240
            G+I SNR++TTK G   RK + + FNI  + D+GD+K F+ AVLP +   + K    +K 
Sbjct  185  GIIVSNRFMTTKSGKPIRKAISNLFNICHVWDMGDTKLFDVAVLPCVMLLKGKLNSGEKA  244

Query  241  NSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPE  299
                  F  IY  +++ A ++  +  ++L      NKSG+  V D + +++  G + +  
Sbjct  245  -----LFSSIYSVNELTAENTAINPIDAL------NKSGIVQVNDGRCFNVQHGYLDNSG  293

Query  300  NYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIP  359
                 W L  ED   W   V +N +    +   ++VG+KTTAD VFIRSDW  + E Q P
Sbjct  294  EIGGVWKLVNEDSDNWLNTVKENTWATFGEIGKIRVGVKTTADKVFIRSDWNSMGENQKP  353

Query  360  EDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKER  419
            E  LL+P+I+   A ++      + K++LY HE+  G+  + +L ++P+AK YLE+H+  
Sbjct  354  E--LLQPLITHHCAQRYKAK--QSVKEILYPHEVVQGKRVSSDLTKYPKAKLYLETHRNT  409

Query  420  LASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIP  479
            L  RKYV++A RNWYEIWVP DP LW  PKI+F D + EP F+ +  GS+V+G+CYW+ P
Sbjct  410  LEGRKYVVEAGRNWYEIWVPQDPELWKLPKIVFRDIAEEPTFWIDFYGSIVNGDCYWLTP  469

Query  480  KKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKE  539
                + + L+L + I NSKF+ K++D  F NKLYAGRRR++TQYV K+P+P+P+   SK+
Sbjct  470  SDPTNIEALWLALAIGNSKFIEKFYDHMFNNKLYAGRRRFITQYVEKFPLPNPDMEISKD  529

Query  540  IISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            II + +++  +   + +  E+E  + KLI  AF +
Sbjct  530  IIKVTKQIY-SLYPSPETTELERMLNKLIYTAFGL  563


>WP_025078928.1 hypothetical protein [Prevotella fusca]
Length=542

 Score = 423 bits (1088),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 224/535 (42%), Positives = 324/535 (61%), Gaps = 15/535 (3%)

Query  47   VLDPACGDGELLLAINKVAQSMNIQLELIGVDFDIDAINIANERLSRS---GHKNFRLIN  103
            VLDPACGDG LL +I K+  +         + +D +   + + RLS            I 
Sbjct  18   VLDPACGDGSLLSSICKLGGAKITSF----IGYDTNEEYLKDARLSMQTIDSENKCNFIC  73

Query  104  KDFLEMVSEGDNYDLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLY  163
            KDFL +     N  + NI+  E  DI+IANPPYVRTQ+LG  KA++L   FNL GRVDLY
Sbjct  74   KDFLTVCPNVANLYMDNIKN-EFADIVIANPPYVRTQVLGTTKAKQLARDFNLTGRVDLY  132

Query  164  QAFLVAMTQQLKSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAV  223
              F +AMT  LK  GI+GVITSNRYL+TK G   RK+L+ N+ I+EI+DLGD+K F+AAV
Sbjct  133  YPFFMAMTNALKKGGILGVITSNRYLSTKSGSDIRKYLLDNYEIIEIIDLGDTKLFDAAV  192

Query  224  LPAIFFGEKKNKEYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSV  283
            LPAIF G+KK  E       V K+  IYE +D    S + S  N +  +LE +K G Y V
Sbjct  193  LPAIFIGKKK--ETHSLTPKVGKYMSIYE-TDKGDKSKIESSLNDIYNVLESDKPGNYLV  249

Query  284  EDKTYSISLGKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADS  343
              + Y++ +G +  P + K  W ++ + E +W   ++ +    I+D   V+VGIK+ AD+
Sbjct  250  NGQKYTLKIGLLKHPADKKGIWQMSDDKENKWIEAIDAHTAFRIKDKFKVRVGIKSCADN  309

Query  344  VFIRSDWGELPEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINL  403
            VFI   W +  E    E++LL P+IS +    W++    +  +VLY H  ++G+ +  ++
Sbjct  310  VFISQLWDK--EGCKIEEELLCPMISQENIEAWTID-KDSMLQVLYPHYSKNGKRQVFDI  366

Query  404  EEFPRAKNYLESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFY  463
            E+ P A +YL+ H+E+L  R Y++KA R WYE WVP +P  W  PK++FPD S  P+F +
Sbjct  367  EKLPLAFHYLQKHREQLEGRNYLMKAGRKWYEYWVPQNPDFWKMPKVVFPDISVRPRFCF  426

Query  464  EDKGSVVDGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQY  523
            ++ G++V+GNCYW+  + E    +L LI G+ NS  M +YHD+ F NKLY+GRRRYL QY
Sbjct  427  DESGAIVNGNCYWMCAQNEEERSLLLLIEGVSNSSVMIRYHDLCFNNKLYSGRRRYLAQY  486

Query  524  VNKYPIPDPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIESLK  578
            + +YPIP PE   SK+I+SLV +L NN  +  +   + + I  L+  +F I   +
Sbjct  487  IEQYPIPSPELESSKQIMSLVEKL-NNSSDACEKESLASEINNLVKISFGITDCQ  540


>WP_124330052.1 type II restriction endonuclease subunit M [Desulfonema ishimotonii]
 GBC62920.1 type II restriction endonuclease subunit M [Desulfonema ishimotonii]
Length=584

 Score = 424 bits (1091),  Expect = 9e-139, Method: Compositional matrix adjust.
 Identities = 220/581 (38%), Positives = 346/581 (60%), Gaps = 19/581 (3%)

Query  4    VQKANTVSRQKATGAHFTPDKLAEVIAKRILDYF--KGEKNRVIRVLDPACGDGELLLAI  61
             ++   VS +KA GA +TP  L++ IA++I+  F  +  K R IR+LDPA GDGELL+++
Sbjct  10   AKRYGAVSEKKAGGATYTPKILSDFIARQIVTAFYEREGKERPIRILDPAVGDGELLVSL  69

Query  62   -NKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHK-NFRLINKDFLEMVSE----GDN  115
             +++ +     + + G + +  A + A++RL     K + RL+  DFL  +S+    G+N
Sbjct  70   LDQLTEKQYENINISGFETNKKAFDTASKRLKHLFPKISIRLMQDDFLAFISKYFESGNN  129

Query  116  YDLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLK  175
            Y LF     E  D+IIANPPYVRTQI+GAE+A+K+   F LKGRVDLY AF++ M + LK
Sbjct  130  YSLFQPTAPETFDLIIANPPYVRTQIMGAEQARKISRCFGLKGRVDLYHAFILGMAKVLK  189

Query  176  SNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNK  235
            S GI G+I SNR++TTK G   R+ +   F+IL I D+GD+K F+AAVLPA+     K  
Sbjct  190  SGGIAGIIVSNRFMTTKSGSDVRRAICGQFDILHIWDMGDTKLFDAAVLPAVLL--LKGC  247

Query  236  EYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKI  295
            + +   +   KF  +YE +  +A   V +   +L +   V   G   +     S+  G +
Sbjct  248  KKRGNQAGPRKFTSVYETTH-DADECVPNPVEALSKNGVVESGGGLRL-----SVQHGTL  301

Query  296  ISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPE  355
             +     + W +AT+    W      + +G   D   ++VG+KT AD VFIRSDW ++  
Sbjct  302  DTGGKAGDVWRIATQASESWIKTAEAHTWGVFRDIGKIRVGVKTCADKVFIRSDWEDMVL  361

Query  356  EQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLES  415
               PE  LLR + +   A ++       N++++Y H    G+  A+NL+++PR + YL  
Sbjct  362  SHHPE--LLRSLTTHHIARRFKADWSKKNRQIVYPHHSLKGKQHAVNLKKYPRTQAYLSQ  419

Query  416  HKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCY  475
            H+E L  RKYV+ A RNWYE+WVP +P LW+ PK++F D + EP F+ + + +VV+G+CY
Sbjct  420  HRETLEGRKYVMAAGRNWYEVWVPQNPELWNMPKLVFRDITKEPTFWIDLEKTVVNGDCY  479

Query  476  WIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESI  535
            W+I +    +D+L+L + I NS+F+  ++D  F NKLYAGRRR+++QYV K+P+P+P   
Sbjct  480  WLICEDPTKDDLLWLALAIGNSEFIKTFYDYRFHNKLYAGRRRFISQYVEKFPLPNPAES  539

Query  536  YSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIES  576
              K+II   +  + N   + +   +E  + +L+ RAF + +
Sbjct  540  IGKKIIETAKR-IYNLIPSSETELLEKELNRLVWRAFGLPA  579


>WP_051340091.1 hypothetical protein [Planktothrix agardhii]
 CUM60227.1 Modification methylase BseCI [Planktothrix agardhii]
Length=583

 Score = 421 bits (1083),  Expect = 2e-137, Method: Compositional matrix adjust.
 Identities = 232/582 (40%), Positives = 357/582 (61%), Gaps = 31/582 (5%)

Query  6    KANTVSRQKATGAHFTPDKLAEVIAKRILDYFKG-EKNRVIRVLDPACGDGELLLAINKV  64
            +   V ++KATG  +TP  L++ +A+ I+    G    R +R+LDPA G+GELL+++ K 
Sbjct  13   RYGAVLKEKATGETYTPKALSDFVAQNIVQTLIGFPIGRPLRILDPAMGEGELLISLLKQ  72

Query  65   A--QSMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMVSEG----DNYD  117
               +   +++E+ G + + DA+NIA  R+ +S  +       KDFLE V E     DN  
Sbjct  73   LLYRCPELEIEVYGFEPNQDALNIAATRVQQSFPNTTTYFKKKDFLEFVIEEFGLIDNEL  132

Query  118  LFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSN  177
            L  +   +  D+IIANPPYVRTQI+GA++A+ L ++F L GRVDLY AF++A++Q LK  
Sbjct  133  LLILNPPDTYDLIIANPPYVRTQIMGADQAKLLAKQFKLSGRVDLYYAFIIAISQVLKPE  192

Query  178  GIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEY  237
            GI G+I SNR++TT+ G S R+ L+  +N+  + DLGD+K F+AAVLPAI   E +    
Sbjct  193  GIAGIIVSNRFMTTRSGASIRRSLLERYNLHSVWDLGDTKLFDAAVLPAIIVAEGR----  248

Query  238  QKENSNVPKFFKIYE---QSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLG  293
            +   +++P F  IYE    S+IE S+ + +          +  +G+  V+D + + +  G
Sbjct  249  KNHQNSLPVFTSIYETDHSSEIEVSTPIQA----------LAHNGVVQVKDGRKFLVQHG  298

Query  294  KIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGEL  353
             + +  +    W ++T+   +W   V+ + YG   D   ++VG+KT AD VFIRSDW  L
Sbjct  299  NLNTNGSLDGVWSISTKTTNQWLATVDSHTYGTFGDIGKIRVGVKTCADKVFIRSDWHNL  358

Query  354  PEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYL  413
            P  + PE  LLRP+ +   A ++    + + K +LY HE   G  +A+NL  +P ++NYL
Sbjct  359  PPVEYPE--LLRPLTTHHIARRFKALELKSPKYILYPHENVQGCRRAVNLSTYPGSRNYL  416

Query  414  ESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGN  473
            E ++  L SR Y+++A R WYEIWV  DP  W++PK+IF D + +P F+ +  GS+V+G+
Sbjct  417  EKNRVVLESRTYLMEAGREWYEIWVSQDPDAWNQPKLIFRDIANKPTFWLDQSGSIVNGD  476

Query  474  CYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPE  533
            CYWI  +K    D+L+L M I NS F+ +++DI+F NKLYAGRRRY+TQYV K+P+P+PE
Sbjct  477  CYWITCQKPEQLDLLWLAMAIANSSFIEQFYDISFNNKLYAGRRRYITQYVEKFPLPNPE  536

Query  534  SIYSKEIISLVRELVNN-KKETQDINEIENRIEKLILRAFDI  574
               SK II+  +E+         DI +IE  +EK+I  AF +
Sbjct  537  QALSKAIIAKAKEVYECIPSPKSDILQIE--LEKMIWNAFGL  576


>RMG80293.1 type II restriction endonuclease subunit M [Chloroflexi bacterium]
Length=576

 Score = 418 bits (1075),  Expect = 2e-136, Method: Compositional matrix adjust.
 Identities = 231/585 (39%), Positives = 354/585 (61%), Gaps = 27/585 (5%)

Query  1    MMSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKG-EKNRVIRVLDPACGDGELLL  59
            M +  +   VS +K+ GA +TP  LA  +A +I++ F     +R +R+LDPA GDGELL+
Sbjct  1    MKAQSRFAFVSEEKSEGATYTPTILANFVASKIVEAFNNFSGDRPLRILDPAVGDGELLI  60

Query  60   AINKVA--QSMNIQLELIGVDFDIDAINIANERLSR---SGHKNFRLINKDFLEMVSE--  112
            ++ +        + +++ G + +  A++ A  RL R       NF    K+FLE V E  
Sbjct  61   SLLRQLLIDQPEVGIKVYGFETNERALDRATWRLKRYFPDIELNFE--EKNFLEFVIEQF  118

Query  113  --GDNYDLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAM  170
                +  LF+ +     D+IIANPPYVRTQI+GA +AQ L ++F L GRVDLY AF++A+
Sbjct  119  GINGSLSLFSSQIQGQYDLIIANPPYVRTQIMGARQAQLLSKQFGLSGRVDLYYAFILAI  178

Query  171  TQQLKSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFG  230
             + LK  GI G+I SNR++TTK G S RK L+  FNIL + DLGD+K F+ AVLPA+   
Sbjct  179  AEVLKPTGIAGIIVSNRFMTTKSGASVRKALLERFNILHVWDLGDTKLFDVAVLPAVLLV  238

Query  231  EKKNKEYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYS  289
            E KN   Q   +    F  IY+ S+  A  + N   ++L E       G+  + D + + 
Sbjct  239  EGKNGHKQGSTA----FTSIYQTSE-AAFKTANDPISALAE------EGVLEISDGRHFY  287

Query  290  ISLGKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSD  349
            +  GK+ + +     W +ATE    W   VN +++G   D   ++VG+KT AD VFIR+D
Sbjct  288  VQHGKLDTGDTPDGVWRIATETIDTWLATVNAHSWGTFRDIGKIRVGVKTCADKVFIRND  347

Query  350  WGELPEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRA  409
            W ELPEE  PE  LL+P+ +   A ++      + +++LYTHE+ +G+ +A++L ++PR+
Sbjct  348  WQELPEELRPE--LLKPVTTHHIARRFKPLTPDHPRQILYTHEVVEGRRRAVDLSKYPRS  405

Query  410  KNYLESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSV  469
            K YLE ++  L  R+YV+KA R WYEIWVP +P  W  PK++F D + +P F+ +  GSV
Sbjct  406  KAYLERYRSLLKGREYVIKAGRAWYEIWVPQNPDAWGFPKLVFRDIAEKPTFWLDLDGSV  465

Query  470  VDGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPI  529
            V+G+CYW+I +     D+L+L   + NS F+  ++D  F NKLYAGRRR++TQYV K+P+
Sbjct  466  VNGDCYWLICENPEQTDLLWLAAAVGNSTFIECFYDRRFHNKLYAGRRRFITQYVEKFPL  525

Query  530  PDPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            PDP S  SK IIS  ++ V     + + + ++ +++ L+ +AF +
Sbjct  526  PDPNSPISKAIISSAKK-VYECTPSSEADLLQKKLDVLVWQAFGL  569


>RJP32541.1 type II restriction endonuclease subunit M [Phycisphaerales bacterium]
Length=581

 Score = 418 bits (1074),  Expect = 3e-136, Method: Compositional matrix adjust.
 Identities = 223/550 (41%), Positives = 333/550 (61%), Gaps = 28/550 (5%)

Query  10   VSRQKATGAHFTPDKLAEVIAKRILDYFKGEKN-RVIRVLDPACGDGELLLAINKVAQ-S  67
            V+ +K  GA +TP  LA+ +A R++D      N R +R+LDPA G+GELL ++  +AQ  
Sbjct  21   VTDEKVGGATYTPAALADFVAARMIDAAGLHHNPRSVRILDPAVGEGELLASL--LAQLP  78

Query  68   MNIQLELIGVDFDIDAINIANERLSRSGHK--NFRLINKDFL----EMVSEGDNYDLFNI  121
             ++++++ G D D  A++    RL RS     +  L   DFL    +M S       F+ 
Sbjct  79   DDVRIDVCGFDTDRRALHSTEARL-RSAFPGVSLDLRTGDFLKFVLDMCSGVGPGLFFDA  137

Query  122  EELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIG  181
               E  D+IIANPPYVRTQ++GA+ AQ+L   F L GRVDLY AFLVA++  L+ +G+ G
Sbjct  138  GAAETFDLIIANPPYVRTQVMGAKHAQRLAATFGLHGRVDLYYAFLVAISMVLRPHGVAG  197

Query  182  VITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKEN  241
            +I SNR++TT+ G + R+ + + FN+ ++ DLGD+K F AAVLPA+  GE KN +   + 
Sbjct  198  IIVSNRFMTTRAGATVRRAIRAGFNLRQVWDLGDTKLFSAAVLPAVLIGEGKNGD---DG  254

Query  242  SNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPEN  300
             NV +F  IYE ++    SS      S+I+ LE   +G+  V D + + +  G + S   
Sbjct  255  GNV-QFTSIYESTEPARHSSA-----SIIDALE--HTGVVEVPDGRRFHVRSGTLDSSSG  306

Query  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360
                W +AT     W   V+ + +    +   ++VG+KT AD VFIR DW +LP+ + PE
Sbjct  307  SSAVWRIATNATDAWLETVSTHTWRRFGEIGKIRVGVKTCADGVFIRDDWDKLPQNERPE  366

Query  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420
              LLRP+I+   A ++        +++LY HE   GQ +A+ L+E+PR+K YL  H+  L
Sbjct  367  --LLRPLITHHVARRFRADESRAGRRILYPHESIGGQRRAVELDEYPRSKAYLTRHRSVL  424

Query  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480
             SR YVL+A R+WYEIWVP DP+ W KPK++F D + EP F+ +  G+VV+G+CYWI  +
Sbjct  425  ESRSYVLEAGRHWYEIWVPQDPATWRKPKLVFRDIAKEPCFWVDFAGAVVNGDCYWIAIE  484

Query  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540
             E+   +L+L   + NS F+  ++D  F NKLYAGRRR++TQYV  +P+P PES  + EI
Sbjct  485  DES---LLWLAAAVANSTFIRSFYDHRFHNKLYAGRRRFITQYVEAFPLPHPESETAAEI  541

Query  541  ISLVRELVNN  550
            I   R + + 
Sbjct  542  IQGARAMYST  551


>TAM48199.1 type II restriction endonuclease subunit M [Gammaproteobacteria 
bacterium]
Length=581

 Score = 417 bits (1073),  Expect = 4e-136, Method: Compositional matrix adjust.
 Identities = 224/574 (39%), Positives = 341/574 (59%), Gaps = 22/574 (4%)

Query  9    TVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNR-VIRVLDPACGDGELLLAINKVA-Q  66
            + + QK +G  +TP+ LA  +A++I      E +  V+RVLDPA G GELL+++     Q
Sbjct  15   SAADQKISGETYTPELLANFVARQIAQAVHLESHTGVLRVLDPAVGSGELLVSLLSELKQ  74

Query  67   SMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMVSE--GD--NYDLFNI  121
               +++E+ G + +  A+  A  RL R        L  ++FLE V E  GD  N DLF+ 
Sbjct  75   RFKLKVEVYGFETNPQALTNAVVRLERGFPDVPVHLEQRNFLEFVLECFGDVRNGDLFHS  134

Query  122  EELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIG  181
            + +EP D+IIANPPYVRTQI+GA++AQ+L  +F L GRVDLY AFLV ++Q LK +G+ G
Sbjct  135  KTVEPFDLIIANPPYVRTQIIGADQAQRLASQFGLVGRVDLYHAFLVGLSQILKPSGVAG  194

Query  182  VITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKEN  241
            +I SNR++TTK G   R  +   FN+ ++ DLGD+K F+AAVLPA+   E +N       
Sbjct  195  IIVSNRFMTTKSGAVVRSTIRERFNLRQVWDLGDTKLFDAAVLPAVLLVEGRNGN----A  250

Query  242  SNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPEN  300
             + P F  IYE  +   S + +      I+ LE    G+  V D + Y +  GK+     
Sbjct  251  VDPPGFISIYETDETAKSKAADP-----IDALE--HEGVVEVPDGRRYLVRHGKLNVTST  303

Query  301  YKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPE  360
                W + T+D   W   V  + +G   D   ++VG+KT AD VFIRSDW +LP +  PE
Sbjct  304  TDAVWRIVTDDSDAWLATVEAHTWGTFRDIGKIRVGVKTCADKVFIRSDWEDLPTDVQPE  363

Query  361  DKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERL  420
              LL  + +   A ++        +++LY HE+ +G  + ++L  +P  + YLE H+  L
Sbjct  364  --LLCSLTTHHIARRFKAQESKKTRRILYPHEVENGNRRVVDLNRYPHTRAYLEQHRPTL  421

Query  421  ASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK  480
              RKYV++A R WYE+WVP DP+ WD PK++F D S EP F+ +  G+VV+G+CYW+I +
Sbjct  422  EGRKYVIEAGRKWYELWVPQDPAAWDVPKLVFRDISDEPVFWIDYAGTVVNGDCYWLITE  481

Query  481  KENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEI  540
            + +S D+L+L + + NS F+  ++D  F NKLYAGRRR++TQYV ++P+PDPES     I
Sbjct  482  EPDSEDLLWLAVAVGNSTFIEAFYDHRFHNKLYAGRRRFITQYVEQFPLPDPESNIGHRI  541

Query  541  ISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            I++ R   +   +     ++ + ++ L+  AF +
Sbjct  542  IAMARAAYDAVGKA-GFEKLADELDSLVWEAFGL  574


>WP_081054411.1 type II restriction endonuclease subunit M [Burkholderia vietnamiensis]
Length=586

 Score = 417 bits (1071),  Expect = 1e-135, Method: Compositional matrix adjust.
 Identities = 218/573 (38%), Positives = 345/573 (60%), Gaps = 15/573 (3%)

Query  8    NTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA-INKVAQ  66
            + V  QK +GA +TP   A  +A+ +L   +  K   IRVLDPA GDG LL A I  +  
Sbjct  17   SNVDAQKFSGATYTPFGFATFVARNMLHVAELPKRGTIRVLDPAVGDGALLDALIRCLPD  76

Query  67   SMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMV-SEGDNYDLFNIEEL  124
            +   ++E+ G D D  AI IA  RL+      +  +  KDFLE V +  ++ DLF   + 
Sbjct  77   ATRKRVEVWGYDTDPAAIEIATARLADDFPGLSVHIEQKDFLEHVLALQNDDDLFADGQQ  136

Query  125  EPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVIT  184
            EP  ++IANPPYVRTQILGAE+AQ L + F L GRVDLY  FL+ +++ L   G+ GVIT
Sbjct  137  EPFHLVIANPPYVRTQILGAEQAQALAQSFGLTGRVDLYYPFLLGISRVLAEGGVTGVIT  196

Query  185  SNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNV  244
            SNR++TTK G + R+ L+S F I+   DLGD+K F+AAVLP++    K   + +  ++  
Sbjct  197  SNRFMTTKSGQAVRRALLSQFQIVHAWDLGDTKLFDAAVLPSVLVA-KGTADTKHPHAAG  255

Query  245  PKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKEP  304
             +F  IYE  D     S     ++L  L  ++ + +   + + + +  G + +  + +  
Sbjct  256  IEFSTIYETKD----PSQAQAQDALAALDSIDDTVVEIADGRRFRVRHGTLDNGGDPEGL  311

Query  305  WILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLL  364
            W +AT     W   V  N +        ++VG+K+TAD VF+RSDW ++P  + PE  LL
Sbjct  312  WRVATSATDTWLATVAANTWEAFRRIGKIRVGVKSTADKVFVRSDWADIPGGR-PE--LL  368

Query  365  RPIISADQANKWSVSL---VGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLA  421
            RP+++   A ++  ++     N K++LY HE+ +G+  A++L  +P+A+ YLE H+E L 
Sbjct  369  RPLLTRHCARRFRAAVPSKAKNVKEILYPHEVVNGRRSAVDLSRYPKAQRYLEEHREVLE  428

Query  422  SRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKK  481
            +R YV++A RNW+E+WVP DPS+W  PK++FPD S +P F+ + +G VV+G CYW+  + 
Sbjct  429  ARTYVIEAGRNWFELWVPQDPSMWPAPKLVFPDISDKPVFWIDTEGGVVNGECYWLCCEH  488

Query  482  ENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEII  541
            E   D+L+L + I NS F+  ++D  F NKLYAGRRR++TQYV ++P+PDP    ++ II
Sbjct  489  EGEEDLLWLALAIANSTFIESFYDHKFNNKLYAGRRRFITQYVEQFPLPDPSRAETQTII  548

Query  542  SLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            ++ ++ V+    + + + +   +++L+   F +
Sbjct  549  AMAKQ-VHTVTPSSEADALAAELDELVWSIFGL  580


>WP_128588433.1 type II restriction endonuclease subunit M [Pseudomonas simiae]
Length=590

 Score = 416 bits (1069),  Expect = 2e-135, Method: Compositional matrix adjust.
 Identities = 223/581 (38%), Positives = 350/581 (60%), Gaps = 19/581 (3%)

Query  5    QKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKV  64
            ++ + V +QK+ GA +TP   A  +A +I+   +      IRVLDPA GDG LL A+ K 
Sbjct  15   RRYSEVDQQKSAGATYTPPDFAAFLADQIVSVAELPVQGKIRVLDPAAGDGALLEALLKR  74

Query  65   AQSMNI-QLELIGVDFDIDAINIANERLSRSGHKNFRLIN-KDFLEMV-SEGDNYDLFNI  121
              +  + ++ + G D D DA+  A+ RL R+      LI  KDFL  V S   + DLF+ 
Sbjct  75   MPADTLSRVSVFGYDTDPDAVVRASSRLQRAFPGVSILIEEKDFLSHVLSLSGDADLFSD  134

Query  122  EELE--PVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGI  179
               +  P D++IANPPYVRTQI+GAE+AQ+L + F L GRVDLY  FL+ +++ L   G+
Sbjct  135  ARTKQMPFDLVIANPPYVRTQIMGAEQAQQLAQSFGLTGRVDLYYPFLLGISRVLSEGGV  194

Query  180  IGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQK  239
             G+ITSNR++TTK G + R+ L+S F I  + DLGD+K F+AAVLPA+   +   KE   
Sbjct  195  TGIITSNRFMTTKSGQAVRRALLSKFIIKHVWDLGDTKLFDAAVLPAVLLAKGTKKELDP  254

Query  240  ENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISP  298
                +  F  IYE  +   ++      +S  E L ++ + + SV D + + +  G + + 
Sbjct  255  CVEGI-VFSTIYESKETAVAN-----LSSAFEALAMSDNTIVSVLDGRNFLVRHGLLDNG  308

Query  299  ENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQI  358
             N +  W ++TE   +W   V++N +        ++VG+K+TAD VF+R+DW +LP  + 
Sbjct  309  ANAEGVWRISTESSDQWLATVDENTWNTFRRVGKIRVGVKSTADKVFVRNDWSDLPGGR-  367

Query  359  PEDKLLRPIISADQANKWSVSLVGNNK---KVLYTHEIRDGQIKAINLEEFPRAKNYLES  415
            PE  LLRP+I+   A ++   +    K   +++Y HE   G  KA++L  +P A  YLE 
Sbjct  368  PE--LLRPLITRHCARQFKACVPSKAKYIKEIMYPHESTSGGRKAVDLSLYPVASRYLEL  425

Query  416  HKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCY  475
            H++ L +R Y++KA R WYE+WVP DP+ W  PKI+FPD S +P F+ + +G +V+G CY
Sbjct  426  HRDVLEARSYLIKAGRAWYELWVPQDPAAWSSPKIVFPDISEKPTFWMDTEGGIVNGECY  485

Query  476  WIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESI  535
            WI  ++E  ND+L+L + + NS F+  ++D  F NKLYAGRRR++TQYV ++P+PDP   
Sbjct  486  WIQCEREEENDLLWLALAVANSTFIEFFYDHRFNNKLYAGRRRFITQYVEQFPLPDPARK  545

Query  536  YSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIES  576
             ++ II+LV+E ++ +  +   N+  + +  L+ + F + +
Sbjct  546  ETQAIINLVKE-IHEELPSSAANQKISELNALVWKVFGLNA  585


>PZR07375.1 type II restriction endonuclease subunit M [Azospirillum brasilense]
Length=582

 Score = 414 bits (1065),  Expect = 6e-135, Method: Compositional matrix adjust.
 Identities = 215/585 (37%), Positives = 341/585 (58%), Gaps = 25/585 (4%)

Query  3    SVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAI-  61
            S ++  + +  K  G  +TP  L++ +A +++D      N  I VLDPA G GELL++I 
Sbjct  11   SSKRYASATNDKLEGVAYTPKVLSDFVANKMIDS-SSLPNEEIHVLDPAVGRGELLVSIL  69

Query  62   NKVAQSMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMV----SEGDNY  116
            +++    + ++ + G D D   +    +RL+ +       L  KDFLE V    S G   
Sbjct  70   SRLVTKTSARILVYGFDTDGVVLAATQQRLAAAFPQVELHLQRKDFLEYVLGQSSIGRTP  129

Query  117  DLFNIEELEPV--DIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQL  174
             LF++   EP+  D+IIANPPYVRTQI+GA++AQKL   F L GRVDLY AFL+ M Q L
Sbjct  130  SLFDVPA-EPIRFDLIIANPPYVRTQIMGADQAQKLASAFGLSGRVDLYHAFLIGMAQVL  188

Query  175  KSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKN  234
            +  G  G+I SNR++TTKGG   R  L + F +  + DLGD+K F+ AVLPA+   E +N
Sbjct  189  RPGGTAGIIVSNRFMTTKGGSDLRAELRNRFALRHVWDLGDTKLFDVAVLPAVLLAEGRN  248

Query  235  KEYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLG  293
                ++ +    F  IYE  D+  S + ++       +  +   G+ +++D + + +  G
Sbjct  249  GHTLEKIA----FTTIYETQDVATSRAPDA-------IAALASPGVVAIDDGRRFHVQHG  297

Query  294  KIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGEL  353
             +       + W +AT+   EW   VN N +    D   ++VG+KT AD +FIRSDW  L
Sbjct  298  TLNDSGPVNDLWRIATDAGDEWLRIVNANTWKRFSDVGKIRVGVKTCADKIFIRSDWSAL  357

Query  354  PEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYL  413
            PE Q PE  LLRP+ +   + ++        +++LY HE+  GQ + I+L  +P ++ YL
Sbjct  358  PEVQRPE--LLRPLTTHHISGRFRAIRSPKAREILYPHEVVGGQRQPIDLSGYPISRAYL  415

Query  414  ESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGN  473
            ESH+  L  R YVL+A R WYEIWVP DP+ W  PK++F D S +P F+ +  GS+V+G+
Sbjct  416  ESHRAALEGRTYVLEAGRRWYEIWVPQDPAAWIAPKLVFRDISDKPTFWIDLDGSIVNGD  475

Query  474  CYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPE  533
            CYW++ + +  ND+L+L   + NS F+  ++D  F NKLY GRRR++TQYV ++P+PDP 
Sbjct  476  CYWMVAEHQADNDLLWLAAAVSNSTFIEAFYDHRFNNKLYGGRRRFITQYVEQFPLPDPS  535

Query  534  SIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIESLK  578
            +  + +I  + +  + ++  +++   +E  ++ L+ +AF ++  K
Sbjct  536  TPLACKITEMAKA-IYDRAGSREAAALETELDPLVWKAFGLQPEK  579


>OQX00972.1 type II restriction endonuclease subunit M [Thiothrix lacustris]
Length=584

 Score = 414 bits (1065),  Expect = 7e-135, Method: Compositional matrix adjust.
 Identities = 224/578 (39%), Positives = 349/578 (60%), Gaps = 31/578 (5%)

Query  3    SVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA-I  61
            S  +  +V+ +KA GA +TP  LA  +A +IL          IR+LDPA G+G LL A +
Sbjct  9    SAPRYTSVTAEKAEGATYTPSSLAHFVATQILQAASIPSQGKIRLLDPAVGNGILLEAML  68

Query  62   NKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHK----NFRLINKDFLEMVSE-GDNY  116
            + + ++   ++E+   D    A++   +RL    HK       L  +DFL +V++ G   
Sbjct  69   DTLPETTRQRVEVFAFDTHQPALHQTRQRLE---HKYPDIKLNLEKRDFLALVADWGRQQ  125

Query  117  DLFNIE-ELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLK  175
            DLF+ +  L+P D+IIANPPYVRTQI+GA++AQ L ++F L GRVDLY  FL+ +++ L 
Sbjct  126  DLFSTKMSLQPFDLIIANPPYVRTQIIGADQAQLLAKQFGLTGRVDLYYPFLLGISRVLA  185

Query  176  SNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNK  235
              G  G+ITSNR++TTK G S R+ L+S F+I  + DLGD+K F+AAVLPA+       +
Sbjct  186  PQGTAGIITSNRFMTTKSGQSVRQALLSCFHIAHVWDLGDTKLFDAAVLPAVLV-VNTMQ  244

Query  236  EYQKENSNVPKFFKIY---EQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISL  292
            +   +N ++P F  IY   E +   A  ++++  N    ++ +   G + ++  T    L
Sbjct  245  QSTSDNKSIP-FSSIYATTEPASTHAKDALSALANPNNSIVSLPDGGCFHIKHGT----L  299

Query  293  GKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGE  352
                SPE     W +A++    W   V  + +G   D   ++VG+KTTAD VFIR DW +
Sbjct  300  DNGDSPEGV---WRVASQSTDAWLDTVTSHTWGTFGDIGKIRVGVKTTADKVFIRHDWAQ  356

Query  353  LPEEQIPEDKLLRPIISADQANKW-SVSLVGNN--KKVLYTHEIRDGQIKAINLEEFPRA  409
            LP   +PE  LLRP+I+      + SV  V  N  K++LY HEI  G+ +A++++++P+A
Sbjct  357  LPNG-VPE--LLRPLITRHWGQPFKSVKPVKANHIKQILYPHEIMQGKRQAVDIKKYPKA  413

Query  410  KNYLESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSV  469
            + YLE++K  L++R YV++A R WYEIWVP DP+ W  PK++FPD +  P F+ +  G +
Sbjct  414  QRYLEANKAVLSARTYVIEAGRQWYEIWVPQDPAAWSAPKLVFPDIAERPTFWLDTDGGI  473

Query  470  VDGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPI  529
            V G CYW+  K     D+L+L + + NS F+  ++D  F NKLYAGRRR++TQYV K+P+
Sbjct  474  VSGECYWLQCKNPADADLLWLALAVANSTFIESFYDHRFNNKLYAGRRRFITQYVEKFPL  533

Query  530  PDPESIYSKEIISLVREL---VNNKKETQDINEIENRI  564
            PDP+ + SK +I L +++   + + K  + I E++ +I
Sbjct  534  PDPDKVESKMLIQLAKDIYATLPSAKAEKLIAELDAKI  571


>WP_085378765.1 hypothetical protein [Paracoccus contaminans]
 ARJ70735.1 hypothetical protein B0A89_05190 [Paracoccus contaminans]
Length=550

 Score = 413 bits (1061),  Expect = 1e-134, Method: Compositional matrix adjust.
 Identities = 228/578 (39%), Positives = 333/578 (58%), Gaps = 37/578 (6%)

Query  1    MMSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA  60
            M   ++   V   K+ GA +TP  LA+ +A RIL        R IRVLDPA G GELLLA
Sbjct  1    MRFTKRYGDVGETKSDGATYTPRALADFVADRILANANLVSGRAIRVLDPAIGHGELLLA  60

Query  61   INKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHK---NFRLINKDFLEMVSEGDNYD  117
            I      ++  +E+ G + D  A+ +A  RLS    +   N RL    FL+ V +     
Sbjct  61   I---LDRIDGPVEVFGFETDHLALAVARRRLSLEHPQAILNLRL--GSFLDHVLDDFAGG  115

Query  118  LFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSN  177
            LF     EP DIIIANPPYVRTQI+GA++AQ+L ++F L GRVDLY AFL+ M   L   
Sbjct  116  LF--ASAEPYDIIIANPPYVRTQIIGADRAQQLAQQFGLTGRVDLYHAFLLGMATVLAPE  173

Query  178  GIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEY  237
            G  G I SNR++TTKGG S R  +++   + E+ DLGD+K F+AAVLPA+        + 
Sbjct  174  GAAGFIVSNRFMTTKGGASARAGMMTGLRLREVYDLGDTKLFDAAVLPAVLIARGAGAK-  232

Query  238  QKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKII  296
                S  P F  IY+  D  A ++        IE   V K G  S++D +T+ +  G + 
Sbjct  233  ----SATPSFVTIYQTKDEPAHTAATP-----IE--AVGKHGAVSIDDGRTFLVQHGTLD  281

Query  297  SPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEE  356
            +  +    W LA+     W   V QNA+G   D   ++VGIKT AD VF       LP++
Sbjct  282  TGGDPFGVWRLASAGVESWLATVEQNAWGTFRDIGKIRVGIKTCADKVF-------LPKK  334

Query  357  QIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESH  416
               E +L RP+ +   A ++      +N+ VLY H+  DG+ +A++L  +P +  YLE H
Sbjct  335  WDCELELHRPLTTHHIARRFRSE--PHNQLVLYPHQAVDGKKQAVDLSLYPASLAYLEQH  392

Query  417  KERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYW  476
            ++ L  R YV++A R WYEIWVP +P+ W  PK++F D S  P F+ + +G+VV+G+CYW
Sbjct  393  RQTLEDRSYVIEAGRQWYEIWVPQNPADWPAPKLVFRDISERPTFWLDLEGTVVNGDCYW  452

Query  477  IIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIY  536
            +        D+L+L +G+ NS F+ +++D+ F NKLYAGRRR++TQYV ++P+PDPES  
Sbjct  453  LT----GDEDLLWLAVGVANSTFIERFYDLRFNNKLYAGRRRFITQYVEQFPLPDPESSG  508

Query  537  SKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            ++EI++  R+L        D   +E RI++++  AF +
Sbjct  509  AREIVTACRDLYARMANGPD-PALEKRIDRMVWSAFGL  545


>WP_118089112.1 type II restriction endonuclease subunit M [Vibrio cholerae]
Length=562

 Score = 411 bits (1057),  Expect = 5e-134, Method: Compositional matrix adjust.
 Identities = 226/568 (40%), Positives = 357/568 (63%), Gaps = 24/568 (4%)

Query  10   VSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMN  69
            VS +K+ GAH+TP KL++ ++++IL   K +K R++ V DPA GDGEL+L++    +S  
Sbjct  11   VSCRKSEGAHYTPTKLSKFVSEKILTKLK-DKERIV-VADPAIGDGELILSLLGSLES-T  67

Query  70   IQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMVSEGDNYDLFNIEELEPVD  128
            + +E+IG D +ID+I ++ +R+S+   +    LI+ DFL+     +N +L     L   D
Sbjct  68   VHVEVIGFDINIDSIELSKKRISKYFPNVKVNLIHGDFLDYCI-NNNSELCK-HNLPKFD  125

Query  129  IIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRY  188
            +IIANPPYVRTQ+LGAE++Q L + F LKGRVD+YQAFL+ M++ L  +G+ GVI SNR+
Sbjct  126  VIIANPPYVRTQVLGAEQSQFLSKNFGLKGRVDIYQAFLIGMSKCLSEDGVAGVIVSNRF  185

Query  189  LTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFF  248
            LTTKG G+ R+ L   + I  I D GD+K FEAAVLPA+     KNK  +       +F 
Sbjct  186  LTTKGAGALRQSLYDLYKIYNIWDFGDTKLFEAAVLPAVILFSLKNKNAETST----EFC  241

Query  249  KIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPENYKEPWIL  307
             IYE S+ EA+    +  ++      ++  G+    + K+Y I  G +    + K+ W +
Sbjct  242  SIYETSE-EATDFSETPVDA------ISHRGVVKCSNGKSYIIKSGLLDYDSSPKDIWRI  294

Query  308  ATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPI  367
               +  +W   V+   +    +   ++VG+KTTAD VFI+  W    EE   E +L++P+
Sbjct  295  KDVESQKWLADVDSKTWATFGEVGKIRVGVKTTADDVFIKESW---VEETGLEPELIKPL  351

Query  368  ISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVL  427
            I+   A ++  S     K++LYTHE  +G+ KAI++E++P +K+YLE H+E+L  RKYV+
Sbjct  352  ITHHVAGRFKQS-DKETKQILYTHETVNGKKKAIDIEKYPVSKSYLEQHREQLEGRKYVI  410

Query  428  KANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK-KENSND  486
            KANRNW+EIWVP +P LW + KI+F D   EP F+ ++K S+V+G+CYW++   +++  D
Sbjct  411  KANRNWFEIWVPQNPQLWLEDKIVFRDICEEPTFWLDEKQSIVNGDCYWMVNDFQKDETD  470

Query  487  ILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRE  546
            IL+LI+ + NSKF+  ++D  F NKLY+ +RR+++QYV ++P+PDP+S  S ++I L + 
Sbjct  471  ILWLILAVANSKFIELFYDTKFNNKLYSNKRRFISQYVEQFPLPDPKSRISLKMIELAKS  530

Query  547  LVNNKKETQDINEIENRIEKLILRAFDI  574
            +   +       E E  +  L+  AF +
Sbjct  531  IF-TESNIHKRTESEKVLNDLVWEAFGL  557


>OJW39010.1 type II restriction endonuclease subunit M [Rhodanobacter sp. 
67-28]
Length=591

 Score = 412 bits (1060),  Expect = 6e-134, Method: Compositional matrix adjust.
 Identities = 217/581 (37%), Positives = 349/581 (60%), Gaps = 20/581 (3%)

Query  5    QKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA-INK  63
            Q+ + V +QK+ GA +TP  LAE +A +++          IR+LDPA GDG LL A I +
Sbjct  17   QRYSQVDQQKSAGATYTPTPLAEFVAHQMVRIASLPSRGAIRILDPAAGDGALLDALIKR  76

Query  64   VAQSMNIQLELIGVDFDIDAINIANERLSRS--GHKNFRLINKDFLEMVS--EGDNYDLF  119
            +  +   ++E+ G D D  AI +A++RL R+  G K   +  ++FL+ V   +G + DLF
Sbjct  77   LPIAARKRVEIFGYDTDPAAIELASQRLRRNFPGLK-ICIEERNFLDHVLNLQGSS-DLF  134

Query  120  NIEELE-PVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNG  178
            +  E + P D++IANPPYVRTQ++GA +AQ+L + F L GR+DLY  FL+ +++ L   G
Sbjct  135  SAREAQVPFDLVIANPPYVRTQVMGARQAQQLAQSFGLTGRIDLYYPFLLGISKVLAEGG  194

Query  179  IIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQ  238
            I GVITSNR++TTK G + R+ L+S F ++ + DLGD+K F+AAVLP++    +   E +
Sbjct  195  IAGVITSNRFMTTKSGQAVRRELLSRFQLVRVWDLGDTKLFDAAVLPSVLLA-RGIAEPR  253

Query  239  KENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISP  298
            +  S+   F  IYE  D   +S+ ++    L  +   + + + +   + + +  G + + 
Sbjct  254  EPQSDRITFSSIYETRDPAQTSASDA----LAAMSADDDTVVTTPNGRHFRVRHGHLDNG  309

Query  299  ENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQI  358
             N    W +AT+   +W   V  + +G       ++VG+K+TAD VFIRSDW  LP+ + 
Sbjct  310  RNVDGIWRIATQTSDQWLAIVEAHTWGIFRRIGKIRVGVKSTADKVFIRSDWDSLPDGR-  368

Query  359  PEDKLLRPIISADQANKWSV---SLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLES  415
            PE  LLR +I+   A ++     S     K++LY HE+  G   A++L+ +P A  YLE 
Sbjct  369  PE--LLRALITRHCARRYKADTPSKASKIKEILYPHEVIGGVRSAVDLDLYPIAARYLEQ  426

Query  416  HKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCY  475
            ++E L +R YV+ A R WYE+WVP DP+ W   K++FPD S +P F+ +  G VV+G CY
Sbjct  427  YREVLEARNYVIAAGRRWYELWVPQDPAAWSSAKLVFPDISEKPVFWMDTDGGVVNGECY  486

Query  476  WIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESI  535
            W+  +KE   D+L+L + + NS F+  ++D  F NKLYAGRRR++TQYV ++P+PDP S 
Sbjct  487  WLKCEKEGEEDLLWLALAVANSTFIEAFYDHRFNNKLYAGRRRFITQYVEQFPLPDPASK  546

Query  536  YSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIES  576
             +K I+ L  + ++    + + + +   ++  + RAF + +
Sbjct  547  EAKAIVELA-QAIHAALPSAEADRLACELDAYVWRAFGLTA  586


>WP_029151739.1 type II restriction endonuclease subunit M [Methylovulum miyakonense]
Length=583

 Score = 412 bits (1058),  Expect = 7e-134, Method: Compositional matrix adjust.
 Identities = 224/560 (40%), Positives = 339/560 (61%), Gaps = 27/560 (5%)

Query  1    MMSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA  60
            + +  + +  ++QKA GA +TP  LA+ +A+++L      K+  IRVLDPA GDG LL  
Sbjct  5    VTTAPRYSDANQQKADGATYTPGILAQFVAEQMLRIASLPKHGKIRVLDPAVGDGVLLAE  64

Query  61   -INKVAQSMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMV-SEGDNYD  117
             I ++      +L+++G D + +A+  A  RL ++  + +  L  KDFLE V S     D
Sbjct  65   LIKQIPLVTRKRLDVVGYDTNPEAVQFAKRRLRQNFPYLHQHLEQKDFLEHVLSIQSCGD  124

Query  118  LFNI-EELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKS  176
            LF I EE EP  +IIANPPYVRTQI+GA +AQ+L + F L GRVDLY  FL+A+ Q L S
Sbjct  125  LFAIGEEQEPFHLIIANPPYVRTQIMGAYQAQQLAKNFGLSGRVDLYYPFLLAIPQVLAS  184

Query  177  NGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKE  236
             GI GVITSNR++TTK G + R+ L+S F IL   DLGD+K F AAVLP++         
Sbjct  185  EGIAGVITSNRFMTTKSGQAVRRELLSRFQILHAWDLGDTKLFGAAVLPSVLLAHGVGAR  244

Query  237  YQKENSNVPKFFKIYEQSD------IEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSI  290
             ++ N+N   +  IYE  D       +A S+  +E N+++ L           + + + I
Sbjct  245  -KRSNNNPIAYSSIYETIDQASLDTPDALSAFAAEDNTVVAL----------PDGRHFRI  293

Query  291  SLGKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDW  350
              G + +  N +  W +AT+    W   V  N +   +    ++VG+K+TAD +FIR DW
Sbjct  294  RHGTLDNTGNSEGVWRIATQATDTWLATVESNTWQTFQRIGKIRVGVKSTADKIFIRHDW  353

Query  351  GELPEEQIPEDKLLRPIISADQANKWSVSLVGNNK---KVLYTHEIRDGQIKAINLEEFP  407
             +LP    PE  LLRP+I+   A ++  ++  N K   K+LY HE+ +    A++L  +P
Sbjct  354  DDLPG-GCPE--LLRPLITRHCARRFKTNVPTNPKHIKKILYPHEVTEYGRSAVDLNRYP  410

Query  408  RAKNYLESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKG  467
            +A +YLE +++ LA+R YV++A R WYE+WVP DP+ W  PK++F D S +P F+ +  G
Sbjct  411  KAAHYLEQYRDVLAARNYVIQAGRQWYELWVPQDPAAWPYPKLVFLDISDKPVFWLDTDG  470

Query  468  SVVDGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKY  527
             +V+G CYW+  + E+  D+L+L + + NS F+  ++D  F NKLYAGRRR++TQYV ++
Sbjct  471  GIVNGECYWLRCENESEQDLLWLALAVANSTFIETFYDHRFNNKLYAGRRRFITQYVEQF  530

Query  528  PIPDPESIYSKEIISLVREL  547
            P+PDP    SK I++L +E+
Sbjct  531  PLPDPNREESKTIVALTKEI  550


>RGP84823.1 type II restriction endonuclease subunit M [Vibrio cholerae]
 RGP90636.1 type II restriction endonuclease subunit M [Vibrio cholerae]
 RGP90967.1 type II restriction endonuclease subunit M [Vibrio cholerae]
 RGP95561.1 type II restriction endonuclease subunit M [Vibrio cholerae]
Length=559

 Score = 411 bits (1056),  Expect = 7e-134, Method: Compositional matrix adjust.
 Identities = 226/568 (40%), Positives = 357/568 (63%), Gaps = 24/568 (4%)

Query  10   VSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMN  69
            VS +K+ GAH+TP KL++ ++++IL   K +K R++ V DPA GDGEL+L++    +S  
Sbjct  8    VSCRKSEGAHYTPTKLSKFVSEKILTKLK-DKERIV-VADPAIGDGELILSLLGSLES-T  64

Query  70   IQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMVSEGDNYDLFNIEELEPVD  128
            + +E+IG D +ID+I ++ +R+S+   +    LI+ DFL+     +N +L     L   D
Sbjct  65   VHVEVIGFDINIDSIELSKKRISKYFPNVKVNLIHGDFLDYCI-NNNSELCK-HNLPKFD  122

Query  129  IIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRY  188
            +IIANPPYVRTQ+LGAE++Q L + F LKGRVD+YQAFL+ M++ L  +G+ GVI SNR+
Sbjct  123  VIIANPPYVRTQVLGAEQSQFLSKNFGLKGRVDIYQAFLIGMSKCLSEDGVAGVIVSNRF  182

Query  189  LTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFF  248
            LTTKG G+ R+ L   + I  I D GD+K FEAAVLPA+     KNK  +       +F 
Sbjct  183  LTTKGAGALRQSLYDLYKIYNIWDFGDTKLFEAAVLPAVILFSLKNKNAETST----EFC  238

Query  249  KIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPENYKEPWIL  307
             IYE S+ EA+    +  ++      ++  G+    + K+Y I  G +    + K+ W +
Sbjct  239  SIYETSE-EATDFSETPVDA------ISHRGVVKCSNGKSYIIKSGLLDYDSSPKDIWRI  291

Query  308  ATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPI  367
               +  +W   V+   +    +   ++VG+KTTAD VFI+  W    EE   E +L++P+
Sbjct  292  KDVESQKWLADVDSKTWATFGEVGKIRVGVKTTADDVFIKESW---VEETGLEPELIKPL  348

Query  368  ISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVL  427
            I+   A ++  S     K++LYTHE  +G+ KAI++E++P +K+YLE H+E+L  RKYV+
Sbjct  349  ITHHVAGRFKQS-DKETKQILYTHETVNGKKKAIDIEKYPVSKSYLEQHREQLEGRKYVI  407

Query  428  KANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPK-KENSND  486
            KANRNW+EIWVP +P LW + KI+F D   EP F+ ++K S+V+G+CYW++   +++  D
Sbjct  408  KANRNWFEIWVPQNPQLWLEDKIVFRDICEEPTFWLDEKQSIVNGDCYWMVNDFQKDETD  467

Query  487  ILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRE  546
            IL+LI+ + NSKF+  ++D  F NKLY+ +RR+++QYV ++P+PDP+S  S ++I L + 
Sbjct  468  ILWLILAVANSKFIELFYDTKFNNKLYSNKRRFISQYVEQFPLPDPKSRISLKMIELAKS  527

Query  547  LVNNKKETQDINEIENRIEKLILRAFDI  574
            +   +       E E  +  L+  AF +
Sbjct  528  IF-TESNIHKRTESEKVLNDLVWEAFGL  554


>OYU47886.1 type II restriction endonuclease subunit M [Rhizobiales bacterium 
PAR1]
Length=580

 Score = 410 bits (1054),  Expect = 3e-133, Method: Compositional matrix adjust.
 Identities = 223/580 (38%), Positives = 337/580 (58%), Gaps = 25/580 (4%)

Query  4    VQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINK  63
             ++  TV   KA GA +TPD LA  +A +I++    E    I +LDPA GDG L+LA+  
Sbjct  10   ARRYETVDAIKAYGATYTPDNLANFVAAKIVENVALEGRDTITILDPAIGDGALVLALLH  69

Query  64   VAQS-MNIQLELIGVDFDIDAINIANERLSRSGHKN-FRLINKDFLEMV-SEGDNYD---  117
              +S  +  L + G D DI A++ A  R+     K    L   +FLE V  E  N D   
Sbjct  70   ALKSKTSATLNVRGFDTDISALDEAARRIRAYFPKTRLELTRGNFLEFVLEENGNMDAPS  129

Query  118  LFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSN  177
            LF+    +  D++IANPPYVRTQI+G+ +AQ+L   F L GRVDLYQAFL+ + Q L  +
Sbjct  130  LFSRNRPQEFDLVIANPPYVRTQIMGSARAQQLANNFGLAGRVDLYQAFLLGIGQVLSPS  189

Query  178  GIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEY  237
            G  G+I SNR++TTKGGG+ R  L   F++ +I DLGD+K F AAVLPA+     K    
Sbjct  190  GAAGMIVSNRFMTTKGGGALRSALRQQFDLRQIWDLGDTKLFSAAVLPAVLIARGK----  245

Query  238  QKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKII  296
             + + + P F  IYE  D     + +      IE L     G+  ++D + +SI  G + 
Sbjct  246  ARPSGDAPSFTAIYEVKDEPTMRAADP-----IEALAFE--GVVEIDDGRRFSIRHGVLD  298

Query  297  SPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEE  356
            +     + W LA++   EW   V+++A+    +   ++VG+KT AD  FIR DW     +
Sbjct  299  ASGQDCDVWRLASQSGDEWMATVDRHAWKRFGEIGKIRVGVKTCADKTFIRHDWETAFGQ  358

Query  357  QIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESH  416
            + PE  LLRP+ +   A ++  +     + +LY HE+  G+ +A+ LE +P+++ YLE H
Sbjct  359  EKPE--LLRPLTTHHGAGRFRATAPKKARAILYPHEVVQGKRQAVPLENYPKSRAYLEEH  416

Query  417  KERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYW  476
            +  L SR YV+ A R WYE+WVP DP  W  PK++F D S  P F+ +  GSVV+G+CYW
Sbjct  417  RTALESRSYVMDAGRRWYELWVPQDPQAWSAPKLVFRDISERPTFWIDLDGSVVNGDCYW  476

Query  477  IIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIY  536
            ++  +++ +++L+L   + NS F   ++D  F NKLYAGRRR++TQYV ++P+PDP    
Sbjct  477  LVASRQDDDNLLWLAAAVANSTFAEAFYDHRFNNKLYAGRRRFITQYVEQFPLPDPTLSL  536

Query  537  SKEIISLVREL--VNNKKETQDINEIENRIEKLILRAFDI  574
            SK+II+  + +   N+  E Q   ++E  ++ LI +AF +
Sbjct  537  SKDIIARAKTIYEANHSAEAQ---KMERELDALIWQAFGL  573


>WP_104318211.1 methyltransferase domain-containing protein [Rathayibacter rathayi]
 PPI74853.1 DNA methyltransferase [Rathayibacter rathayi]
Length=558

 Score = 409 bits (1050),  Expect = 5e-133, Method: Compositional matrix adjust.
 Identities = 212/575 (37%), Positives = 323/575 (56%), Gaps = 40/575 (7%)

Query  13   QKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQ--SMNI  70
            QK  G H+TP  LA+ +A+R+L          +RVLDPACGDGELLLA+ +VA+  ++++
Sbjct  10   QKRHGKHYTPAPLADFLAERLLAQISLAAG-ALRVLDPACGDGELLLALARVARRKNLDV  68

Query  71   QLELIGVDFDIDAINIANERLSRSG------HKNFRLINKDFLEMVSEGDNYDLFNIEEL  124
             LEL+G D D +AI  AN R +  G        NF L+  D L   S             
Sbjct  69   ALELVGFDLDAEAIQTANGRAAALGVPIAFECANF-LVASDLLIAAS-------------  114

Query  125  EPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVIT  184
               D +I+NPPYVRTQ LG + AQ L EK+ L GR+DL   F+      L+  G++ ++ 
Sbjct  115  --FDGVISNPPYVRTQQLGRDTAQLLAEKYGLSGRIDLTHPFVSIAPNLLRPGGVLALLC  172

Query  185  SNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFG-EKKNKEYQKENSN  243
            SNR+L+TK G + R+      + +E+ DLGD+K F AAVLPA+     ++N +     + 
Sbjct  173  SNRFLSTKAGSNMREIFSKTLSPVELYDLGDTKIFGAAVLPAVLIAIRQQNTQVHPRAT-  231

Query  244  VPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKE  303
               F   YE SD    + V+     L E L    SG  + + + + +  G +    +   
Sbjct  232  ---FLSAYE-SDGPPDAPVD-----LFEALSRRTSGRATWDGRVFDVKAGTLTQGASGST  282

Query  304  PWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKL  363
            PW +   DE EW  +++   +      A ++VG+KTTADSVFIR  WG+LP EQ PE+ L
Sbjct  283  PWRMGGTDEAEWLARLDAGTWKTFGQIAKIRVGVKTTADSVFIRDSWGDLPLEQRPEEAL  342

Query  364  LRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASR  423
            L+P+ +     +W          VLY + +   +    ++E++PRA  YLESH+ERL  R
Sbjct  343  LQPLTTHHNIARWRFD--PGALSVLYPYRLDVERRTVPDMEQYPRAMAYLESHRERLEGR  400

Query  424  KYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKEN  483
            KYV  A R W+EIWV   P  W  PK++FPD S  P+F  +  G++V+G+CYWI      
Sbjct  401  KYVTDAGRQWFEIWVAQQPGRWKSPKLVFPDISELPRFALDRSGAIVNGDCYWIAVDDIG  460

Query  484  SNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISL  543
            S+D+  L++G+ NS    +++D    NKLYAGRRR+++QYV+ +PIP+P S+ S  ++  
Sbjct  461  SSDLALLMLGVANSSTAVRFYDHVCGNKLYAGRRRWISQYVSLFPIPEPSSVQSLAVVEF  520

Query  544  VRELVNNKKETQDINEIENRIEKLILRAFDIESLK  578
            VR LV  ++   +  E+   +++L++ AF+ ++ +
Sbjct  521  VRSLVEGERAVTE--EVAEELDQLVIAAFETKATR  553


>OUL86845.1 type II restriction endonuclease subunit M [Paraburkholderia 
hospita]
Length=592

 Score = 409 bits (1052),  Expect = 7e-133, Method: Compositional matrix adjust.
 Identities = 218/579 (38%), Positives = 346/579 (60%), Gaps = 22/579 (4%)

Query  10   VSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA-INKVAQSM  68
            V  QK++GA +TP   A+ +A  ++      K   IRVLDPA GDG LL A I ++  + 
Sbjct  23   VHHQKSSGATYTPPDFADFVAGEMIKAATLPKQGKIRVLDPAVGDGALLDALIKRLPIAA  82

Query  69   NIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMVSE----GDNYDLFNIEE  123
            + +LE++G D D +A+ IA++RL+      + +L  KDFL  V +    GD +   N ++
Sbjct  83   HRRLEVLGYDTDAEALKIASQRLTNDFPALDIQLEQKDFLAHVLDLQGGGDLFSEGNYQK  142

Query  124  LEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVI  183
              P  +IIANPPYVRTQI+GA+ AQ+L + F+L GRVDLY  FL+ ++Q L   GI GVI
Sbjct  143  --PFHLIIANPPYVRTQIMGAKLAQQLAQSFDLTGRVDLYYPFLLGISQVLAEGGITGVI  200

Query  184  TSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSN  243
            TSNR++TTK G + R+ L+S F ++   DLGD+K F+AAVLPA+F     + +     + 
Sbjct  201  TSNRFMTTKSGQAVRRALLSRFQVIHAWDLGDTKLFDAAVLPAVFLARGTSHQALPSANG  260

Query  244  VPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPENYK  302
            V  F  IY+  D     + ++E  + +  L ++   + ++ D +++ +  G + +  +  
Sbjct  261  V-AFSSIYQTQD-----AAHAEAPNPLAALNMDDGTVVAIPDGRSFRVRHGALDNGGDPD  314

Query  303  EPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDK  362
              W +AT+   +W   V  N +        ++VG+K+TAD VFIR DW  +P  + PE  
Sbjct  315  GLWRVATQSGDQWLATVETNTWDTFRRIGKIRVGVKSTADKVFIRHDWESVPGGR-PE--  371

Query  363  LLRPIISADQANKWSVSLVGNNK---KVLYTHEIRDGQIKAINLEEFPRAKNYLESHKER  419
            LLRP+I+   A ++  +   N K   ++LY HE+     +A++L  +P+A  YLE H++ 
Sbjct  372  LLRPLITRHYARRFKAATPSNPKHIKEILYPHEVTLNGRRAVDLRLYPKASTYLEQHRKV  431

Query  420  LASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIP  479
            L +R YV++A R+WYE+WVP DP  W  PKI+FPD S +P F+ +  G +V+G CYW+  
Sbjct  432  LEARTYVIEAGRSWYELWVPQDPGAWAAPKIVFPDISEKPIFWIDTDGGIVNGECYWLGC  491

Query  480  KKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKE  539
            + +   D+L+L + I NS F+  ++D  F NKLYAGRRR++TQYV ++P+ DP    ++ 
Sbjct  492  ENDGEEDLLWLAVAIANSTFIEAFYDHRFNNKLYAGRRRFITQYVEQFPLLDPAKGDTQS  551

Query  540  IISLVRELVNNKKETQDINEIENRIEKLILRAFDIESLK  578
            IIS+ +  ++ K  + + + +   ++  I RAF +E  K
Sbjct  552  IISIAKA-IHAKLPSSEADAMAADLDSRIWRAFGLEREK  589


>WP_122720126.1 type II restriction endonuclease subunit M [Pseudomonas sp. 286]
Length=590

 Score = 409 bits (1052),  Expect = 8e-133, Method: Compositional matrix adjust.
 Identities = 220/576 (38%), Positives = 346/576 (60%), Gaps = 23/576 (4%)

Query  5    QKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKV  64
            ++ + V +QK++GA +TP   A  +A +I+   +      IRVLDPA G+G LL A+ K 
Sbjct  15   RRYSEVDQQKSSGATYTPPGFAAFVADQIVSVAQLPAQGEIRVLDPAAGEGALLEALLKR  74

Query  65   AQSMNI-QLELIGVDFDIDAINIANERLSRSGHKNFRLIN-KDFLEMV-SEGDNYDLF-N  120
              +  + ++ + G D D DA+  A+ RL  +      LI  KDFL  V S   + DLF +
Sbjct  75   MPAGTLSRVSVFGYDTDPDAVVRASARLQSAFPDVSILIEEKDFLSHVLSLSGDADLFSD  134

Query  121  IEELE-PVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGI  179
            +   + P D++IANPPYVRTQ++G E+AQ+L + F L GRVDLY  FL+ +++ L   G+
Sbjct  135  VRTTQMPFDLVIANPPYVRTQVMGTEQAQQLAQSFGLTGRVDLYYPFLLGISRVLSEGGV  194

Query  180  IGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQK  239
             G+ITSNR++TTK G + R+ L+S F I  + DLGD+K F+ AVLPA+   +   KE   
Sbjct  195  TGIITSNRFMTTKSGQAVRRALLSKFRIKHVWDLGDTKLFDTAVLPAVLLAKGTKKELDP  254

Query  240  ENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISP  298
                +  F  IYE  D     +  + F++  + L ++ + + S+ D + + +  G + + 
Sbjct  255  CVEGI-VFSTIYESKD-----NAVANFSNAFDALAMSDNTVVSISDGRNFLVRHGLLDNG  308

Query  299  ENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQI  358
             N +  W ++TE   +W   VN+N +        V+VG+K+TAD VF+R+DW +LP  + 
Sbjct  309  TNAEGLWRISTESSDQWLATVNENTWNTFRRVGKVRVGVKSTADKVFVRNDWSDLPGGR-  367

Query  359  PEDKLLRPIISADQANKWSVSLVGNNK---KVLYTHEIRDGQIKAINLEEFPRAKNYLES  415
            PE  LLRP+I+   A ++        K   +++Y HE   G  +A++L  +P A  YLE 
Sbjct  368  PE--LLRPLITRHCARQFKACTPSKAKYIKEIMYPHESSSGGRRAVDLSLYPAASRYLEL  425

Query  416  HKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCY  475
            H++ L +R Y++KA R WYE+WVP DP+ W  PKI+FPD S +P F+ + +G +V+G CY
Sbjct  426  HRDTLEARTYLIKAGRAWYELWVPQDPASWSSPKIVFPDISEKPTFWMDTEGGIVNGECY  485

Query  476  WIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESI  535
            WI  ++E+ ND+L+L + + NS F+  ++D  F NKLYAGRRR++TQYV ++P+PDP   
Sbjct  486  WIKCEREDENDLLWLALAVANSTFIEFFYDHRFNNKLYAGRRRFITQYVEQFPLPDPARK  545

Query  536  YSKEIISLVR----ELVNNKKETQDINEIENRIEKL  567
             ++ II L +    EL +N  + Q I+E+   + K+
Sbjct  546  ETQAIIDLAKAIHEELPSNAAD-QKISELNALVWKV  580


>WP_086909745.1 type II restriction endonuclease subunit M [Paraburkholderia 
hospita]
Length=589

 Score = 409 bits (1051),  Expect = 1e-132, Method: Compositional matrix adjust.
 Identities = 218/579 (38%), Positives = 345/579 (60%), Gaps = 22/579 (4%)

Query  10   VSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA-INKVAQSM  68
            V  QK++GA +TP   A+ +A  ++      K   IRVLDPA GDG LL A I ++  + 
Sbjct  20   VHHQKSSGATYTPPDFADFVAGEMIKAATLPKQGKIRVLDPAVGDGALLDALIKRLPIAA  79

Query  69   NIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMV----SEGDNYDLFNIEE  123
            + +LE++G D D +A+ IA++RL+      + +L  KDFL  V      GD +   N ++
Sbjct  80   HRRLEVLGYDTDAEALKIASQRLTNDFPALDIQLEQKDFLAHVLDLQGGGDLFSEGNYQK  139

Query  124  LEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVI  183
              P  +IIANPPYVRTQI+GA+ AQ+L + F+L GRVDLY  FL+ ++Q L   GI GVI
Sbjct  140  --PFHLIIANPPYVRTQIMGAKLAQQLAQSFDLTGRVDLYYPFLLGISQVLAEGGITGVI  197

Query  184  TSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSN  243
            TSNR++TTK G + R+ L+S F ++   DLGD+K F+AAVLPA+F     + +     + 
Sbjct  198  TSNRFMTTKSGQAVRRALLSRFQVIHAWDLGDTKLFDAAVLPAVFLARGTSHQALPSANG  257

Query  244  VPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPENYK  302
            V  F  IY+  D     + ++E  + +  L ++   + ++ D +++ +  G + +  +  
Sbjct  258  V-AFSSIYQTQD-----AAHAEAPNPLAALNMDDGTVVAIPDGRSFRVRHGALDNGGDPD  311

Query  303  EPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDK  362
              W +AT+   +W   V  N +        ++VG+K+TAD VFIR DW  +P  + PE  
Sbjct  312  GLWRVATQSGDQWLATVETNTWDTFRRIGKIRVGVKSTADKVFIRHDWESVPGGR-PE--  368

Query  363  LLRPIISADQANKWSVSLVGNNK---KVLYTHEIRDGQIKAINLEEFPRAKNYLESHKER  419
            LLRP+I+   A ++  +   N K   ++LY HE+     +A++L  +P+A  YLE H++ 
Sbjct  369  LLRPLITRHYARRFKAATPSNPKHIKEILYPHEVTLNGRRAVDLRLYPKASTYLEQHRKV  428

Query  420  LASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIP  479
            L +R YV++A R+WYE+WVP DP  W  PKI+FPD S +P F+ +  G +V+G CYW+  
Sbjct  429  LEARTYVIEAGRSWYELWVPQDPGAWAAPKIVFPDISEKPIFWIDTDGGIVNGECYWLGC  488

Query  480  KKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKE  539
            + +   D+L+L + I NS F+  ++D  F NKLYAGRRR++TQYV ++P+ DP    ++ 
Sbjct  489  ENDGEEDLLWLAVAIANSTFIEAFYDHRFNNKLYAGRRRFITQYVEQFPLLDPAKGDTQS  548

Query  540  IISLVRELVNNKKETQDINEIENRIEKLILRAFDIESLK  578
            IIS+ +  ++ K  + + + +   ++  I RAF +E  K
Sbjct  549  IISIAKA-IHAKLPSSEADAMAADLDSRIWRAFGLEREK  586


>ANO50441.1 hypothetical protein BA177_03760 [Woeseia oceani]
Length=576

 Score = 408 bits (1049),  Expect = 1e-132, Method: Compositional matrix adjust.
 Identities = 224/578 (39%), Positives = 344/578 (60%), Gaps = 19/578 (3%)

Query  3    SVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNR-VIRVLDPACGDGELLLAI  61
            ++ +   V  +KATG+ +TP  LA  +A++I+        + V+R+LDPA GDG LL+ +
Sbjct  7    ALNRYGEVPDEKATGSTYTPASLARFVAEQIVAEAGSTLEKPVLRLLDPAVGDGALLIEL  66

Query  62   -NKVAQSMNIQLELIGVDFDIDAINIA--NERLSRSGHKNFRLINKDFLEMV-SEGDNYD  117
              ++ +  + +LE+ G D D +A+ IA  N R       +  LI  +FL++V +  +  D
Sbjct  67   LRQLKKVGSARLEVFGFDTDKNALAIAERNIRSELPDGASLELICANFLDLVLARAEQGD  126

Query  118  LFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSN  177
            +F  +     D++IANPPYVRTQI+GA+ AQ++ ++F L GRVDLY AFL  M   L   
Sbjct  127  MFAEDCYGDFDLLIANPPYVRTQIMGADIAQRIAKQFQLSGRVDLYYAFLAGMKCFLNRG  186

Query  178  GIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEY  237
             I GVI SNR++T K G S RK +  NF I  + DLGD+K F+ AVLPA+      + E 
Sbjct  187  AIAGVIVSNRFMTIKSGTSVRKSIRENFCIRHVWDLGDTKLFDVAVLPAVLL---LSNEQ  243

Query  238  QKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKII  296
            Q  +S+   F  IYE  D EA   V++    L      +K+G+  V D + + +  G++ 
Sbjct  244  QSCSSSDAAFTSIYETKD-EAEILVDNPVEGL------SKNGVVEVSDSRRFRVQQGRLF  296

Query  297  SPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEE  356
            + E     W +ATE    W   V  + +    D   ++VG+KTTAD VFIR DW E  EE
Sbjct  297  TTEKSDGVWRIATEASDCWLETVQAHTWRKFRDIGKIRVGVKTTADKVFIRKDWTE--EE  354

Query  357  QIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESH  416
                 + LRP+ +   AN++         ++LYTHE  DG+ +AI L++ P  K YL  H
Sbjct  355  TEGAIEALRPLTTHLIANRFRPMQEVPTTQILYTHETVDGRRRAIALDDKPHTKAYLLKH  414

Query  417  KERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYW  476
            +E L  R YV KA RNWYEIWVP  P+ ++KPKI+F D S EP F+ +  GS+V+G+CYW
Sbjct  415  RETLERRTYVRKAGRNWYEIWVPQKPADFEKPKIVFRDISQEPVFWLDRNGSIVNGDCYW  474

Query  477  IIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIY  536
            ++ +  +  +IL+L++G+ NS F  +++D +F+N+LYAGRRR++TQYV ++P+PDP S  
Sbjct  475  LVSENGHEEEILWLVLGVANSTFAEEFYDHSFRNQLYAGRRRFITQYVQEFPLPDPASDS  534

Query  537  SKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            SK+I+ + + +       +D +  E ++ +L+ +AF +
Sbjct  535  SKQIVEMAKAIYETTG-MEDTSAQEVQLSQLVYQAFGL  571


>WP_082990274.1 hypothetical protein [Woeseia oceani]
Length=563

 Score = 407 bits (1047),  Expect = 2e-132, Method: Compositional matrix adjust.
 Identities = 223/568 (39%), Positives = 340/568 (60%), Gaps = 19/568 (3%)

Query  13   QKATGAHFTPDKLAEVIAKRILDYFKGEKNR-VIRVLDPACGDGELLLAI-NKVAQSMNI  70
            +KATG+ +TP  LA  +A++I+        + V+R+LDPA GDG LL+ +  ++ +  + 
Sbjct  4    EKATGSTYTPASLARFVAEQIVAEAGSTLEKPVLRLLDPAVGDGALLIELLRQLKKVGSA  63

Query  71   QLELIGVDFDIDAINIA--NERLSRSGHKNFRLINKDFLEMV-SEGDNYDLFNIEELEPV  127
            +LE+ G D D +A+ IA  N R       +  LI  +FL++V +  +  D+F  +     
Sbjct  64   RLEVFGFDTDKNALAIAERNIRSELPDGASLELICANFLDLVLARAEQGDMFAEDCYGDF  123

Query  128  DIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNR  187
            D++IANPPYVRTQI+GA+ AQ++ ++F L GRVDLY AFL  M   L    I GVI SNR
Sbjct  124  DLLIANPPYVRTQIMGADIAQRIAKQFQLSGRVDLYYAFLAGMKCFLNRGAIAGVIVSNR  183

Query  188  YLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKF  247
            ++T K G S RK +  NF I  + DLGD+K F+ AVLPA+      + E Q  +S+   F
Sbjct  184  FMTIKSGTSVRKSIRENFCIRHVWDLGDTKLFDVAVLPAVLL---LSNEQQSCSSSDAAF  240

Query  248  FKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPENYKEPWI  306
              IYE  D EA   V++    L      +K+G+  V D + + +  G++ + E     W 
Sbjct  241  TSIYETKD-EAEILVDNPVEGL------SKNGVVEVSDSRRFRVQQGRLFTTEKSDGVWR  293

Query  307  LATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRP  366
            +ATE    W   V  + +    D   ++VG+KTTAD VFIR DW E  EE     + LRP
Sbjct  294  IATEASDCWLETVQAHTWRKFRDIGKIRVGVKTTADKVFIRKDWTE--EETEGAIEALRP  351

Query  367  IISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYV  426
            + +   AN++         ++LYTHE  DG+ +AI L++ P  K YL  H+E L  R YV
Sbjct  352  LTTHLIANRFRPMQEVPTTQILYTHETVDGRRRAIALDDKPHTKAYLLKHRETLERRTYV  411

Query  427  LKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSND  486
             KA RNWYEIWVP  P+ ++KPKI+F D S EP F+ +  GS+V+G+CYW++ +  +  +
Sbjct  412  RKAGRNWYEIWVPQKPADFEKPKIVFRDISQEPVFWLDRNGSIVNGDCYWLVSENGHEEE  471

Query  487  ILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRE  546
            IL+L++G+ NS F  +++D +F+N+LYAGRRR++TQYV ++P+PDP S  SK+I+ + + 
Sbjct  472  ILWLVLGVANSTFAEEFYDHSFRNQLYAGRRRFITQYVQEFPLPDPASDSSKQIVEMAKA  531

Query  547  LVNNKKETQDINEIENRIEKLILRAFDI  574
            +       +D +  E ++ +L+ +AF +
Sbjct  532  IYETTG-MEDTSAQEVQLSQLVYQAFGL  558


>WP_104316347.1 methyltransferase domain-containing protein [Rathayibacter rathayi]
 PPG88509.1 DNA methyltransferase [Rathayibacter rathayi]
 PPG98830.1 DNA methyltransferase [Rathayibacter rathayi]
Length=558

 Score = 407 bits (1046),  Expect = 2e-132, Method: Compositional matrix adjust.
 Identities = 211/575 (37%), Positives = 323/575 (56%), Gaps = 40/575 (7%)

Query  13   QKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQ--SMNI  70
            QK  G H+TP  LA+ +A+R+L          +RVLDPACGDGELLLA+ +VA+  ++++
Sbjct  10   QKRHGKHYTPAPLADFLAERLLAQISLAAG-ALRVLDPACGDGELLLALARVARRKNLDV  68

Query  71   QLELIGVDFDIDAINIANERLSRSG------HKNFRLINKDFLEMVSEGDNYDLFNIEEL  124
             LEL+G D D +AI  AN R +  G        NF L+  D L   S             
Sbjct  69   ALELVGFDLDAEAIQTANGRAAALGVPIAFECANF-LVASDSLIAAS-------------  114

Query  125  EPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVIT  184
               D +I+NPPYVRTQ LG + AQ L EK+ L GR+DL   F+      L+  G++ ++ 
Sbjct  115  --FDGVISNPPYVRTQQLGRDTAQLLAEKYGLSGRIDLTHPFVSIAPNLLRPGGVLALLC  172

Query  185  SNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFG-EKKNKEYQKENSN  243
            SNR+L+TK G + R+      + +E+ DLGD+K F AAVLPA+     ++N +     + 
Sbjct  173  SNRFLSTKAGSNMREIFSKTLSPVELYDLGDTKIFGAAVLPAVLIAIRQQNTQVHPRAT-  231

Query  244  VPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPENYKE  303
               F   YE SD    + V+     L E L    SG  + + + + +  G +    +   
Sbjct  232  ---FLSAYE-SDGPPDAPVD-----LFEALSRRTSGRATWDGRVFDVKAGTLTQGASGST  282

Query  304  PWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKL  363
            PW +   DE EW  +++   +      A ++VG+KTTADSVFIR  WG+LP EQ PE+ L
Sbjct  283  PWRMGGTDEAEWLARLDAGTWKTFGQIAKIRVGVKTTADSVFIRDSWGDLPLEQRPEEAL  342

Query  364  LRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASR  423
            L+P+ +     +W          VLY + +   +    ++E++PRA  YLESH+ERL  R
Sbjct  343  LQPLTTHHNIARWRFD--PGALSVLYPYRLDVERRTVPDMEQYPRAMAYLESHRERLEGR  400

Query  424  KYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKEN  483
            KYV  A R W+EIWV   P  W  PK++FPD S  P+F  +  G++V+G+CYWI      
Sbjct  401  KYVTDAGRQWFEIWVAQQPGRWKSPKLVFPDISELPRFALDRSGAIVNGDCYWIAVDDIG  460

Query  484  SNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISL  543
            S+D+  L++G+ NS    +++D    NKLYAGRRR+++QYV+ +PIP+P ++ S  ++  
Sbjct  461  SSDLALLMLGVANSSTAVRFYDHVCGNKLYAGRRRWISQYVSLFPIPEPSAVQSLAVVEF  520

Query  544  VRELVNNKKETQDINEIENRIEKLILRAFDIESLK  578
            VR LV  ++   +  E+   +++L++ AF+ ++ +
Sbjct  521  VRSLVEGERAVTE--EVAEELDQLVIAAFETKATR  553


>WP_093068541.1 type II restriction endonuclease subunit M [Thiothrix caldifontis]
 SEA67628.1 TaqI-like C-terminal specificity domain-containing protein [Thiothrix 
caldifontis]
Length=585

 Score = 405 bits (1042),  Expect = 2e-131, Method: Compositional matrix adjust.
 Identities = 219/559 (39%), Positives = 340/559 (61%), Gaps = 29/559 (5%)

Query  3    SVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRV-IRVLDPACGDGELLLA-  60
            S  +  +V+ +KA GA +TP  LA  +A +IL       ++  IR+LDPA G+G LL A 
Sbjct  9    SAPRYTSVTAEKAEGATYTPSTLAHFVATQILQAANLPSHQGKIRLLDPAVGNGILLEAM  68

Query  61   INKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHK----NFRLINKDFLEMVSE-GDN  115
            ++ + ++   ++E+   D    A++   +RL    HK       L  +DFL +V++ G  
Sbjct  69   LDTLPETTRQRVEVFAFDTHQPALHQTRQRLE---HKYPDIKLNLEKRDFLALVTDWGRQ  125

Query  116  YDLFNIE-ELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQL  174
             DLF+ +  L+P D+IIANPPYVRTQI+GA++AQ L  +F L GRVDLY  FL+ +++ L
Sbjct  126  QDLFSTKMPLQPFDLIIANPPYVRTQIIGADQAQLLANQFGLTGRVDLYYPFLLGISRVL  185

Query  175  KSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKN  234
               G  G+ITSNR++TTK G S R+ L+S F+I  + DLGD+K F+AAVLPA+       
Sbjct  186  APQGTAGIITSNRFMTTKSGQSVRQALLSCFDITHVWDLGDTKLFDAAVLPAVLV-VNTM  244

Query  235  KEYQKENSNVPKFFKIY---EQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSIS  291
            ++   +N ++P F  IY   E +   A  ++++  N    ++ +   G + ++  T    
Sbjct  245  QQSASDNKSIP-FSSIYATTEPASTYAEDALSALANPNNSIVSLPNGGCFHIKHGT----  299

Query  292  LGKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWG  351
            L    SPE     W +A++    W   V  + +G   D   ++VG+KTTAD VFIR DW 
Sbjct  300  LDNGDSPEGV---WRVASQSTDAWLDTVTSHTWGTFGDIGKIRVGVKTTADKVFIRHDWA  356

Query  352  ELPEEQIPEDKLLRPIISADQANKW-SVSLVGNN--KKVLYTHEIRDGQIKAINLEEFPR  408
            +LP   +PE  LL P+I+      + SV  V  N  K++LY HEIR G+ +A++++++P+
Sbjct  357  QLPSG-VPE--LLCPLITRHWGQPFKSVKPVKANHIKQILYPHEIRQGKRQAVDIKKYPK  413

Query  409  AKNYLESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGS  468
            A+ YLE++K  L++R YV++A R WYEIWVP DP+ W  PK++FPD + +P F+ +  G 
Sbjct  414  AQQYLEANKAVLSARTYVIEAGRQWYEIWVPQDPAAWSAPKLVFPDIAEKPTFWLDTDGG  473

Query  469  VVDGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYP  528
            +V G CYW+  K     D+L+L + + NS F+  ++D  F NKLYAGRRR++TQYV K+P
Sbjct  474  IVSGECYWLQCKNPADADLLWLALAVANSTFIESFYDHRFNNKLYAGRRRFITQYVEKFP  533

Query  529  IPDPESIYSKEIISLVREL  547
            +P+P+   SK +I L +++
Sbjct  534  LPNPDKAESKMLIQLAKDI  552


>WP_100876757.1 methyltransferase domain-containing protein [Janthinobacterium 
sp. 64]
Length=589

 Score = 405 bits (1041),  Expect = 3e-131, Method: Compositional matrix adjust.
 Identities = 222/577 (38%), Positives = 355/577 (62%), Gaps = 18/577 (3%)

Query  10   VSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA-INKVAQSM  68
            V +QK++GA +TP + A  +A +++   K  +N  IR+LDPACGDG LL A I ++ +++
Sbjct  20   VHQQKSSGATYTPLEFAAFVANQMVQVAKFPENGKIRILDPACGDGALLDALIARLPEAI  79

Query  69   NIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFL-EMVSEGDNYDLFNIEEL-E  125
              ++E++G D D  AI IA+ RL R     +  L  KDFL  +++     DL +  E+ E
Sbjct  80   KRRIEVVGYDTDPVAIEIASRRLRRDFPAVDVSLEQKDFLVHVLNLQGGGDLLSAAEVQE  139

Query  126  PVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITS  185
            P +++IANPPYVRTQI+GA++AQ+L + F L GRVDLY  FL+ ++Q L  +G+ GVITS
Sbjct  140  PFNLVIANPPYVRTQIIGAQQAQQLAQNFGLTGRVDLYYPFLLGISQVLAEDGVAGVITS  199

Query  186  NRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVP  245
            NR++TT+ G + R+ ++S F IL   DLGD+K F+AAVLP++    +  ++ Q  +++  
Sbjct  200  NRFMTTRSGQAVRRAMLSRFQILHAWDLGDTKLFDAAVLPSVLIA-RGTRDIQNPHTDGI  258

Query  246  KFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPENYKEP  304
             +  IYE  D+      NSE    +  L  +   + S+ D + + +  G + +  + +  
Sbjct  259  FYSSIYETKDV-----ANSEAKDALAALSADDDTVISIADGRRFRVRHGVLDNGGDPEGI  313

Query  305  WILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLL  364
            W +AT     W   V  N +        ++VG+K+TAD VF+RSDW +LP  + PE  LL
Sbjct  314  WRVATLSTDNWLGTVEGNTWDTFRRIGKIRVGVKSTADKVFVRSDWDDLPGGR-PE--LL  370

Query  365  RPIISADQANKWSVSL---VGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLA  421
            RP+I+   A ++  ++     + K++LY HE+      A++L  +P A  YLE+H+  L 
Sbjct  371  RPLITRKCARRFKAAIPAKAAHIKEILYPHEVAGSGRAAVDLSLYPGAARYLEAHRATLE  430

Query  422  SRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKK  481
            +R Y++ A R WYE+WVP DP+ W  PKI+FPD S +P F+ +  G +V+G CYW+    
Sbjct  431  ARTYLIDAGRKWYELWVPQDPAAWPLPKIVFPDISDKPIFWIDTDGGIVNGECYWLQCDN  490

Query  482  ENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEII  541
            EN  D+L+L + + NS F+  ++D  F NKLYAGRRR++TQYV  +P+PDPE   SKEI+
Sbjct  491  ENEQDLLWLAIAVGNSTFIETFYDHRFNNKLYAGRRRFITQYVELFPLPDPERDESKEIV  550

Query  542  SLVRELVNNKKETQDINEIENRIEKLILRAFDIESLK  578
            +L + L+++K  + + +++   ++ L+ R F ++  K
Sbjct  551  ALAK-LIHSKTPSVEADQLAVDLDGLVWRVFGLDREK  586


>PKB22639.1 TaqI restriction endonuclease [Janthinobacterium sp. 64]
Length=639

 Score = 405 bits (1042),  Expect = 1e-130, Method: Compositional matrix adjust.
 Identities = 222/577 (38%), Positives = 355/577 (62%), Gaps = 18/577 (3%)

Query  10   VSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA-INKVAQSM  68
            V +QK++GA +TP + A  +A +++   K  +N  IR+LDPACGDG LL A I ++ +++
Sbjct  70   VHQQKSSGATYTPLEFAAFVANQMVQVAKFPENGKIRILDPACGDGALLDALIARLPEAI  129

Query  69   NIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFL-EMVSEGDNYDLFNIEEL-E  125
              ++E++G D D  AI IA+ RL R     +  L  KDFL  +++     DL +  E+ E
Sbjct  130  KRRIEVVGYDTDPVAIEIASRRLRRDFPAVDVSLEQKDFLVHVLNLQGGGDLLSAAEVQE  189

Query  126  PVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITS  185
            P +++IANPPYVRTQI+GA++AQ+L + F L GRVDLY  FL+ ++Q L  +G+ GVITS
Sbjct  190  PFNLVIANPPYVRTQIIGAQQAQQLAQNFGLTGRVDLYYPFLLGISQVLAEDGVAGVITS  249

Query  186  NRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVP  245
            NR++TT+ G + R+ ++S F IL   DLGD+K F+AAVLP++    +  ++ Q  +++  
Sbjct  250  NRFMTTRSGQAVRRAMLSRFQILHAWDLGDTKLFDAAVLPSVLIA-RGTRDIQNPHTDGI  308

Query  246  KFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPENYKEP  304
             +  IYE  D+      NSE    +  L  +   + S+ D + + +  G + +  + +  
Sbjct  309  FYSSIYETKDV-----ANSEAKDALAALSADDDTVISIADGRRFRVRHGVLDNGGDPEGI  363

Query  305  WILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLL  364
            W +AT     W   V  N +        ++VG+K+TAD VF+RSDW +LP  + PE  LL
Sbjct  364  WRVATLSTDNWLGTVEGNTWDTFRRIGKIRVGVKSTADKVFVRSDWDDLPGGR-PE--LL  420

Query  365  RPIISADQANKWSVSL---VGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLA  421
            RP+I+   A ++  ++     + K++LY HE+      A++L  +P A  YLE+H+  L 
Sbjct  421  RPLITRKCARRFKAAIPAKAAHIKEILYPHEVAGSGRAAVDLSLYPGAARYLEAHRATLE  480

Query  422  SRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKK  481
            +R Y++ A R WYE+WVP DP+ W  PKI+FPD S +P F+ +  G +V+G CYW+    
Sbjct  481  ARTYLIDAGRKWYELWVPQDPAAWPLPKIVFPDISDKPIFWIDTDGGIVNGECYWLQCDN  540

Query  482  ENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEII  541
            EN  D+L+L + + NS F+  ++D  F NKLYAGRRR++TQYV  +P+PDPE   SKEI+
Sbjct  541  ENEQDLLWLAIAVGNSTFIETFYDHRFNNKLYAGRRRFITQYVELFPLPDPERDESKEIV  600

Query  542  SLVRELVNNKKETQDINEIENRIEKLILRAFDIESLK  578
            +L + L+++K  + + +++   ++ L+ R F ++  K
Sbjct  601  ALAK-LIHSKTPSVEADQLAVDLDGLVWRVFGLDREK  636


>WP_107673145.1 type II restriction endonuclease subunit M [Rhodobacter blasticus]
 PTE14455.1 type II restriction endonuclease subunit M [Rhodobacter blasticus 
DSM 2131]
Length=641

 Score = 405 bits (1041),  Expect = 2e-130, Method: Compositional matrix adjust.
 Identities = 220/575 (38%), Positives = 328/575 (57%), Gaps = 37/575 (6%)

Query  4    VQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINK  63
             ++   V + K+ GA +TP  LA+ +A RIL        R IRVLDPA G GELLLA+  
Sbjct  95   TKRYGDVGKAKSDGATYTPRALADFVAARILATADLASGRAIRVLDPAIGHGELLLAL--  152

Query  64   VAQSMNIQLELIGVDFDIDAINIANERLSRSGHK---NFRLINKDFLEMVSEGDNYDLFN  120
                ++  +E+ G + D  A+  A  RLSR   +   N RL    FL+ V +     LF 
Sbjct  153  -LDRIDGPVEVFGFETDHLALAEARRRLSREHPQAALNLRL--GSFLDHVLDDFTDGLFG  209

Query  121  IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGII  180
              E     IIIANPPYVRTQI+GA++AQ+L ++F L GRVDLY AFL+ M   L   G  
Sbjct  210  SPER--YHIIIANPPYVRTQIMGADRAQQLAQQFGLTGRVDLYHAFLLGMATVLAPEGAA  267

Query  181  GVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKE  240
            G I SNR++TTKGG S R  +++   + E+ DLGD+K F+AAVLPA+        E    
Sbjct  268  GFIVSNRFMTTKGGASARAEMMTGLRLREVYDLGDTKLFDAAVLPAVLIARGAGVE----  323

Query  241  NSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPE  299
             +  P F  IY+  D  A ++ +      IE L   K G  +V D +T+ +  G + +  
Sbjct  324  -AAAPSFLTIYQTKDEPAHTAADP-----IEAL--GKQGAVAVPDGRTFLVQHGTLDTGG  375

Query  300  NYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIP  359
            +    W LA+     W   V ++ +G   D   ++VGIKT AD VF+   W         
Sbjct  376  DPAGVWRLASAGVESWLATVERHTWGTFRDIGKIRVGIKTCADKVFLPKKWER-------  428

Query  360  EDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKER  419
            E +L RP+ +   A ++      +N+ VLY H   DG+ +A++L ++P +  YLE H+  
Sbjct  429  ELELHRPLTTHHNARRFRPE--PHNRLVLYPHHAVDGKKQAVDLSQYPASLTYLEQHRRT  486

Query  420  LASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIP  479
            L  R YV++A R WYEIWVP +P+ W  PK++F D S +P F+ + +G+VV+G+CYW+  
Sbjct  487  LEDRSYVIEAGRQWYEIWVPQNPADWPGPKLVFRDISEQPTFWMDLEGTVVNGDCYWLT-  545

Query  480  KKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKE  539
                  D+L+L +G+ NS F+ +++D+ F NKLYAGRRR++TQYV ++P+PDP S  ++E
Sbjct  546  ---GDEDLLWLAVGVANSTFIERFYDLRFNNKLYAGRRRFITQYVEQFPLPDPASSGARE  602

Query  540  IISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            I++  R+L     +  D   +E RI++++  AF +
Sbjct  603  IVTACRDLYARMADGPD-PALEQRIDRMVWAAFGL  636


>OAE13151.1 type II restriction endonuclease subunit M [Pseudomonas simiae]
Length=548

 Score = 401 bits (1031),  Expect = 3e-130, Method: Compositional matrix adjust.
 Identities = 215/541 (40%), Positives = 333/541 (62%), Gaps = 19/541 (4%)

Query  45   IRVLDPACGDGELLLAINKVAQSMNI-QLELIGVDFDIDAINIANERLSRSGHKNFRLIN  103
            IRVLDPA GDG LL A+ K   +  + ++ + G D D DA+  A+ RL R+      LI 
Sbjct  13   IRVLDPAAGDGALLEALLKRMPADTLSRVSVFGYDTDPDAVVRASSRLQRAFPGVSILIE  72

Query  104  -KDFLEMV-SEGDNYDLFNIEELE--PVDIIIANPPYVRTQILGAEKAQKLREKFNLKGR  159
             KDFL  V S   + DLF+    +  P D++IANPPYVRTQI+GAE+AQ+L + F L GR
Sbjct  73   EKDFLSHVLSLSGDADLFSDARTKQMPFDLVIANPPYVRTQIMGAEQAQQLAQSFGLTGR  132

Query  160  VDLYQAFLVAMTQQLKSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFF  219
            VDLY  FL+ +++ L   G+ G+ITSNR++TTK G + R+ L+S F I  + DLGD+K F
Sbjct  133  VDLYYPFLLGISRVLSEGGVTGIITSNRFMTTKSGQAVRRALLSKFIIKHVWDLGDTKLF  192

Query  220  EAAVLPAIFFGEKKNKEYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSG  279
            +AAVLPA+   +   KE       +  F  IYE  +  A ++++S F    E L ++ + 
Sbjct  193  DAAVLPAVLLAKGTKKELDPCVEGI-VFSTIYESKET-AVANLSSAF----EALAMSDNT  246

Query  280  LYSVED-KTYSISLGKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIK  338
            + SV D + + +  G + +  N +  W ++TE   +W   V++N +        ++VG+K
Sbjct  247  IVSVLDGRNFLVRHGLLDNGANAEGVWRISTESSDQWLATVDENTWNTFRRVGKIRVGVK  306

Query  339  TTADSVFIRSDWGELPEEQIPEDKLLRPIISADQANKWSVSLVGNNK---KVLYTHEIRD  395
            +TAD VF+R+DW +LP  + PE  LLRP+I+   A ++   +    K   +++Y HE   
Sbjct  307  STADKVFVRNDWSDLPGGR-PE--LLRPLITRHCARQFKACVPSKAKYIKEIMYPHESTS  363

Query  396  GQIKAINLEEFPRAKNYLESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDT  455
            G  KA++L  +P A  YLE H++ L +R Y++KA R WYE+WVP DP+ W  PKI+FPD 
Sbjct  364  GGRKAVDLSLYPVASRYLELHRDVLEARSYLIKAGRAWYELWVPQDPAAWSSPKIVFPDI  423

Query  456  SPEPKFFYEDKGSVVDGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAG  515
            S +P F+ + +G +V+G CYWI  ++E  ND+L+L + + NS F+  ++D  F NKLYAG
Sbjct  424  SEKPTFWMDTEGGIVNGECYWIQCEREEENDLLWLALAVANSTFIEFFYDHRFNNKLYAG  483

Query  516  RRRYLTQYVNKYPIPDPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIE  575
            RRR++TQYV ++P+PDP    ++ II+LV+E ++ +  +   N+  + +  L+ + F + 
Sbjct  484  RRRFITQYVEQFPLPDPARKETQAIINLVKE-IHEELPSSAANQKISELNALVWKVFGLN  542

Query  576  S  576
            +
Sbjct  543  A  543


>KVF76647.1 type II restriction endonuclease subunit M [Burkholderia vietnamiensis]
 KVF84302.1 type II restriction endonuclease subunit M [Burkholderia vietnamiensis]
 KVF90203.1 type II restriction endonuclease subunit M [Burkholderia vietnamiensis]
 KVF96246.1 type II restriction endonuclease subunit M [Burkholderia vietnamiensis]
Length=545

 Score = 401 bits (1030),  Expect = 3e-130, Method: Compositional matrix adjust.
 Identities = 208/540 (39%), Positives = 328/540 (61%), Gaps = 15/540 (3%)

Query  41   KNRVIRVLDPACGDGELLLA-INKVAQSMNIQLELIGVDFDIDAINIANERLSRS-GHKN  98
            K   IRVLDPA GDG LL A I  +  +   ++E+ G D D  AI IA  RL+      +
Sbjct  9    KRGTIRVLDPAVGDGALLDALIRCLPDATRKRVEVWGYDTDPAAIEIATARLADDFPGLS  68

Query  99   FRLINKDFLEMV-SEGDNYDLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLK  157
              +  KDFLE V +  ++ DLF   + EP  ++IANPPYVRTQILGAE+AQ L + F L 
Sbjct  69   VHIEQKDFLEHVLALQNDDDLFADGQQEPFHLVIANPPYVRTQILGAEQAQALAQSFGLT  128

Query  158  GRVDLYQAFLVAMTQQLKSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSK  217
            GRVDLY  FL+ +++ L   G+ GVITSNR++TTK G + R+ L+S F I+   DLGD+K
Sbjct  129  GRVDLYYPFLLGISRVLAEGGVTGVITSNRFMTTKSGQAVRRALLSQFQIVHAWDLGDTK  188

Query  218  FFEAAVLPAIFFGEKKNKEYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNK  277
             F+AAVLP++    K   + +  ++   +F  IYE  D     S     ++L  L  ++ 
Sbjct  189  LFDAAVLPSVLVA-KGTADTKHPHAAGIEFSTIYETKD----PSQAQAQDALAALDSIDD  243

Query  278  SGLYSVEDKTYSISLGKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGI  337
            + +   + + + +  G + +  + +  W +AT     W   V  N +        ++VG+
Sbjct  244  TVVEIADGRRFRVRHGTLDNGGDPEGLWRVATSATDTWLATVAANTWEAFRRIGKIRVGV  303

Query  338  KTTADSVFIRSDWGELPEEQIPEDKLLRPIISADQANKWSVSL---VGNNKKVLYTHEIR  394
            K+TAD VF+RSDW ++P  + PE  LLRP+++   A ++  ++     N K++LY HE+ 
Sbjct  304  KSTADKVFVRSDWADIPGGR-PE--LLRPLLTRHCARRFRAAVPSKAKNVKEILYPHEVV  360

Query  395  DGQIKAINLEEFPRAKNYLESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPD  454
            +G+  A++L  +P+A+ YLE H+E L +R YV++A RNW+E+WVP DPS+W  PK++FPD
Sbjct  361  NGRRSAVDLSRYPKAQRYLEEHREVLEARTYVIEAGRNWFELWVPQDPSMWPAPKLVFPD  420

Query  455  TSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYA  514
             S +P F+ + +G VV+G CYW+  + E   D+L+L + I NS F+  ++D  F NKLYA
Sbjct  421  ISDKPVFWIDTEGGVVNGECYWLCCEHEGEEDLLWLALAIANSTFIESFYDHKFNNKLYA  480

Query  515  GRRRYLTQYVNKYPIPDPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            GRRR++TQYV ++P+PDP    ++ II++ ++ V+    + + + +   +++L+   F +
Sbjct  481  GRRRFITQYVEQFPLPDPSRAETQTIIAMAKQ-VHTVTPSSEADALAAELDELVWSIFGL  539


>WP_082428003.1 type II restriction endonuclease subunit M [Pseudomonas endophytica]
Length=590

 Score = 402 bits (1032),  Expect = 9e-130, Method: Compositional matrix adjust.
 Identities = 221/573 (39%), Positives = 339/573 (59%), Gaps = 23/573 (4%)

Query  5    QKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKV  64
            ++ + V +QK+ GA +TP   A  +A +IL   +      IRVLDPA GDG LL A+ K 
Sbjct  15   RRYSEVGQQKSVGATYTPPDFAAFVADQILSVAQLPDRGEIRVLDPAAGDGALLEALLKR  74

Query  65   AQSMNI-QLELIGVDFDIDAINIANERLSRSGHKNFRLIN-KDFLEMV-SEGDNYDLFN-  120
                 + ++ + G D D  A+  A+ RL  +      LI  KDFL+ V S   + DLF+ 
Sbjct  75   MPVDTLSRVRVFGYDTDPSAVVRASARLQNAFPDVSILIEEKDFLDHVLSLSADSDLFSD  134

Query  121  -IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGI  179
                L P D++IANPPYVRTQI+G E+AQKL + F L GRVDLY  FL+ +++ L   G+
Sbjct  135  TRSTLMPFDLVIANPPYVRTQIMGTEQAQKLAQSFALTGRVDLYYPFLLGISRVLSEGGV  194

Query  180  IGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQK  239
             G+ITSNR++TTK G + R+ L+S F I+ + DLGD+K F+AAVLPA+    K  K+   
Sbjct  195  TGIITSNRFMTTKSGQAVRRALLSKFRIMHVWDLGDTKLFDAAVLPAVLLA-KGTKQIVD  253

Query  240  ENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISP  298
             +     F  IYE  +     +     ++++E L ++ + + S+ D + + +  G + + 
Sbjct  254  SDVEDIVFSTIYESKE-----NAVDHVSNVMEALTMSDNTVVSISDGRNFLVRHGLLDNG  308

Query  299  ENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQI  358
            E+    W ++T    +W   V+++ +        ++VG+K+TAD VF+RSDW  LP  + 
Sbjct  309  ESADGIWRISTASSDQWLATVHKHTWNTFRRVGKIRVGVKSTADKVFVRSDWSALPGGR-  367

Query  359  PEDKLLRPIISADQANKWSVSLVGNNK---KVLYTHEIRDGQIKAINLEEFPRAKNYLES  415
            PE  LLRP+I+   A ++   +    K   +++Y HE      KA++L  +P A  YLE 
Sbjct  368  PE--LLRPLITRYCARQFKACIPSKTKHIKEIMYPHESTSKGRKAVDLSLYPIAARYLEL  425

Query  416  HKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCY  475
            H+  L +R Y++KA R WYE+WVP DP+ W  PKI+FPD S +P F+ + +G +V+G CY
Sbjct  426  HRTTLEARSYLIKAGRAWYELWVPQDPAAWSSPKIVFPDISEKPTFWMDTEGGIVNGECY  485

Query  476  WIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESI  535
            W+  ++E  ND+L+L + + NS F+  ++D  F NKLYAGRRR++TQYV ++P+PDP   
Sbjct  486  WLQCEREGENDLLWLALAVANSTFIEFFYDHCFNNKLYAGRRRFITQYVEQFPLPDPARK  545

Query  536  YSKEIISLVR----ELVNNKKETQDINEIENRI  564
             S+ II L +    EL +N  + Q I+E+   I
Sbjct  546  ESQIIIDLAKAIHSELPSNAAD-QKISELNALI  577


>WP_084055495.1 type II restriction endonuclease subunit M [Carnimonas nigrificans]
Length=598

 Score = 401 bits (1030),  Expect = 2e-129, Method: Compositional matrix adjust.
 Identities = 232/585 (40%), Positives = 357/585 (61%), Gaps = 25/585 (4%)

Query  1    MMSVQKANTVSRQKATGAHFTPDKLAEVIAKRIL-DYFKGEKNRVIRVLDPACGDGELLL  59
            +M+  + + V  +K  GAH+TP  +A+ I++RIL D   GEK   +++ DPA GDGELL+
Sbjct  27   LMTPDRYSHVESRKKEGAHYTPTIIADFISQRILADVKLGEK---VQIADPAVGDGELLV  83

Query  60   AINKVA--QSMNIQLELIGVDFDIDAINIANERLSRSGHKN--FRLINKDFLEMVSEGDN  115
            ++      +SMN  +E+   D +  A+NI  ERL +  H +    + +KDFL++  E + 
Sbjct  84   SLISALKRRSMN-HIEVHAFDTNEKALNITRERL-KQLHSDVPIEIHHKDFLQVCLERET  141

Query  116  YDLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLK  175
            +       +   DIIIANPPY+RTQ+LGA++A+ L + F LKGR+D+YQAFLVAM   +K
Sbjct  142  FLGEMDASIPSFDIIIANPPYIRTQVLGADQAKLLSQNFGLKGRLDVYQAFLVAMKSVMK  201

Query  176  SNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNK  235
             NG+ GVI SNR++TTKG G  RK L   ++I  I D GD+K F+AAVLPA+      + 
Sbjct  202  PNGVAGVIVSNRFMTTKGAGEFRKTLYDEYSIKGIWDFGDTKVFDAAVLPAVMVMGVNS-  260

Query  236  EYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKI  295
                 N +VP F  IY     E +       ++ IE L    SGL +     Y +  G +
Sbjct  261  --SSRNDSVP-FSSIYFYEK-ELNKKNLPHVSNQIEALSF--SGLVTNPKSAYMVKHGHL  314

Query  296  ISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPE  355
                   + W L  E   +W  KV+   +   +D   ++VG+KTTAD+VFIR++W E   
Sbjct  315  TFDSKSSDIWRLQDEKSEKWLGKVDAKTWCRFKDIGKIRVGVKTTADNVFIRTNW-EKEV  373

Query  356  EQIPEDKLLRPIISADQANKWSVSLVGNNKK-VLYTHEIRDGQIKAINLEEFPRAKNYLE  414
              IPE  L+ P+++   A ++  +   N KK +LYTH + +G+    ++E+FP  K YLE
Sbjct  374  GYIPE--LVEPLVTHLVAARFKCN--DNEKKSILYTHHVVNGKRSVYDIEKFPITKKYLE  429

Query  415  SHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNC  474
            S KE+L+SRKY+ KA R WYEIWVP +P+LW   K+IF D + +P F+ +  GS+V+G+C
Sbjct  430  SKKEQLSSRKYIAKAKRLWYEIWVPQNPALWGTDKVIFRDITEQPTFWLDLDGSIVNGDC  489

Query  475  YWIIPKKEN-SNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPE  533
            YW+I + E    DIL+L++ + NS F+ +++D+ FQNKLY+ +RR++TQYV ++P+PDP 
Sbjct  490  YWMIRENEAMPEDILWLLLAVANSGFIEEFYDLKFQNKLYSNKRRFITQYVEQFPVPDPN  549

Query  534  SIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDIESLK  578
               SKEI+ L +E  +   +++ + ++E  I++LI   FD+  ++
Sbjct  550  REESKEIVKLTKERYHENDKSKHM-QLEQNIDQLIWSIFDVPHIE  593


>WP_107722796.1 type II restriction endonuclease subunit M [Celeribacter baekdonensis]
 AVW93549.1 type II restriction endonuclease subunit M [Celeribacter baekdonensis]
Length=518

 Score = 398 bits (1022),  Expect = 3e-129, Method: Compositional matrix adjust.
 Identities = 213/538 (40%), Positives = 313/538 (58%), Gaps = 37/538 (7%)

Query  41   KNRVIRVLDPACGDGELLLAINKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHK---  97
              R I+VLDPA G GELLLA+      ++  +E+ G + D  A+  A  RLSR   +   
Sbjct  9    SGRAIKVLDPAIGHGELLLAL---LDRIDGPVEVFGFETDHLALAEARGRLSREHPQAVL  65

Query  98   NFRLINKDFLEMVSEGDNYDLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLK  157
            N RL    FL+ V +     LF   E  P D+IIANPPYVRTQI+GA++AQKL ++F L 
Sbjct  66   NLRL--GSFLDHVLDDFTGGLFGTAE--PYDVIIANPPYVRTQIIGADRAQKLAQQFGLT  121

Query  158  GRVDLYQAFLVAMTQQLKSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSK  217
            GRVDLY AFL+ M   L   G  G I SNR++TTKGG S R  +++   + E+ DLGD+K
Sbjct  122  GRVDLYHAFLLGMATVLAPEGAAGFIVSNRFMTTKGGASARAGMMTGLRLREVYDLGDTK  181

Query  218  FFEAAVLPAIFFGEKKNKEYQKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNK  277
             F+AAVLPA+        E        P F  IY+  D  A ++ +      IE L   K
Sbjct  182  LFDAAVLPAVLIARGVGAE-----PATPSFLTIYQTKDQPAHTAADP-----IEAL--GK  229

Query  278  SGLYSVED-KTYSISLGKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVG  336
             G  S+ D +T+ +  G + +  +    W LA+     W   V+Q+A+G   D   ++VG
Sbjct  230  HGAVSIPDGRTFLVQHGTLDTGGDPAGVWRLASAGIESWLATVDQHAWGTFRDIGKIRVG  289

Query  337  IKTTADSVFIRSDWGELPEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDG  396
            IKT AD VF+   W    E       L RP+ +   A ++      +N+ VLY H   DG
Sbjct  290  IKTCADKVFLPKSWDCALE-------LHRPLTTHHTARRFRPE--PHNRLVLYPHHAVDG  340

Query  397  QIKAINLEEFPRAKNYLESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTS  456
            + +A++L ++P +  YLE H++ L  R YV++A R WYEIWVP +P+ W  PK++F D S
Sbjct  341  KKQAVDLSQYPASLAYLEQHRQTLEDRSYVIEAGRQWYEIWVPQNPTDWPGPKLVFRDIS  400

Query  457  PEPKFFYEDKGSVVDGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGR  516
             +P F+ + +G+VV+G+CYW+        D+L+L +G+ NS F+ +++D+ F NKLYAGR
Sbjct  401  EQPTFWLDLEGTVVNGDCYWLT----GDEDLLWLAVGVANSTFIERFYDLRFNNKLYAGR  456

Query  517  RRYLTQYVNKYPIPDPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            RR++TQYV ++P+PDPES  ++EI++  REL     +  D   +E RI++++  AF +
Sbjct  457  RRFITQYVEQFPLPDPESGGAREIVAACRELYTRLADGSD-PVLEQRIDRMVWAAFGL  513


>WP_133366234.1 type II restriction endonuclease subunit M [Qipengyuania sediminis]
Length=581

 Score = 400 bits (1027),  Expect = 3e-129, Method: Compositional matrix adjust.
 Identities = 215/584 (37%), Positives = 334/584 (57%), Gaps = 29/584 (5%)

Query  3    SVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAI-  61
            SV++   VS  KA G  +TP +L++ +A++I + F       I++LDP+ GDGEL  ++ 
Sbjct  9    SVKRYQDVSMTKANGETYTPAELSDFVARKICENFDFTDRDTIKILDPSVGDGELSCSLL  68

Query  62   NKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKN--FRLINKDFLEMVSEGDNY-DL  118
            N++    +  +EL   D +  A+ +A  R+    H +      NKDFL+   E D   DL
Sbjct  69   NEIRTHYSGNIELYAFDTNSLALAMAKSRIE-GIHPDCILHFENKDFLQFSIEEDREPDL  127

Query  119  FNIE---ELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLK  175
             +++   +    D+IIANPPYVRTQI+GA++AQ+L   F L GRVDLYQAFL+AM + L 
Sbjct  128  LSMQNNRDKPSFDLIIANPPYVRTQIMGADEAQRLAATFGLTGRVDLYQAFLLAMAKVLA  187

Query  176  SNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNK  235
              G  G I SNR+++ KGGGS R+ L     + E+ DLGD+K F AAVLPA+     K  
Sbjct  188  PKGAAGFIVSNRFMSIKGGGSLREKLRQMLALREVWDLGDTKLFNAAVLPAVIVANGKQC  247

Query  236  EYQKENSNVP-KFFKIYE---QSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSI  290
            E   EN +    F  IYE   QSD+ A+S +          L ++  G+ +V+D + + +
Sbjct  248  E---ENDDAAVAFTSIYETRDQSDLTAASPI----------LALSMEGVVAVDDGRRFLV  294

Query  291  SLGKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDW  350
              G + S       W +AT     W   V ++          ++VG+KT AD +FIR DW
Sbjct  295  KSGTLDSSGGADAVWRVATATGDAWMATVQRHTARTFGQIGKIRVGVKTCADKIFIRHDW  354

Query  351  GELPEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAK  410
                   +PE  LLRP+ +   A ++  +     + +LY H + DGQ +A +L++FP+++
Sbjct  355  EAATNGAMPE--LLRPLTTHHGAGRYRATTPKKVRHILYPHAVIDGQRRASDLDQFPKSR  412

Query  411  NYLESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVV  470
             YLE ++  L  R YV++  R WYEIWVP DP+ W  PK++F D S  P F+ +  GSVV
Sbjct  413  AYLEGNRAALEGRTYVIEGGRKWYEIWVPQDPASWSCPKLVFRDISERPTFWLDLDGSVV  472

Query  471  DGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIP  530
            +G+CYW+I   E   ++L+L + + NS F+  ++D  F NKLY+GRRR++TQYV ++P+P
Sbjct  473  NGDCYWMIAADERETELLWLAVAVANSTFIEAFYDHCFNNKLYSGRRRFITQYVEQFPLP  532

Query  531  DPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            DP +  ++ II+  +  +        +  +E  ++KL+ +AF +
Sbjct  533  DPATPLAQTIIAKAKA-IYEANHAPTVEGMERELDKLVWQAFGL  575


>WP_023173732.1 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 
[Gloeobacter kilaueensis]
 AGY58565.1 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 
[Gloeobacter kilaueensis JS1]
Length=559

 Score = 399 bits (1025),  Expect = 3e-129, Method: Compositional matrix adjust.
 Identities = 200/564 (35%), Positives = 324/564 (57%), Gaps = 26/564 (5%)

Query  13   QKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAINKVAQSMNIQL  72
             KA GA +TP  LA+ +A++I+ Y  GE+ R +R+LDPA GDG+LL+++     S    +
Sbjct  11   HKAQGATYTPAALADFVAEQIVRYLPGERKRPLRILDPALGDGQLLVSLLAKLGSEAAGV  70

Query  73   ELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFNIEELEPVDIIIA  132
             L G + D  A   A  RL+ +      +    FL++ SE             P DI+IA
Sbjct  71   TLHGYETDTAACERARARLAPA---VLTVEGTCFLDVASEKPT-------AAGPFDIVIA  120

Query  133  NPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGIIGVITSNRYLTTK  192
            NPPYVRTQILG+++++ L  +F L GR+DLYQAF++ +   L   G+ G+I SNR+++ +
Sbjct  121  NPPYVRTQILGSDQSRALARRFGLTGRLDLYQAFVLGIAGLLAPTGVAGLILSNRFMSIR  180

Query  193  GGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQKENSNVPKFFKIYE  252
             G S R+ L   F +  I DLGD++ F AAVLPA+   E  +      ++    F  IY 
Sbjct  181  AGASVRRALSERFQLRAIWDLGDTQLFAAAVLPAVVLLEGTDSPITTADT---PFSSIYR  237

Query  253  QSDIEASSSVNSEFNSLIELLEVNKSGLYSVED-KTYSISLGKIISPENYKEPWILATED  311
             S      + +        L  +N  G+  V D + + +  G + +P+     W + T +
Sbjct  238  TSAAATGCAAS-------PLAALNLDGVVEVTDGRRFEVRHGTL-APDPPGALWRMTTGN  289

Query  312  EYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPIISAD  371
               W  +V    +    +   ++VG+KT ADSVFIRSDW E P E+ PE  LL+P+ +  
Sbjct  290  SEHWLARVRSRTWKTFGELGKIRVGVKTCADSVFIRSDWQEWPPEERPE--LLKPLATHH  347

Query  372  QANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASRKYVLKANR  431
             A ++  +      +++Y H++  G+  A+ L+ +PR   YLE H++ L +R Y+L ANR
Sbjct  348  GAGRFRAN-SQTAWQIVYPHQVVAGRRVAVPLDAYPRTARYLEKHRQILIARSYLLAANR  406

Query  432  NWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWIIPKKENSNDILFLI  491
             WYE+WVP DP  W  PK++F D   EP F+ ++ GSVV+G+CYW+   K +  D L+L 
Sbjct  407  QWYELWVPQDPDGWAAPKLVFRDIVEEPTFWLDETGSVVNGDCYWLRCDKSSERDALWLA  466

Query  492  MGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYSKEIISLVRELVNNK  551
            + + NS F++ ++D  F NKLYAGRRR+++QYV K+P+P P+   S++++ L +++ +  
Sbjct  467  LAVGNSSFIAHFYDHCFHNKLYAGRRRFMSQYVEKFPLPRPDRPQSRQLVGLAQQIYSLP  526

Query  552  KETQDINEIENRIEKLILRAFDIE  575
              +  +  +E +++ L+ +AFD++
Sbjct  527  LGS-PVAALERQLDALVWQAFDLD  549


>WP_126298546.1 methyltransferase domain-containing protein [Corynebacterium 
matruchotii]
 VEI97726.1 Modification methylase VspI [Corynebacterium matruchotii]
Length=562

 Score = 399 bits (1024),  Expect = 5e-129, Method: Compositional matrix adjust.
 Identities = 214/575 (37%), Positives = 334/575 (58%), Gaps = 34/575 (6%)

Query  5    QKANTVSRQ-KATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAIN-  62
            QK N  +   K  G H+TP +LAE +A  ++     +++  + ++DPACGDGELL+A+  
Sbjct  3    QKTNRAAASVKVHGQHYTPPELAEFLANHVVAVADLDRSE-LTIIDPACGDGELLVAVVH  61

Query  63   --KVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN  120
              K A  + I L+LIG D D  A+  A  RL     +N ++I  DFL    E   +    
Sbjct  62   SLKSAGYLGI-LKLIGYDIDAAAVEQARARLHNIT-RNAQVIQGDFLLHQRELPTHS---  116

Query  121  IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGII  180
                  VDIII NPPYVRTQ LG E AQ L E+F+L GRVDL   F+ A ++ L ++G +
Sbjct  117  ------VDIIITNPPYVRTQNLGHETAQLLAEEFHLTGRVDLTHPFVAASSRLLMAHGTL  170

Query  181  GVITSNRYLTTKGGGSTRK-FLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQK  239
            G++ SNR+LTT  G + R+ F+  + +I E+ DLGD+K F+AAVLPAI    +     + 
Sbjct  171  GLLCSNRFLTTLAGENIRRTFMAGDLHITELYDLGDTKLFQAAVLPAIVIATRTTLRRE-  229

Query  240  ENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPE  299
                 P+F   Y      ++S+ N E   L + L    S + +   K Y + +G +  P+
Sbjct  230  ----TPRFVNAYHTP--TSTSTANLE---LFDALNAPTSSIAAHNGKLYDVRVGTLRMPD  280

Query  300  NYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIP  359
            + K PW L+     EW   +N   +    D A ++VGIKTTAD+VF+  DW    E + P
Sbjct  281  DTKTPWRLSDPTADEWLATINAATWRSFGDVAKIRVGIKTTADNVFLADDW----EHRAP  336

Query  360  --EDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHK  417
              E  LL P+I+      W++S      +VLY +++   + + +N++ +P AK+YL  H 
Sbjct  337  SVEADLLHPLITQHNITPWAIS-PHLTMRVLYPYDLTSEKRRVLNIDGWPGAKSYLLQHY  395

Query  418  ERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWI  477
            ++L+ R YV+K+ R WYEIWVP  P+LW  PKI+FPD S  P+F  +  G++V+GNCYWI
Sbjct  396  DQLSGRAYVVKSGREWYEIWVPQRPALWAAPKIVFPDISDTPRFALDTSGAIVNGNCYWI  455

Query  478  IPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYS  537
                  + DI +L++ + NS    +Y+D    N+LY+G+RR++TQY+N+ P+P P++  S
Sbjct  456  SLADIGNEDIAYLMLAVANSSLGVRYYDEVCGNRLYSGKRRWITQYINRLPLPYPDTDAS  515

Query  538  KEIISLVRELVNNKKETQDINEIENRIEKLILRAF  572
            +E+I++ ++L   +  T + ++   R+++L+ RAF
Sbjct  516  RELIAIAKQLAAGRNATGNRDDAVGRLDELVERAF  550


>WP_034672720.1 hypothetical protein [Acinetobacter sp. 272263]
 EXB83042.1 eco57I restriction-modification methylase family protein [Acinetobacter 
sp. 272263]
Length=559

 Score = 398 bits (1022),  Expect = 9e-129, Method: Compositional matrix adjust.
 Identities = 203/582 (35%), Positives = 357/582 (61%), Gaps = 35/582 (6%)

Query  2    MSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEK--NRVIRVLDPACGDGELLL  59
            +S+ +   +   K  G  +TP +LAE +AK+ + YF  +   N+ I +LDP+ GDG L+ 
Sbjct  3    ISLPRFQNIHEDKKNGVTYTPIELAEFVAKKTISYFDSQLFLNKKITILDPSIGDGILIK  62

Query  60   AINKVAQSMNI-QLELIGVDFDIDAI-NIANERLSRSGHKNFRLINKDFLEMVSEGDNYD  117
             +     +    ++E++GVD D      I +    +  +    L+  DFL         D
Sbjct  63   ELLLKLDTEKFSEIEIVGVDLDNSNFEQITSTVKEKYPNVTLTLLMDDFL---------D  113

Query  118  LFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSN  177
             +++ +    +IIIANPPY+RTQI+G+EK+QK+ + FNLKG+ D+Y  F++AM+  L ++
Sbjct  114  FYDVNKESRFNIIIANPPYIRTQIIGSEKSQKIAKDFNLKGKTDIYYGFMMAMSSLLSND  173

Query  178  GIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFE-AAVLPAIFFGEKKNKE  236
            G++  ITSNR+L+ K G   R +L+   +I  I DLGD+K F  AAVLPA+ F +K N +
Sbjct  174  GVLATITSNRFLSIKSGHVLRDYLLEALDIQSIYDLGDTKVFSSAAVLPALLFSKKNNNQ  233

Query  237  YQKENSNVPKFFKIYE----QSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISL  292
             + +    P+F  +YE    + D +   ++ SE +   + +++ KS         + I  
Sbjct  234  IKVD----PEFITVYEVKKSKQDHKEVETIFSEIDGTNQHIKIGKS--------KFEIIR  281

Query  293  GKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGE  352
            G +    +    W ++T++   W  KV  N +   +D   ++VG+K+TAD VFIR DW  
Sbjct  282  GILDLSNSKNNVWTVSTKESNSWLSKVTMNTWKTFKDIGPIRVGVKSTADKVFIRDDWDS  341

Query  353  LPEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNY  412
                  P+ +L++ +++++ A ++        K+++Y H   +G+ KA++++++P  K Y
Sbjct  342  FD----PKPELIKYLLTSECAQQFKAIRPNKPKEIIYPHTSENGKKKAVDIDQYPATKQY  397

Query  413  LESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDG  472
            LE++K++L+SR+Y++KA RNWYE+WVP +PSLW KPKI+FPD S +PKF+ + +G++V+G
Sbjct  398  LEAYKDQLSSREYLIKAGRNWYELWVPQNPSLWCKPKIVFPDISEKPKFWIDLEGNIVNG  457

Query  473  NCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDP  532
             CYWI P     N++L+L + + NSKF+ +++D  F NKLY+G+RR++ QYV ++PIPDP
Sbjct  458  ECYWITPDDSKDNELLWLCLAVANSKFIEQFYDYKFNNKLYSGKRRFMKQYVEEFPIPDP  517

Query  533  ESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            E   S+E+I L + ++ N  + ++ +++++++++L+ +AF +
Sbjct  518  ELQNSQELIKLSK-MIYNLLDQEESSKLKDKLDELVFKAFAV  558


>WP_128614130.1 type II restriction endonuclease subunit M [Pseudomonas sp. HMWF006]
 PTT03306.1 type II restriction endonuclease subunit M [Pseudomonas sp. HMWF006]
 PTT60913.1 type II restriction endonuclease subunit M [Pseudomonas sp. HMWF007]
 PTT83397.1 type II restriction endonuclease subunit M [Pseudomonas sp. HMWF005]
Length=590

 Score = 399 bits (1025),  Expect = 1e-128, Method: Compositional matrix adjust.
 Identities = 218/591 (37%), Positives = 349/591 (59%), Gaps = 31/591 (5%)

Query  2    MSVQKANT-----VSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGE  56
            +++  ANT     V +QK+ G  +TP   A  +A +++   +      IRVLDPA GDG 
Sbjct  7    LAILPANTRRYGDVDQQKSAGVVYTPADFAAFVADQMVSLAELPAQGEIRVLDPAVGDGA  66

Query  57   LLLAI-NKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLIN-KDFLEMV---S  111
            LL A+  ++   +  ++ ++G D D  A+  A+ RL +       LI  KDFL+ V   S
Sbjct  67   LLEALLMRMPTDILNRIRVVGYDTDPGAVARASVRLRKVFPDVSLLIEEKDFLDHVLSLS  126

Query  112  EGDNYDLFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMT  171
               N      +   P D++IANPPYVRTQI+G E+AQ+L ++F L GRVDLY  FL+ ++
Sbjct  127  GDANLSSSAAQAPMPFDLVIANPPYVRTQIMGGEQAQQLAQRFGLTGRVDLYYPFLLGIS  186

Query  172  QQLKSNGIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGE  231
            Q L   G+ GVITSNR++TTK G + R+ L+S F I  + D GD+K F+AAVLPA+    
Sbjct  187  QVLTEGGVAGVITSNRFMTTKSGQAVRRALLSQFKIDHVWDFGDTKLFDAAVLPAVLLA-  245

Query  232  KKNKEYQKENSNVPKFFKIYEQSD---IEASSSVNSEFNSLIELLEVNKSGLYSVED-KT  287
            +  K    ++     F  IYE  +   I+AS         + E L ++ + + S  D + 
Sbjct  246  RGIKAPSDQSVGEIAFSTIYECKENALIQASD--------VFEALAMSDNTIVSTPDGRN  297

Query  288  YSISLGKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIR  347
            +S+  G + + ++ +  W ++TE   +W   V++N +        ++VG+K+TAD VF+R
Sbjct  298  FSVRHGLLENGDHAEGVWRISTETGDQWLATVSENTWNTFRRIGKIRVGVKSTADKVFVR  357

Query  348  SDWGELPEEQIPEDKLLRPIISADQANKWSV---SLVGNNKKVLYTHE-IRDGQIKAINL  403
            SDW +LP  + PE  LLRP+I+   A ++     S   + K+++Y HE    G  KA++L
Sbjct  358  SDWSDLPGGR-PE--LLRPLITRHCARQFKARVPSQAKHMKEIMYPHEATSGGGRKAVDL  414

Query  404  EEFPRAKNYLESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFY  463
              +P A  YL+ H++ L +R YV+KA R WYE+WVP DP+ W  PKI+FPD S +P F+ 
Sbjct  415  SLYPLAARYLKGHRDVLEARSYVIKAGRAWYELWVPQDPAAWSSPKIVFPDISEKPTFWM  474

Query  464  EDKGSVVDGNCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQY  523
            + +G +V+G CYWI  ++E+ ND+L+L + + NS F+  ++D  F NKLYAGRRR++TQY
Sbjct  475  DTEGGIVNGECYWIQCEREDENDLLWLALAVANSTFIESFYDHRFNNKLYAGRRRFITQY  534

Query  524  VNKYPIPDPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            V ++P+PDP    ++ II+L +  ++ +  +   +++ + +  L+ + F +
Sbjct  535  VEQFPLPDPARKETQAIIALAKA-IHAELPSSAADQMISELNALVWQVFGL  584


>WP_005523499.1 methyltransferase domain-containing protein [Corynebacterium 
matruchotii]
 EEG25376.1 hypothetical protein CORMATOL_02990 [Corynebacterium matruchotii 
ATCC 33806]
 EFM47918.1 hypothetical protein HMPREF0299_5512 [Corynebacterium matruchotii 
ATCC 14266]
 SPW33142.1 Modification methylase VspI [Corynebacterium matruchotii]
Length=571

 Score = 398 bits (1023),  Expect = 1e-128, Method: Compositional matrix adjust.
 Identities = 216/575 (38%), Positives = 333/575 (58%), Gaps = 34/575 (6%)

Query  5    QKAN-TVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLAIN-  62
            QK N   +  K  G H+TP +LAE +A  I+     ++   + ++DPACGDGELL+A+  
Sbjct  3    QKTNRAAANVKVHGQHYTPPELAEFLADHIVAAADLDRPE-LTIIDPACGDGELLVAVAR  61

Query  63   --KVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLEMVSEGDNYDLFN  120
              K A  + I L+LIG D D  A+  A  RL R  +++ ++I  DFL        +    
Sbjct  62   SLKDAGYLGI-LKLIGYDIDAAAVEQARARL-RDVNRDAQVIQGDFLLHQRNLPTHS---  116

Query  121  IEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSNGII  180
                  VDIII NPPYVRTQ LG E AQ L E+F+L GRVDL   F+ A ++ L ++G +
Sbjct  117  ------VDIIITNPPYVRTQNLGHETAQLLAEEFHLTGRVDLTHPFVAASSRLLTAHGTL  170

Query  181  GVITSNRYLTTKGGGSTRK-FLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEYQK  239
            G++ SNR+LTT  G + R+ F+  + +I E+ DLGD+K F+AAVLPAI    +     + 
Sbjct  171  GLLCSNRFLTTLAGENIRRTFMAGDLHIAELYDLGDTKLFQAAVLPAIVIATRTALRREP  230

Query  240  ENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIISPE  299
                 P+F   Y      +SS+ N     L + L+   S + +   K Y + +G +  P+
Sbjct  231  -----PRFVSAYHTP--TSSSTTNL---GLFDALDTPTSNVAAHNGKLYDVRVGTLRMPD  280

Query  300  NYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIP  359
            + K PW L+     EW   +N   +    D A ++VGIKTTAD+VF+ +DW    E + P
Sbjct  281  DTKTPWRLSDPAADEWLATINTATWRSFGDVAKIRVGIKTTADNVFLANDW----EHRAP  336

Query  360  --EDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHK  417
              E  LL P+I+      W++S      +VLY +++   + + +N++ +P AK+YL  H 
Sbjct  337  LVEADLLHPLITQHNITPWAIS-PHLTMRVLYPYDLTSEKRRVLNIDNWPGAKSYLLQHY  395

Query  418  ERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNCYWI  477
            ++L+ R YV+K+ R WYEIWVP  P+LW  PKI+FPD S  P+F  +  G++V+GNCYWI
Sbjct  396  DQLSGRAYVVKSGREWYEIWVPQRPALWAAPKIVFPDISDTPRFALDTSGAIVNGNCYWI  455

Query  478  IPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPESIYS  537
                    DI +L++ + NS    +Y+D    N+LY+G+RR++TQY+N+ P+P P++  S
Sbjct  456  SLADIGDEDIAYLMLAVANSSLGVRYYDEVCGNRLYSGKRRWITQYINRLPLPCPDTDAS  515

Query  538  KEIISLVRELVNNKKETQDINEIENRIEKLILRAF  572
            +E+I+L + LV  +  T   ++   R+++L+ RAF
Sbjct  516  RELIALAKRLVTGRNATGSKDDAVGRLDELVERAF  550


>WP_077555043.1 type II restriction endonuclease subunit M [Rhodanobacter sp. 
B04]
 OOG64380.1 type II restriction endonuclease subunit M [Rhodanobacter sp. 
B04]
Length=589

 Score = 398 bits (1022),  Expect = 2e-128, Method: Compositional matrix adjust.
 Identities = 203/580 (35%), Positives = 332/580 (57%), Gaps = 22/580 (4%)

Query  5    QKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELLLA-INK  63
            Q+ + V +QK+ GA +TP   AE +A +++          IR+LDPA GDG LL A I +
Sbjct  15   QRYSHVDQQKSAGATYTPAAFAEFVADQMIRAASLPATGAIRILDPAVGDGALLDALIKR  74

Query  64   VAQSMNIQLELIGVDFDIDAINIANERLSRS-GHKNFRLINKDFLEMV-----SEGDNYD  117
            +  +   +  ++G D D +AI IA++RL +     + RL  +DFLE +      EG +  
Sbjct  75   LPLAARKRATVVGYDTDPEAIAIASQRLRQDFPALDLRLEQQDFLEHILQLQEREGTSP-  133

Query  118  LFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSN  177
                +  +P  ++IANPPYVRTQ++GA +A++L E F L GRVDLY  FL+ ++  L ++
Sbjct  134  --AADAAQPYHLVIANPPYVRTQVMGARQARQLAEGFGLSGRVDLYYPFLLGISNVLAAD  191

Query  178  GIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFEAAVLPAIFFGEKKNKEY  237
            G+ GVITSNR++TTK G + R+ L+S F I    DLGD+K F+AAVLP++          
Sbjct  192  GVAGVITSNRFMTTKSGQAVRRELLSRFRIAHAWDLGDTKLFDAAVLPSVLLAHGTTDPR  251

Query  238  QKENSNVPKFFKIYEQSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISLGKIIS  297
                  +  F  IYE  D   + + ++          V    +   + + + +  G + +
Sbjct  252  HPHTDGI-AFSSIYETRDPAQADAPDALAALAAADDTV----VAIADGRRFRVRHGDLDN  306

Query  298  PENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQ  357
             ++ +  W +AT    +W   V  + +        ++VG+K+TAD VFIRSDW  LP  +
Sbjct  307  GQHAEGLWRIATRVSDQWLATVAAHTWATFRRIGKIRVGVKSTADKVFIRSDWASLPGGR  366

Query  358  IPEDKLLRPIISADQANKWSVSLVGNNK---KVLYTHEIRDGQIKAINLEEFPRAKNYLE  414
             PE  LLRP+I+   A ++   +  + K   ++LY HE       A++L  +P+A  YL+
Sbjct  367  -PE--LLRPLITRHAARRFKADVPAHAKHIKEILYPHETTGSGRAAVDLRLYPKAARYLK  423

Query  415  SHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGNC  474
             H++ L +R YV++A R WYE+WVP DP+ W  PK++FPD S +P F+ +  G VV+G C
Sbjct  424  QHRDVLEARTYVIEAGRRWYELWVPQDPAAWSSPKVVFPDISEKPVFWIDTDGGVVNGEC  483

Query  475  YWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDPES  534
            YW+  +++   D+L+L + + NS F+  ++D  F NKLYAGRRR++TQYV ++P+PDP S
Sbjct  484  YWLQCERQGEEDLLWLALAVANSSFIEAFYDHRFNNKLYAGRRRFITQYVEQFPLPDPAS  543

Query  535  IYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
              ++ I++L +  ++ K  + +   +   +++ +   F +
Sbjct  544  EQARTIVALAKA-IHAKLPSAEAERLTADLDRRVWHVFGL  582


>WP_125825032.1 type II restriction endonuclease subunit M [Acinetobacter radioresistens]
 RSO65868.1 type II restriction endonuclease subunit M [Acinetobacter radioresistens]
Length=588

 Score = 398 bits (1022),  Expect = 2e-128, Method: Compositional matrix adjust.
 Identities = 203/582 (35%), Positives = 355/582 (61%), Gaps = 35/582 (6%)

Query  2    MSVQKANTVSRQKATGAHFTPDKLAEVIAKRILDYFKGEK--NRVIRVLDPACGDGELLL  59
            +S+ +   +   K  G  +TP +LAE +AK+ + YF  +   N+ I++LDP+ GDG L+ 
Sbjct  32   ISLPRFQNIHEDKKNGVTYTPIELAEFVAKKTISYFDSQLFLNKKIKILDPSIGDGILIK  91

Query  60   AINKVAQSMNI-QLELIGVDFDIDAI-NIANERLSRSGHKNFRLINKDFLEMVSEGDNYD  117
             +     +    ++E++G+D D      I +  + +  +    L+  DFL         D
Sbjct  92   ELLLKLDTEKFSEIEIVGIDLDSSNFEQINSTVIEKYPNVTLTLLMDDFL---------D  142

Query  118  LFNIEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAMTQQLKSN  177
             ++  +    DIIIANPPY+RTQI+G+EK+QK+ + FNLKG+ D+Y  F++AM+  L ++
Sbjct  143  FYDANKESRFDIIIANPPYIRTQIIGSEKSQKIAKDFNLKGKTDIYYGFMMAMSSLLSND  202

Query  178  GIIGVITSNRYLTTKGGGSTRKFLVSNFNILEIMDLGDSKFFE-AAVLPAIFFGEKKNKE  236
            G++  ITSNR+L+ K G   R +L+   +I  I DLGD+K F  AAVLPA+ F +K N +
Sbjct  203  GVLATITSNRFLSIKSGYVLRDYLLETLDIQSIYDLGDTKVFSSAAVLPALVFSKKHNNQ  262

Query  237  YQKENSNVPKFFKIYE----QSDIEASSSVNSEFNSLIELLEVNKSGLYSVEDKTYSISL  292
             + +    P+F  +YE    + D +   ++ SE     + +++ KS         + I  
Sbjct  263  IKVD----PEFITVYEVKKSKQDHKEVETIFSEIEGTNQHIKIGKSK--------FEIIR  310

Query  293  GKIISPENYKEPWILATEDEYEWFMKVNQNAYGFIEDFAHVKVGIKTTADSVFIRSDWGE  352
            G +    +    W ++T++   W  KV  N +   +D   ++VG+K+TAD VFIR DW  
Sbjct  311  GILDLSNSKNNVWTVSTKESNSWLSKVTMNTWKTFKDIGPIRVGVKSTADKVFIRDDWDS  370

Query  353  LPEEQIPEDKLLRPIISADQANKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNY  412
                  P+ +L++ +++++ A ++        K+++Y H   +G+ KA++++ +P  K Y
Sbjct  371  FE----PKPELIKYLLTSECAQQFKAIRPNKPKEIIYPHTSENGKKKAVDIDHYPATKQY  426

Query  413  LESHKERLASRKYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDG  472
            LE +K++L+SR+Y++KA RNWYE+WVP +PSLW KPKI+FPD S +PKF+ + +G++V+G
Sbjct  427  LEVYKDQLSSREYLIKAGRNWYELWVPQNPSLWCKPKIVFPDISEKPKFWIDLEGNIVNG  486

Query  473  NCYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQYVNKYPIPDP  532
             CYWI P     N++L+L + + NSKF+ +++D  F NKLY+G+RR++ QYV ++PIPDP
Sbjct  487  ECYWITPDDSKDNELLWLCLAVANSKFIEQFYDYKFNNKLYSGKRRFMKQYVEEFPIPDP  546

Query  533  ESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFDI  574
            E   S+E+I L + ++ N  + ++ +++++++++L+ +AF +
Sbjct  547  ELQNSQELIKLSK-MIYNLLDQEESSKLKDKLDELVFKAFAV  587


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Apr 3, 2019  2:24 AM
  Number of letters in database: 72,054,367,693
  Number of sequences in database:  198,058,131

Lambda      K        H
   0.317    0.136    0.391 
Gapped
Lambda      K        H
   0.267   0.0410    0.140 
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 198058131
Number of Hits to DB: 25537428
Number of extensions: 18735
Number of successful extensions: 5114
Number of sequences better than 100: 439
Number of HSP's better than 100 without gapping: 0
Number of HSP's gapped: 5072
Number of HSP's successfully gapped: 452
Length of query: 579
Length of database: 72054367693
Length adjustment: 163
Effective length of query: 416
Effective length of database: 39770892340
Effective search space: 16544691213440
Effective search space used: 16544691213440
T: 21
A: 40
X1: 16 (7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (20.4 bits)
S2: 85 (37.4 bits)
ka-blk-alpha gapped: 1.9
ka-blk-alpha ungapped: 0.7916
ka-blk-alpha_v gapped: 42.6028
ka-blk-alpha_v ungapped: 4.96466
ka-blk-sigma gapped: 43.6362


